Drug Kurvelo: Uses, indications and precautions when using

Currently there are many different methods of contraception, including pills, condoms or spermicides. Among them, hormonal contraceptives are used very commonly, especially combined hormone pills. One of them is Kurvelo, a combination of a progestin and an estrogen.

Kurvelo is the trade name for a hormonal contraceptive that combines a progestin and an estrogen. So what does Kurvelo do? Kurvelo's main contraceptive mechanism is the suppression of ovulation during the menstrual cycle. Besides, to increase the effectiveness of birth control Kurvelo also has the following mechanisms:
Thickening the vaginal fluid to prevent sperm from meeting the egg (fertilization); Changing the lining of the uterus to prevent a fertilized egg from attaching, if the fertilized egg does not attach to the uterus, it will go out of the body. In addition to the contraceptive effect, Kurvelo can also regulate the menstrual cycle, reduce menstrual pain and reduce the amount of blood lost each cycle, reduce the risk of ovarian cysts and support the treatment of acne. Using Kurvelo does not protect the user or partner against sexually transmitted diseases (such as HIV, gonorrhea, chlamydia).

Patients should read the dosing information for Kurvelo that comes with or provided by a pharmacist for important information about when to take the medicine and what to do if a dose is missed. Kurvelo is to be taken by mouth as directed by your doctor, usually 1 time per day. Users should choose a time of day that is easy to remember and take it at the same time each day. Users need to maintain taking Kurvelo exactly as prescribed by their doctor. Different types of birth control pills will contain different levels of estrogen and progestin in each pill depending on when to take it, so users need to read the instructions on the package to find the right one and use the first pill in the pack. Take the remaining pills in the correct order, without skipping any pills.
Vomiting or diarrhea are factors that can reduce the effectiveness of Kurvelo oral contraceptives. If vomiting or diarrhea occurs, the user can use an additional backup method of birth control (such as condoms, spermicide). Taking Kurvelo after the evening meal or at bedtime may be helpful for people with stomach upset or nausea caused by the drug. Users can completely choose a different time to take the drug for easy remembering. However, regardless of the dosing schedule used, it is most important to take Kurvelo at the same time every day, 24 hours apart.
Kurvelo pill pack will include 21 active pills (with birth control hormone) and can add 7 inactive pills. The user should take one active pill once daily for 21 consecutive days. If the Kurvelo pack contains 28 pills, the user should take the inactive tablet once daily for 7 consecutive days after finishing the last hormone pill.
In contrast, for a pack of only 21 pills, the user does not take any pills for 7 days unless otherwise directed by the doctor. Users will get their period in the fourth week of the pill cycle. Once the last inactive pill in the pack has been taken or 7 days have passed without taking the pill, the user should start a new pack the next day with or without a period. If menstruation does not occur, the user should consult a doctor.
For the first cycle of using Kurvelo and not having to switch from another form of hormonal birth control (such as the patch, another birth control pill), the user should take the first active pill on Sunday. the first day after the start of your menstrual cycle or on the first day of your period. If your period starts on a Sunday, start taking Kurvelo on that same day. During the first cycle of use, users need to apply an additional form of hormone-free birth control (such as condoms, spermicide) for the first 7 days to give Kurvelo enough time to work.
Consult your doctor or pharmacist on how to switch from other forms of hormonal birth control (such as the patch, other birth control pills) to a Kurvelo product. If any information is not clear, users should consult the information on using Kurvelo or consult a doctor or pharmacist.

Possible side effects of Kurvelo include:
Nausea, vomiting; Headache; Full stomach; Chest tightness ; Swollen ankles/feet (water retention); Weight change. Vaginal bleeding between periods or missed or irregular periods may occur, especially during the first few months of using Kurvelo. If any of the above side effects of Kurvelo persist or get worse, tell your doctor or pharmacist immediately. If you miss your period for 2 consecutive periods (or 1 period if you have not used Kurvelo correctly), contact your doctor to take a pregnancy test.
Kurvelo may increase the user's blood pressure, so check your blood pressure regularly and let your doctor know if the results are high. Some other serious side effects of Kurvelo include:
Breast lumps; Mental/mood changes (such as new or worsening depression); severe stomach or abdominal pain; Vaginal bleeding that changes abnormally (such as continuous bleeding, sudden heavy bleeding, missed period); Dark urine, yellow eyes, yellow skin. Kurvelo can cause serious (sometimes fatal) problems with blood clots (such as deep vein thrombosis, heart attack, pulmonary embolism, stroke) so you need help getting help. get medical help right away if any of the following side effects occur:
Severe chest pain, pain spreading to the jaw or to the left arm; Confusion; Dizziness/sudden fainting; Pain, swelling, heat in the lower leg; Difficulty speaking; Sudden shortness of breath, rapid breathing; Unusual headache (including headache with vision changes or lack of coordination, migraine, sudden/very severe headache); Unusual sweating; Weakness on one side of the body; Vision changes (eg, double vision, partial/complete blindness). Very serious allergic reactions to the drug Kurvelo are very rare with any of the following symptoms:
Rash; Itching, swelling of the face/tongue/throat; Severe dizziness; Shortness of breath.

