Is heterozygous alpha 3.7 hemolytic anemia during pregnancy dangerous?

Question
Hello doctor,
I am currently 20 weeks pregnant with twins. I have heterozygous alpha 3.7 hemolytic disease. Doctor let me ask if having hemolytic alpha 3.7 heterozygous during pregnancy is dangerous? Your husband is probably normal because his blood count is normal. Please advise, I would like to thank you doctor.
Nguyen Huong (1992)
Answer
Hello,
To the question “Is it dangerous to have hemolytic alpha 3.7 heterozygosity during pregnancy?” , the doctor would like to answer as follows:
Your husband needs to be consulted and ordered to be tested by a hematology geneticist to determine the risk of carrying the gene. If your husband has a low-risk alpha thalassemia gene mutation, your baby will also have a low risk of alpha thalassemia. The rate of mothers passing on mutations with alpha 3.7 deletion to their children is 50% and in the form of healthy carriers, there is no harm to health.
If you still have questions about heterozygous alpha 3.7 hemolysis during pregnancy, you can go to a hospital under Vinmec Health System for further examination and advice. Thank you for trusting and sending questions to Vinmec. Wishing you lots of health.
Best regards!

Answered by Doctor Bui Thi Phuong Hoa - Genetic consultant - Vinmec High-Tech Center.