Autologous Immune Enhancement Therapy (AIET)

1.Autologous Immune Enhancement Therapy (AIET) Scientific Name: Autologous Immune Enhancement Therapy (AIET) Technical Description Autologous Immune Booster Therapy is a therapy that strengthens the immune system. body fluids in preventing and killing cancer cells. Immune enhancement can be accomplished by obtaining natural killer cells (NKs) and cytotoxic T lymphocytes (CTLs) from the patient's body. They multiply and activate these cells in the laboratory and then transfer them back to the patient's body so that these immune cells will attack the cancer cells. Therapy helps cancer patients strengthen the immune system to stimulate active immune cells, increase the ability to recognize and attack cancer cells, increase the effectiveness of treatment when applying surgical methods, chemotherapy and radiation therapy...In Vietnam, autologous immunotherapy has been transferred to major hospitals. Vinmec International General Hospital is one of the first units to implement this special therapy. Previously, since 2015, Vinmec has cooperated with Japanese experts to welcome this technology.
2.What disease is this technique used to treat? Esophageal cancer Lung cancer Liver cancer Stomach cancer Pancreatic cancer

3.Indications and contraindications Indications:
All patients with the following cancers who are in the treatment stage or after the treatment ends can use immune-boosting therapy. Autologous fluid for treatment:
Lung cancer Stomach cancer Liver, bile, pancreatic cancer, Esophageal cancer Colon cancer Gynecological (cervical) cancer, breast cancer Brain cancer Solid tumors such as head and neck area, melanoma stage III, IV, metastatic recurrence during treatment or after the end of treatment In addition to indicated for patients undergoing cancer treatment, autologous immunotherapy also used for cancer patients undergoing palliative care can also use this therapy to strengthen the immune system, improve health and improve quality of life.
Contraindications:
People with autoimmune diseases. Are taking anti-rejection medication. T- or NK-cell leukemia. Being infected or suffering from serious medical diseases 4.Advantages and disadvantages of the technique Advantages:
Therapy helps patients to strengthen their general immunity, thereby helping to reduce chronic fatigue in cancer patients . Autologous immunosuppressive therapy helps patients who have finished cancer treatment reduce the risk of opportunistic infections: flu, pneumonia, pharyngitis, fungal infections. Increase the effectiveness of cancer treatment Cons:
High cost of implementation. The process of culturing immune cells must always strictly comply with the standards of the World Health Organization & the BIJ (Japan) technology transfer agency so that the preparations for infusion to the patient are safe at a high level. best.

5. Procedure Step 1: Take 50 - 150ml of blood for 01 culture. Step 2: Remove red blood cells, separate NK and T cells from blood volume Step 3: Culture and multiply in the laboratory in BINKIT medium for 2-3 weeks and then transported to hospitals , the center treats patients in 4oC-10oC conditions. In 2-3 weeks, it is possible to multiply the number of NK and T cells by 60-200 times. Step 4: Transfuse the immune cell block back to the patient. Time taken: 18 - 21 days 6.Things to keep in mind when performing this technique Therapy can be used independently. However, many studies show that the treatment effect is enhanced when combining treatment with other therapies such as chemotherapy, radiation therapy, heat therapy, surgery The number of times performed depends on the stage of the disease, the patient's condition, ..optimal is 6 times / 6 months and then maintain 1-2 times / year. Therapy can be continued until the cancer markers decline, or the tumor regresses or enters a non-progressive stage.