Before using Kurvelo, tell your doctor or pharmacist if you are allergic to any type of estrogen (such as ethinylestradiol, mestranol) or to any type of progestin (such as norethindrone, desogestrel) and any other medical conditions. any other allergy. Before using Kurvelo, the doctor or pharmacist should take the user's history, especially:
Blood clots (such as in the legs, eyes, lungs); Blood clotting disorders; Hypertension; Abnormal breast lump; Cancerous diseases (most notably endometrial cancer, breast cancer...); Increased cholesterol or blood triglycerides; Depression; Diabetes mellitus; Family or personal history of angioedema disorder; Gallbladder problems; headache or migraine; Heart problems such as heart valve disease, irregular heartbeat, previous heart attack; History of jaundice, jaundice during pregnancy, or jaundice with other hormonal contraceptives (such as the pill, patch); Kidney disease; Liver disease (including tumors); Stroke ; Thyroid diseases; Unexplained vaginal bleeding. If you have diabetes, Kurvelo may affect your blood sugar, so you should check your blood sugar regularly as directed by your doctor. Tell your doctor promptly if you have symptoms of hyperglycemia such as increased thirst or increased urination, the doctor will adjust the dose of diabetes medications, change the exercise program or improve the diet. of the patient.
Inform your doctor if you are taking Kurvelo moderately/will have surgery or have to sit in bed/chair for a long time (such as on a long flight), these conditions increase the risk of blood clots forming especially if the patient is using hormonal contraception. Users may need to stop taking Kurvelo for a while or take other special precautions.
Kurvelo can cause dark areas on the user's skin, so it's important to limit your time in direct sunlight and use sunscreen or wear protective clothing when outdoors.
It may take longer to get pregnant after stopping taking Kurvelo .
Kurvelo should not be used during pregnancy, if the user becomes pregnant or suspects pregnancy, tell the doctor immediately. If a user has just given birth or miscarried in the last 3 months, talk to their doctor about reliable forms of birth control and learn about when it's safe to start using birth control that contains estrogen. . Kurvelo reduces breast milk production and small amounts of it may pass into breast milk and cause unwanted effects on a nursing infant.

Drug interactions can change the way Kurvelo works or increase the risk of serious side effects. Some drugs that may interact with Kurvelo include:
Aromatase inhibitors (such as anastrozole, exemestane); Ospemifene; Tamoxifen; Tizanidine; Tranexamic acid; Combination drugs for the treatment of chronic hepatitis C. Some drugs can make hormonal birth control less effective by reducing the amount of birth control hormone in the user's body leading to pregnancy such as:
Griseofulvin; Modafinil; Rifamycins; seizure medicine (such as barbiturates, carbamazepine, felbamate, phenytoin, primidone, topiramate); HIV medicines (such as nelfinavir, nevirapine, ritonavir)... Patients should be aware of any new or sudden bleeding while taking Kurvelo as these could be signs of a new treatment. This birth control method is not working well. Kurvelo may interfere with certain laboratory tests (such as blood clotting factors, thyroid) possibly causing false test results. Symptoms of a Kurvelo overdose may include severe nausea and vomiting, and sudden and unusual vaginal bleeding.
Kurvelo users should have a comprehensive physical examination regularly, including tests such as blood pressure measurement, breast exam, pelvic exam, cervical smear... to monitor progress and check for symptoms. Kurvelo side effects. Follow your doctor's instructions to check your breasts and report any lumps right away when you feel it appear. Refer to the information on the Kurvelo pill packaging to better understand how to handle missed pills, users may need to use backup birth control methods (condoms, spermicides) to prevent pregnancy. If you often forget to take Kurvelo as directed, then you should contact your doctor to switch to another form of birth control.
Store the drug Kurvelo at room temperature, away from light and moisture, do not store the medicine in the bathroom, where the medicine should be kept away from children and pets. Do not flush Kurvelo down the toilet or pour it down the drain, dispose of it appropriately when it expires or when it is no longer needed.

Reference source: webmd.com