Pathogenesis of endometriosis

Posted by Master, Doctor Vu Duy Thai - Obstetrician and Gynecologist - Women's Health Center - Vinmec Times City International Hospital

Endometriosis is the presence of endometrial-like tissue (glands and stroma) outside the uterus, causing a chronic inflammatory response, scar tissue and adhesions, which can be disfiguring anatomically woman's pelvis. What is the pathogenesis of endometriosis?

Many mechanisms have been proposed to explain the cause of endometriosis. However, there is no single mechanism that can explain all cases, but only some points of the disease. It is likely that the cause of endometriosis is due to many factors such as:
Reflux and implantation theory of the endometrium states that when menstruating, most of the discharge is vaginal, but there is also a A small portion flows backward into the fallopian tubes and into pelvic structures. Endometriosis at sites outside the pelvis is explained by dissemination of endometrial cells or tissues through lymph and blood vessels. Direct implantation theory is a possible explanation for endometriosis that develops during episiotomy, hysterectomy, and other surgical scars. The cellular immunological theory is the most recently proposed hypothesis, which holds that a deficiency of cellular immunity allows the endometrium to develop. Endometriosis is a common gynecological disease that can cause female infertility and cause discomfort and pain during the menstrual cycle. Therefore, the disease needs to be diagnosed and treated promptly.

To help customers detect and treat gynecological diseases early, including endometriosis, Vinmec International Hospital has a basic gynecological examination and screening package to help customers develop Early detection of inflammatory diseases makes treatment easy and inexpensive. Screening detects gynecological cancer (cervical cancer) early even when there are no symptoms.
Basic gynecological examination and screening package for female customers, has no age limit and may have the following symptoms:
Abnormal vaginal bleeding Having menstrual problems: irregular menstrual cycle, irregular menstrual cycle Irregular vaginal discharge (smell, different color) Vaginal pain and itching Female clients have several risk factors such as poor personal hygiene, Unsafe sex, abortion,... Female customers have other symptoms such as: Abnormal vaginal discharge, itching, pain in the private area, abnormal vaginal bleeding. In particular, when endometriosis is detected, customers will receive an in-depth examination to distinguish the disease form for the most effective treatment.