Possible side effects of Azedra

Azedra medicine contains the active ingredient Iobenguane I 131 - a radioactive drug indicated in the treatment of adrenal myeloma, paraganglionic cell tumor. Let's learn about the uses and notes when using Azedra through the article below.

“What is Azedra medicine?”. Azedra contains the active ingredient Iobenguane I131 - a radioactive drug in the form of an injection. Azedra is indicated in the following pathologies:
Treatment of adrenal tumors; Treatment of rare neuroblastoma (paraganglioma) that has the potential to spread throughout the body.

Azedra belongs to the group of prescription drugs used by intravenous infusion. The dose of the drug prescribed by the treating doctor depends on the patient's medical condition and tolerability.
Azedra is usually given as the first infusion within 1 hour after the 3 radiographs are done. An additional dose is then taken at least 90 days apart from the previous dose.
Doctors may prescribe Azedra in combination with other drugs to help protect the patient's thyroid from exposure to Azedra radiation.
Patients should drink at least about 2 liters before the day of treatment with Azedra and for 1 week after taking the drug. Because Azedra is a radioactive drug, it can affect a patient's bladder if not eliminated properly in the urine.
During treatment with Azedra, patients may increase the number of times they urinate during the day, which is considered a mechanism to help the body get rid of waste products.
Medicines can reduce the number of blood cells. Therefore, the patient should have a blood count, blood pressure level and kidney function checked periodically.

Azedra can cause some side effects as follows:
Common: Decreased blood cell count, fatigue, vomiting, nausea, dizziness, low blood pressure; Serious side effects: Dry cough, chest tightness, trouble breathing, skin bruising, unusual bleeding, purple or red spots under the skin, symptoms of thyroid disease, joint pain, stiffness, pain or weakness muscle, low white blood cell count, mouth sores, skin sores, cough, sore throat, shortness of breath, low red blood cells, unusual tiredness, dizziness, shortness of breath, cold hands and feet. In case of experiencing side effects, the patient should stop using Azedra and notify the treating doctor for timely treatment.

Before treatment with Azedra, the patient needs to inform the doctor about the history of allergies to drugs, food - drinks, history of kidney disease.
Azedra may increase your risk of other cancers, such as leukemia. Patients should be informed of the risks before treatment.
Patients need to make sure that they are not pregnant before treatment for the following reasons:
Azedra increases the risk of harm to the fetus if the mother or father is being treated with the drug; Azedra is contraindicated in pregnant women. Note the use of contraception during drug treatment and at least 7 months after the last dose of the drug; For male patients who need to use effective contraception if their partner is able to become pregnant, continue using contraception for at least 7 months after the last dose of the drug; Patients should immediately inform the treating doctor in case of pregnancy while being treated with Azedra. For women who are breast-feeding: Do not breast-feed during treatment with Azedra and for at least 80 days after the last dose.

Some drugs that can affect the effects of Azedra are as follows:
Tramadol ; Medicines to treat high blood pressure ; antidepressants such as Bupropion, Amitriptyline, Duloxetine, Venlafaxine, Mirtazapine, Wellbutrin, Effexor, Cymbalta; Stimulant drugs such as Methylphenidate, Dextroamphetamine, Ritalin, Adderall. Above is information about Azedra medicine, patients need to carefully read the instructions for use, consult a doctor before using. When the drug is no longer in use, you need to collect and dispose of it according to the manufacturer's instructions.

Reference source: drugs.com