Risk factors for prostate cancer


All men are at risk for prostate cancer. The most common risk factor is age. The older a man is, the greater his risk of prostate cancer. Some men are at increased risk of prostate cancer.

1. What is prostate cancer?


The prostate is a small gland located below the bladder in men and is part of the reproductive system. Some men get prostate cancer usually later, if the cancer grows on your prostate it will probably grow slowly. In rare cases, cancer cells can be more aggressive, grow quickly, and spread to other areas of your body. The earlier your doctor detects and treats a tumor, the better the chances of finding a treatment.

2. Cause


Like all cancers, the exact cause of prostate cancer is not easy to determine. In many cases, multiple factors may be involved, including genetics and exposure to environmental toxins, such as certain chemicals or radiation.
Ultimately, mutations in your DNA, or genetic material, lead to the development of cancer cells. These mutations cause the cells in your prostate to start growing uncontrollably and abnormally. Abnormal or cancerous cells continue to grow and divide until a tumor develops. If you have an invasive type of prostate cancer, the cells can metastasize or leave the original tumor site and spread to other parts of your body.
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3. Prostate Cancer Risk Factors


Age
The risk of prostate cancer increases with age, especially after age 50. More than 80% of prostate cancers are diagnosed in people 65 years of age and older. Older men diagnosed with prostate cancer may face unique challenges, particularly related to cancer treatment.
Family history
Prostate cancer runs in a family, known as familial prostate cancer, which accounts for about 20% of all prostate cancers. This type of prostate cancer develops due to a combination of shared genes and common environmental or lifestyle factors.
Hereditary prostate cancer, which means the cancer is inherited from a close relative, is rare and accounts for about 5% of all cases. Hereditary prostate cancer occurs when genetic changes, or mutations, are passed down in a family from one generation to the next. Hereditary prostate cancer may be suspected if family history includes any of the following:
3 or more first-degree relatives with prostate cancer Prostate cancer in 3 generations the same family 2 or more close relatives, such as a father, brother, son, grandfather, uncle, or nephew, on the same side of the family diagnosed with prostate cancer before age 55 If If a man has a first-degree relative with a father, brother or son with prostate cancer, his risk of prostate cancer is 2 to 3 times higher than the average risk. This risk increases even more with the number of relatives diagnosed with prostate cancer.
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Other genetic changes
Other genes that may increase the risk of developing prostate cancer include HPC1, HPC2, HPCX, CAPB, ATM, FANCA, HOXB13 and mismatch repair genes. However, none of them have been shown to directly cause prostate cancer or be specific for this disease. Research to identify genes associated with an increased risk of prostate cancer is ongoing, and researchers are constantly learning more about how specific genetic changes can affect cancer development. Prostate. Currently, there is no genetic test available to determine a man's chance of developing prostate cancer.
Exposure to Agent Orange
Prostate cancer is a disease associated with exposure to Agent Orange, a chemical used during the Vietnam War.
Diet
The exact role of diet in prostate cancer is unclear, but several factors have been studied.
Men who eat a lot of red meat or high-fat foods (especially dairy products) seem to have a slightly higher risk of prostate cancer. These men also tended to eat less fruits and vegetables. Doctors aren't sure which of these factors is responsible for the increased risk.
Some studies suggest that men who consume a lot of calcium (either through food or supplements) may have a higher risk of prostate cancer. Dairy foods (which are often high in calcium) may also increase the risk. But most studies have found no such association with the levels of calcium found in the average diet, and it's important to note that calcium is known to have other important health benefits. .
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References: healthline.com, cancer.ca, cancer.net, cancer.org

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