Limitations of the use of Domperidone

Domperidone is a drug used in the treatment of symptoms of vomiting and nausea, regulating intestinal motility, esophagus, stomach. Currently, on the market, Domperidone has many different dosage forms and strengths.

Domperidone is a drug used in the symptomatic treatment of vomiting and nausea. Currently on the market Domperidon drugs have many different dosage forms and strengths, specifically as follows:
Domperidon 10mg tablets Suppositories Domperidon 30mg Domperidon pills in the form of oral suspension 30mg/30ml Domperidon pills in effervescent form 10mg/pack Domperidon intravenous drug 10mg/2ml Domperidon stada 10mg In the drug Domperidon 10mg in addition to the main ingredient is Domperidone - a peripheral dopamine receptor antagonist, Domperidon 10mg drug also contains excipients such as: lactose monohydrate, povidon K30, Magnesium stearate, corn starch, .... help ensure the solubility, volume, stability of a tablet Domperidon 10mg.

With the main active ingredient is Domperidone - a peripheral dopamine receptor antagonist with antiemetic properties, so Domperidone is often used in the treatment of vomiting and antiemetic symptoms, regulating intestinal motility, oesophagitis, stomach.
Domperidone is indicated in the following specific cases:
Patients with symptoms of vomiting and nausea Gastrointestinal motility disorders Gastroesophageal reflux disease, esophagitis In addition, Domperidone also prescribed in some other cases when prescribed by a doctor.

Patients with a history of allergy or hypersensitivity to any ingredient of the drug Domperidone Patients with moderate to severe liver failure, patients with postoperative vomiting Patients with cardiovascular diseases such as: heart attack , myocardial infarction , arrhythmia Patient has a prolactinoma (prolactin)-releasing pituitary tumor. Patients with gastrointestinal bleeding, intestinal obstruction, gastric perforation, intestinal perforation. Patients with marked electrolyte disturbances (hypomagnesemia, hyperkalemia, hypokalemia) Concomitant use with drugs that prolong the QT interval - cardiac conduction time such as: hydroquinidine, sotalol, erythromycin, ... Patients under treatment with CYP3A4 inhibitors Children under 1 year of age

Domperidone 10mg drug is used as prescribed by the doctor. You can refer to the dosage of Domperidone as follows:
Domperidone dosage for adults, children over 12 years old and weighing 35 kg or more: Domperidone oral 10mg x 2-3 times/day, recommended dose The maximum recommended use is not more than 30mg/day (10mg/time x up to 3 times/day). To limit the side effects of Domperidone, only the lowest effective dose of Domperidone should be used for the shortest possible time. Domperidone should not be used for more than 1 week. Intravenous route: Use according to the doctor's prescription, if used for intravenous infusion, it must be administered very slowly.
Dosage of Domperidone for children from 12 years old and under: 0.25mg/kg body weight/time x up to 3 times/day, using the drug for no more than 1 week. However, some studies have shown that Domperidone increases the risk of sudden death and causes many harms in children under 12 years of age. Therefore, caution should be exercised when administering Domperidone to children 12 years of age and younger. Domperidone alternatives should be considered for the symptomatic treatment of vomiting and nausea in children 12 years of age and younger. Domperidone should only be used in children 12 years of age or younger when absolutely necessary. How to use Domperidone stada 10mg? The best time to use Domperidone stada 10mg is to take it before a meal because if taken after a meal Domperidone may be slow to absorb.
What to do if you forget to take a dose of Domperidone? If you forget to take a dose of Domperidone, take it as soon as you remember. However, if it is almost time for your next dose of Domperidone, skip the missed dose and take your next dose exactly as directed by your doctor. Never take a double dose of Domperidone to make up for a missed dose.

The drug domperidone can cause many unwanted effects for users. The following are the side effects of domperidone:
Increased risk of sudden death Anaphylaxis Headache, rash, itching, red eyes Menstrual disturbances, milky breasts, breast tenderness, breast swelling in men Dry mouth, thirst, diarrhea Irritability, drowsiness, fatigue, muscle weakness, cramps, nervousness, palpitations

Symptoms and signs of a Parocontin overdose include: lethargy, low blood pressure, dizziness, fainting, lightheadedness, heart rhythm disturbances, mouth swelling, swelling of hands and feet, loss of balance.
Measures to handle an overdose of domperidone is to consult a doctor or go to the nearest medical facility immediately and bring the remaining pills.

Domperidone can cause extrapyramidal reactions and somnolence may cause drowsiness, especially at the beginning of treatment. Therefore, after taking the drug, it is necessary to avoid tasks such as driving, operating machinery. and things that require alertness. In patients with Parkinson's disease: Domperidone should not be used for more than 12 weeks because of the increased risk of central nervous system adverse events. . While taking domperidone if the patient has any symptoms and signs of arrhythmia, it is necessary to talk to the doctor and stop the treatment if necessary. There is no clear evidence that the use of domperidone in pregnant women is harmful to the fetus or not, so the use of domperidone in pregnant women should be considered. Only use drugs when absolutely necessary and bring many benefits to the treatment.

Domperidone may interact with the following drugs including:
Anticholinergic drugs Acid secretion inhibitors or antacids Drugs that lower blood potassium, drugs that slow the heart rate Moderate CYP3A4 inhibitors such as: : diltiazem, some macrolide drugs, verapamil, ...

Store domperidone at room temperature, in a cool, dry place, away from light and reach of children.