Quantification of soluble antibody antigens

Autoimmune diseases account for about 3-5% of the population due to the formation of autoimmune antibodies against organ tissue components including cell nucleus, cytoplasm, cell membrane.... So consider Testing for circulating autoantibodies in autoimmune disease is essential, in which soluble antigen antibody testing is usually done after a positive ANA test to detect autoimmune disease. .

1. When is the quantitative test for soluble antibody antigens indicated?

Quantitative antibody soluble testing is usually ordered when a patient has evidence of a previous positive ANA test or has symptoms of an autoimmune disease such as:
Fever, persistent fatigue of unknown cause Muscle pain, joint swelling or pain Rash Raynaud's syndrome Urine protein Neurological disease such as epilepsy, depression Hemolytic 4 type anti-ENAs test for mixed connective tissue diseases, lupus erythematosus system and Sjogren's syndrome while testing for 6 types of anti-ENA helps in the diagnosis of scleroderma or dermatomyositis.
The two most common forms of soluble antibody antigens are Smith (SM) and ribonucleoprotein (RNP). If the test is negative but symptoms persist, the patient may have the test repeated. In addition, this test is also used to monitor patients who have been confirmed with autoimmune diseases to help observe the progression of the disease, see if the disease is severe or not.

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2. How is the soluble antibody antigen test performed?

In fact, the soluble antibody antigen test is a blood test so the patient does not need to do any special preparation before the test such as fasting or fasting. The usual blood collection procedure goes like this:
Wrap the bandage around your arm to prevent blood from circulating Disinfect the injection site with alcohol Inject into a vein to draw blood Remove the band around your arm after taking the required amount of blood Press the gauze After taking blood, the patient needs to gently press on the needle puncture area to stop bleeding, then normal activities

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3. The results of the soluble antibody antigen quantitative test

Negative results: normal patient, no circulating autoimmune antibodies
Abnormal results include:
Increased anti-SM antibody: systemic lupus erythematosus Increased anti-RNP antibody: disease mixed connective tissue, systemic lupus erythematosus or discoid lupus erythematosus Jo-I antibody elevation: pulmonary fibrosis

Kết quả của xét nghiệm định lượng kháng nguyên kháng thể hòa tan

Soluble antigen and soluble antibody tests help diagnose many dangerous diseases accurately. For more detailed information about this method, you can contact the hotline here for support.
MORE:
What are antigen and antibody tests for? What are antigens? What are antigens and antibodies?

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