Uses of Acutrine

Acutrine is a prescription drug, used in dermatology to treat patients with severe acne, causing inflammation and scarring. To ensure the effectiveness of using Acutrine, patients also need to follow the instructions of a specialist doctor, and refer to more information about the uses of Acutrine in the article below.

1.1. What is Acutrine? Acutrine belongs to the group of drugs used to treat dermatological diseases. Acutrine medicine includes the following ingredients:
Main active ingredient: Isotretinoin 10mg or 20mg. Excipients: Yellow Beeswax 9mg, Soybean Oil 126mg, Hydrogenated Coconut Oil 27mg, Lecithin 3mg, Concentrated Glycerin 22mg, Solution D - sorbitol 26mg, Ethyl vanillin, Blue No. 1, Red No. 1, Titanium dioxide, Water pure. The drug is prepared in the form of 10mg or 20mg softgels, blister packs of 10 tablets, box of 3 blisters.
Acutrine is recommended for use in adults.
1.2. What does Acutrine do? Acutrine is prescribed by doctors to treat severe acne that is resistant or minimally responsive to traditional treatments such as topical creams, lotions, oral antibiotics, or topical medications.
After a course of treatment, the drug works to completely reduce acne or improve long-term. But because of the dangerous adverse reactions, Acutrine should only be used to treat severely resistant acne.
Contraindications:
Patients who are allergic to the main ingredient Isotretinoin or any of the excipients of the drug. Women who are pregnant, are suspected of being pregnant or are breastfeeding. Women who are of childbearing age and want to become pregnant. Patients with excessively elevated blood lipids. The patient has renal dysfunction. Patients with vitamin A excess disorder Do not take concomitantly with tetracyclines. Children who have not yet reached puberty

2.1. How to take Acutrine Acutrine is taken orally, should be taken with meals during the day. Take Acutrine tablets whole with cooled boiled water, do not crush, crush or mix with any other mixture to drink. Follow your doctor's instructions exactly. 2.2. Dosage of Acutrine The dose of Acutrine depends on different subjects and according to the doctor's prescription:
Recommended starting dose: 0.5mg/kg body weight/day, treatment for 28 days. Maintenance dose: 0.1 to 1 mg/kg body weight/day depending on the subject. The maximum oral dose is 1 mg/kg body weight/day, but should only be used for short periods of time. The usual duration of treatment is 16 weeks. May continue with a second course of treatment in case nodular cystic acne is resolved. However, it is necessary to pause the drug for at least 8 weeks between treatments to assess the extent of skin improvement and the need for a further course of treatment. Handling missed dose:
In case you forget a dose of Acutrine, you need to take it as soon as you remember (usually it can be taken 1 to 2 hours before the time prescribed by the doctor). If it is almost time for the next dose, skip the missed dose.
Treatment of overdose:
Although the acute toxicity of the active ingredient isotretinoin is low, signs of hypervitaminosis A may still appear in the event of an accidental overdose.
Manifestations: severe headache, drowsiness, nausea or vomiting, discomfort and itching. Management: these symptoms will be able to gradually recover and decrease without any treatment intervention.

Acutrine may cause drowsiness or dizziness. These effects may be worse if you take them with alcohol or certain medications. Do not take more than the recommended dose or take Acutrine for longer than prescribed without checking with your doctor. Doing so will not improve the condition any faster, but may also increase the risk of side effects. A sudden decrease in night vision may occur while you are taking Acutrine. Use caution when driving at night Do not donate blood while taking Acutrine and for 1 month after stopping Acutrine. Worsening of acne may occur early in therapy. This does not indicate failure or the need to discontinue the drug. To avoid chapped lips, use a moisturizer or lip balm. Do not have cosmetic procedures to smooth your skin, including waxing, dermabrasion, or laser procedures, while you are taking Acutrine and for at least 6 months after you stop taking it. Acutrine may increase the chance of scarring from these procedures. Acutrine may make you more susceptible to sunburn. Avoid the sun, lights, or tanning beds until you know how you react to Acutrine. Use sunscreen or wear protective clothing if you must be outside for short periods of time. Acutrine may decrease bone strength in some patients. Patients who play high-impact sports may be at increased risk of bone problems (eg, fractures).

Common:
Anemia, decreased or increased platelets, increased erythrocyte sedimentation rate. Blepharitis, dry eye, conjunctivitis, eye irritation. Transaminase index increased. Cheilitis, dry skin, local exfoliation, dermatitis, itching, red rash, thinning of the skin (and risk of frictional injury). Arthralgia, back pain (especially in children and adolescent patients), myalgia. Blood triglycerides increase, high density lipoprotein decreases. Uncommon:
Decreased neutrophil count. Headache. Nosebleeds, nasopharyngitis, dry nose. Blood cholesterol increased, hematuria, proteinuria, blood glucose increased. Rare:
Anaphylactic reactions, allergic reactions, hypersensitivity. Depression, aggressive tendencies, mood swings, anxiety. Hair loss in patches. Infection with gram-positive bacteria (mucosal area). Swollen lymph nodes. Diabetes, increased blood uric acid index...

Concomitant use of Acutrine with vitamin A is not recommended due to the risk of developing hypervitaminosis A. Cases of benign intracranial hypertension have been reported with concomitant treatment with Isotretinoin and Tetracycline-containing preparations. Concomitant use of Acutrine with topical anti-acne agents or exfoliants should be avoided because the risk of local irritation may be increased.

The shelf life of Acutrine is 36 months from the date of manufacture. Store the medicine in a dry place, away from moisture, away from heat sources, away from direct light. Suitable temperature from 15 to 30 degrees C Keep out of reach of children. Use of Acutrine drug, effective in the treatment of acne, so in order for the drug to be effective when treating, patients need to carefully read the instructions before use and strictly follow the doctor's instructions.