Uses of Mobocertinib

Mobocertinib is a kinase inhibitor that slows the growth of cancer cells. This is a prescription drug, available only at select drugstores. Patients need to take the medicine as prescribed by the doctor to limit the side effects caused by the drug.

Monocertinib is a kinase inhibitor - an enzyme that stimulates cell growth in the body. Kinases are of many types, they are involved in different stages of cell development. By blocking a specific enzyme from working, monocertinib can slow the growth of cancer cells. Monocertinib is active against exon 20 insertion mutations of the epidermal growth factor receptor (EGFR) found on some cancer cells. Your tumor will be tested for these mutations.
Dosage form: Monocertinib is made in capsule form.

Because it is produced in capsule form, Monocertinib is used orally. Patients can take the medicine with or without food, it is best to take it at the same time each day. When using the drug, the capsule should be swallowed whole, do not crush, chew or open the capsule.
In case the patient forgets to take Monocertinib for more than 6 hours, skip the dose and take the next dose the next day at the previously prescribed time.
In case the patient vomits after taking the drug, do not take an extra dose. Instead, take your next dose at the scheduled time.
During the use of therapeutic drugs, patients need to ensure that they use Monocertinib at the correct dose each time according to the prescription prescribed by the doctor. Before each dose of medicine, the patient should check that the medicine he is taking is exactly what the doctor has prescribed.
Monocertinib blood levels can be affected by certain foods and drugs. Therefore, these drugs and foods should be avoided during monocertinib treatment, including: grapefruit, grapefruit juice, itraconazole, ketoconazole, diltiazem, fluconazole, verapamil, rifampin, bosentan, and efavirenz.

Monocertinib causes many side effects directly related to the health and life of patients. However, there are a number of measures patients can take to control the effects of the drug.
Monocertinib causes heart problems:
Monocertinib can cause slow or irregular heartbeat or abnormal heart rhythm called QT prolongation. Before using this drug, the patient should have a heart function test. In addition, while taking the drug should be tested for electrolytes, including potassium and magnesium, because these substances can affect heart function. Patients should notify their doctor immediately if they feel an irregular heartbeat, dizziness or fainting. The drug also causes or worsens pre-existing heart problems such as congestive heart failure, restrictive cardiomyopathy, decreased heart function, and heart attack. Symptoms may include: sudden weight gain, swelling in the ankles or legs, pain and tightness in the chest, pain in the left arm, back or jaw, sweating, shortness of breath, rough skin, nausea, dizziness, lightheadedness,... Using Monocertinib can cause diarrhea:
Diarrhea is a serious side effect that occurs when using Monocertinib. Diarrhea can lead to dehydration, so it's important to control this side effect. The doctor should be contacted immediately when the patient begins to have diarrhea to determine which medication to take. To relieve diarrhea, the patient needs to contact the doctor for a prescription for treatment. Also, try eating low-fiber foods, white rice, and boiled or grilled chicken. Raw fruits, vegetables, wholegrain breads, cereals and nuts should be avoided. Skin and nail changes:
When using the drug, some patients may experience a rash, scaly skin or an itchy red rash. Patients should use an alcohol-free moisturizer on their skin and lips.
During monocertinib treatment, patients may develop skin inflammation around the skin of the nails, the cuticles of the toes or fingers, called paronychia. You may also have cuts or fissures that look like small paper cuts in the skin of your toes, fingers, or knuckles. These side effects may appear after several months of treatment or persist for many months after stopping treatment.
Monocertinib increases the risk of infection and reduces white blood cell count:
During treatment with Monocertinib, the number of white blood cells in the patient's body may decrease, increasing the risk of infection. higher. If you have a fever, sore throat or cold, burning when urinating, or untreated pain, you should tell your doctor right away as these are all warning signs of an infection. From there, the doctor will have a suitable treatment plan for each patient.
To prevent the risk of infection, sick people and sick family members need to wash their hands often, avoid crowded places, keep all cuts or scraps clean, don't handle pet waste, clean personal hygiene, regular oral hygiene,...
Drugs that cause side effects on the kidneys:
Using Monocertinib causes an increase in creatinine, affecting kidney function, making urine volume decrease, hematuria, ankle swelling or loss of appetite,... Patients need periodic kidney function tests during treatment.
Monocertinib causes mucositis, mouth sores:
Regular oral care is a measure that can help patients prevent or control mouth sores. Symptoms include: the inside of the cheeks or throat becomes white, sore or sore. In case of severe pain, the doctor may prescribe the patient to use pain reliever. In addition, to limit this side effect, the patient can apply some of the following measures:
The patient should use a soft-bristled toothbrush or cotton swab twice a day. Do not use mouthwashes that contain alcohol in the ingredients. Rinse your mouth with baking soda or warm water mixed with salt. If your mouth is dry, eat moist foods, drink plenty of water, and suck on sugar-free hard candies. Avoid smoking, drinking alcoholic beverages and citrus fruits. In addition, depending on the condition of each person, each patient will experience different side effects.

Exposure of the fetus to the drug can cause birth defects. Therefore, you should not become pregnant or become a father while using Monocertinib.
Patients need effective non-hormonal contraception, can use condoms, diaphragms, IUDs,... during treatment and at least 1 month after treatment for women women and 1 week after treatment for men. Even if your period stops or you believe you're not producing sperm, it's still possible to conceive and get pregnant.
Do not breast-feed during treatment and for at least 1 week after the last dose. Monocertinib is a capsule medicine used by mouth in the treatment of cancer. The drug slows down the growth of cancer cells. Drugs cause many unwanted effects, directly affecting the patient's body. Therefore, patients need to use the drug at the right time and in the right dose for the treatment process to be most effective.