The role of uric acid quantification in urine

If blood uric acid test can help diagnose gout, monitor uric acid levels in cancer patients undergoing radiation or chemotherapy, uric acid urine tests can help. diagnose the cause of recurrent kidney stone disease and monitor the process of kidney stone formation.

Uric acid is a weak organic acid, an end product in the metabolism of purine nucleotides found in foods that humans consume on a daily basis. When entering the body, purine nucleotides will begin to react with the catalyst that is intestinal enzymes to release substances, when this reaction takes place continuously, it will create uric acid.
Everything will become normal if the body processes and excretes excess uric acid through urine and sweat. However, if the uric acid has problems in the processing process and cannot excrete all uric acid to the outside, it will increase the deposition of sodium urate salts in the joints and affect the movement of the child. In humans, the causative agent of typical gout or kidney stones, renal failure, renal tubular obstruction.

Although excess uric acid will cause many health problems, if the body is deficient in uric acid, it will also be extremely dangerous. Uric acid plays two particularly important roles in the body, that is:
Helps stimulate the brain to work effectively Uric acid plays a role in creating an energy source to help stimulate the brain to work more efficiently and maintain healthy brain function. maintain control of all life activities, scientific studies have shown that people with adequate uric acid levels, science will often have better thinking ability. If there is a lack of uric acid, people can face the risk of diseases such as Alzheimer's, Parkinson's...
As an antioxidant In the human body, uric acid is considered a strong reducing agent and a substance. It is a powerful antioxidant, so it is actively involved in plasma antioxidant reactions. A deficiency of uric acid will make it impossible to synthesize some other substances in the body.

Uric acid urine test is a routine test, has a very important role, is conducted when recurrent kidney stones are suspected or it is necessary to monitor the formation of kidney stones.
In addition, the quantitative test of uric acid in the urine also helps to accurately diagnose the condition in patients with:
Renal colic; Water retention in the kidneys; Renal failure when the source cannot be determined; Have arthritis; Joint pain. Urine uric acid test is useful in monitoring:
Patients with renal failure; Patients with blood diseases; Patients with anemia due to hemolysis; Patients who have received radiation therapy or chemotherapy; Patients addicted to alcohol; Monitor severity and prognosis of pregnant women with severe gestational toxicity at risk of eclampsia and preeclampsia.

Uric acid is the final metabolic product of a nitrogenous purine base. Quantitative testing of uric acid in the urine is carried out by enzyme kinetics method.
To perform this test, it is necessary to have a team of doctors, technicians trained in biochemistry, mechanical means, chemicals and reagents, consumables... ready to use.
Before conducting a quantitative urine uric acid test, the patient will be instructed by the technician to properly collect a urine sample, fill in all personal information on the test sheet and return it to the technician. for testing.
The urine sample will be put into the analyzer according to the machine's protocol, when the results are available, they will be analyzed and compared with the test sheet and returned to the patient.

Normally, the concentration of uric acid in the urine is 2.2 - 5.5 mmo/L/24 hours.
If uric acid levels are high in the urine, it means that the patient is related to gout, metastatic cancer, multiple myeloma, leukemia or a diet too rich in purines. For people who are at high risk for kidney stones and have high uric acid levels in the urine, medication may be necessary to prevent stone formation. Low urine uric acid levels often occur in people with kidney disease, chronic alcoholism, and lead poisoning.
In fact, for the body to develop normally, each person's blood always has a certain amount of uric acid. To prevent the risk that excess uric acid or uric acid deficiency will cause problems for the body, each person should pay more attention to daily diet, reasonable rest and regular health check-ups.