Bactronil topical side effects

1.1. Indications Bactronil is prepared in the form of an ointment for topical application. The main active ingredient is mupirocin 2% indicated in the treatment of primary and secondary skin infections caused by Staphylococcus aureus and other sensitive bacteria such as folliculitis, impetigo, boils...
1.2. Pharmacodynamics Active ingredient mupirocin is an antibiotic extracted from Pseudomonas Fluorescens, acting through the mechanism of inhibiting bacterial protein synthesis by reversibly binding to RNAt synthetase - the enzyme that catalyzes the formation of bacterial proteins. isoleucyl-RNAt. At low temperatures the drug has a bacteriostatic effect and the bactericidal effect is achieved at high concentrations. The antibacterial spectrum of Mupirocin is narrow, mainly affecting aerobic gram-positive bacteria such as Staphylococcus Aureus, S.epidermidis, S.saprophyticus... The drug is also effective on gram-negative bacteria such as Haemophilus influenzae, Escherichia coli. ..
1.3. Pharmacokinetics After topical application, very small amounts of mupirocin are absorbed into the general circulation. After absorption, a small amount of the drug is converted to monic acid, a metabolite that has no antibacterial activity and is eliminated mainly by the kidneys.

Bactronil topical has a dose depending on the age and condition of the patient. In particular, the recommended dose in children from 3 months of age and older and adults is to apply 2-3 times / day to the damaged skin. The maximum duration of use is 10 days depending on the patient's response.
Note that the drug should not be used in children under 3 months of age because there is no research evidence on safety and effectiveness when used in this subject.
Bactronil is used by topical application, the patient needs to clean the area to be applied before use, apply a small amount of ointment and rub gently to help the drug be better absorbed. The patient can use gauze to cover the wound area in case of need.

Bactronil topical may cause some side effects as follows:
During treatment with Bactronil may appear pain, needles, burning; Skin rash, itchy skin, easily sensitive skin and swelling.

4.1. Contraindications Contraindicated to use Bactronil topical in patients with hypersensitivity to mupirocin, patients who are allergic to any component of the drug or are sensitive to drugs containing Polyethylene glycol.
4.2. Precautions for use Pregnant women: There are currently no studies demonstrating the safety of Bactronil when treating pregnant women. Therefore, it is recommended to use Bactronil in pregnant women only when absolutely necessary and under the direction of a treating doctor.
Lactating women: There are no studies demonstrating the ability of Bactronil to be excreted in breast milk. Therefore, to ensure safety, patients need to stop breastfeeding during treatment with the drug.
Drivers and machine operators: Bactronil does not affect the patient's ability to drive and operate machines.
Special note: During treatment with Bactronil topical, patients should note:
Do not use the drug in patients with burns, especially large-scale burns; Use with caution in patients with renal failure; Do not apply the medicine to the nose, oral mucosa or eyes; Do not use the drug in the treatment of children under 3 months of age.

Bactronil can interact with other drugs as well as foods and drinks. Drug interactions increase the risk of side effects, increase drug toxicity, and decrease effectiveness. Therefore, to ensure the safety and effectiveness of treatment, patients need to inform the treating doctor of all medicines they are using, including over-the-counter drugs, prescription drugs, functional foods, vitamins. and minerals.
Bactronil medicine contains the active ingredient Mupirocin, indicated in the treatment of primary or secondary skin infections caused by sensitive bacteria such as folliculitis, impetigo, boils... To ensure effective treatment In order to avoid unwanted side effects, patients need to strictly follow the instructions of their doctors and pharmacists.
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