Vinmec Research Institute of Stem Cell and Gene Technology

VCGT2018 | ANNOUNCEMENT

The 2nd Vinmec International Conference on Cell & Gene Therapy (VCGT) is an open international forum for presentation, discussion and exchange of the latest advances and challenges in research of Cell and Gene therapies. The main objective of the conference is to bring together researchers, academics, practitioners and students not only to share research results and practical applications but also to foster collaboration in research and education in Cell and Gene therapies. The conference will feature prominent invited speakers by top researchers from all over the world.

ANTIBIOTIC-INDUCED RELEASE OF SMALL EXTRACELLULAR VESICLES (EXOSOMES) WITH SURFACE-ASSOCIATED DNA

Recently, biological roles of extracellular vesicles (including exosomes, microvesicles and apoptotic bodies) have attracted substantial attention in various fields of biomedicine. Here the authors investigated the impact of sustained exposure of Jurkat cells to the fluoroquinolone antibiotic ciprofloxacin on the released extracellular vesicles.

EXOSOMES DERIVED FROM HUMAN INDUCED PLURIPOTENT STEM CELLS AMELIORATE THE AGING OF SKIN FIBROBLASTS

This study reported the effect of exosomes (EX) from the conditioned medium of human induced pluripotent stem cells (iPSCs) on aged human dermal fibroblasts (HDFs).

PRP IMPROVES STRUCTURAL IMPAIRMENT OF RAT TESTIS

Platelet-rich plasma (PRP) has a potential effect on tissue repair through proliferation and differentiation of tissue progenitor cells. The aim of this study was to evaluate the effect of PRP on the testis structure and function in infertile rat model by stereological method.

NATIONAL CORD BLOOD PROGRAM

The cord blood is collected into few minutes after a child’s birth from the delivered placenta by nurses working with the hospital's Obstetricians, Obstetric service nurses and other staff. This unit is no risk to mother or child.

NEW OBSERVATIONS MAY LEAD TO MORE EFFECTIVE CAR-T CELL THERAPIES

CAR-T cell therapy is the most effective for lymphoma treatment with up to 90% of patients responding to this therapy. However, the cost of CAR-T cell manufacture and side effects are still so high that most of patients can’t afford. In a recent nature paper, Fraietta et al (2018) has revealed a phenomena that may lead to reduction of CAR-T cell manufacture cost and side effect

ASSOCIATION BETWEEN MALE INFERTILITY AND LEVELS OF GH AND IGF-1

Growth hormone (GH) and insulin-like growth factor 1 (IGF-1) have been proposed to play a pivotal role in male infertility due to their anabolic effects. The aim of this study was to investigate possible associations between seminal plasma levels of GH and IGF-1 and sperm parameters.

Study on gene mutation in autism patients in Vietnam

Identification of genes in the autism spectrum is important for diagnosing, prognosing, genetic counseling and prenatal diagnosis for families with autistic children. Therefore, it is necessary to build up the data of autistic spectrum typical of Vietnamese people so that it can be used as a basis for developing diagnostic procedures for autistic children, prenatal screening for families in need.

THE DEPARTMENT OF BIOINFORMATICS AND MEDICAL STATISTICS

The Department of Bioinformatics and Medical Statistics strives to create novel informatics- and computationally-based methods, tools, algorithms and databases for basic biomedical, translational, and clinical research.