What is the cause of Down's disease?

Question
Hello doctor,
Can you tell me what is the cause of Down's disease? I have an aunt with Down syndrome in my family, so is there any impact when my granddaughter has a family? Was it transmitted from you? Thank you doctor.
Anonymous customer
Answer
Answered by Master, Doctor Bui Thi Phuong Hoa - Vinmec Stem Cell Research Institute and Gene Technology.
Hello,
With the question “What is the cause of Down's disease? ", the doctor would like to answer as follows:
Down syndrome has two main causes:
A new occurrence (Free Down syndrome) in people with Down syndrome. Down due to translocation, inherited in families. To find out if Down syndrome runs in the family, genetic testing of people with Down syndrome is needed. Or if you are worried about having a baby with Down syndrome, you can test your chromosomes and screen your baby for Down under the guidance of an obstetrician (ultrasound, double test, NIPT,...).
If you still have questions about the cause of Down's disease, you can go to a hospital under Vinmec Health System for further examination and advice. Thank you for trusting and sending questions to Vinmec. Wishing you lots of health.
Best regards!