Possible side effects of Bicapain

Bicapain drug with the main ingredient is Meloxicam 7.5mg tablet form, belongs to the group of non-steroidal anti-inflammatory drugs. Meloxicam 7.5mg is used in the treatment of rheumatoid arthritis, ankylosing spondylitis, osteoarthritis and other inflammatory and painful conditions. However, in the process of taking the drug, there may be unwanted side effects, so to better understand the use of the drug, you can refer to the article below.

1. Effects - Indications of Bicapain

Bicapain is a non-steroidal anti-inflammatory drug (NSAID) belonging to the oxicam family, with anti-inflammatory, analgesic and antipyretic properties. Meloxicam has strong anti-inflammatory properties for all types of inflammation.
Meloxicam's potent anti-inflammatory mechanism inhibits the biosynthesis of prostaglandins, mediators of inflammation. In addition, when in vivo (in vivo), Meloxicam inhibits prostaglandin biosynthesis more strongly at the site of inflammation than in the gastric mucosa or in the kidney.
Absorption: Meloxicam after oral administration has an average bioavailability of 89%.
Distribution: Bicapain is strongly bound to plasma proteins, mainly albumin.
Metabolism: Bicapain is extensively metabolised, especially by oxidation at the methyl radical of the thiazolyl nucleus.
Elimination: Bicapain is eliminated in the urine and feces.
The mean half-life of Bicapain is 20 hours.

2. Bicapain drug effect

Bicapain has antipyretic, analgesic, anti-inflammatory and antiplatelet effects. However, the antipyretic effect is poor, so the drug is mainly used to relieve pain and anti-inflammatory.
Bicapain is used to treat the following cases:
Treatment of chronic inflammatory pain:
Osteoarthritis. Shoulder pain, back pain, knee pain due to inflammation. Rheumatoid arthritis. Ankylosing spondylitis

3. Dosage and how to use Bicapain

How to use Bicapain: Take orally.
Dosage:
Rheumatoid arthritis, ankylosing spondylitis: Take 02 tablets/time/day, drink after eating. Depending on the patient's response, the dose can be maintained at 1 tablet/time/day. Exacerbation of osteoarthritis: Take 2 tablets/time/day. Maintenance dose 1 tablet/time/day. Osteoarthritis: take 2 tablets/time/day. Maintenance dose 1 tablet/time/day. If the drug is used for a long time for the elderly, the dose should be 1 tablet/time/day. Bicapain should not exceed 15mg/time/day.

4. Side effects of Bicapain

During the course of taking Bicapain you may encounter the following side effects:
Digestion: indigestion, nausea, vomiting, constipation, flatulence, diarrhea, belching, esophagitis, stomach ulcer duodenum, latent or massive gastrointestinal bleeding, gastric perforation, proctitis. Hematology: anemia, blood count disorders (uncommon). Skin: itching, rash, stomatitis, photosensitivity, urticaria. Respiratory: acute asthma attacks may occur. Central nervous system: headache. dizziness, tinnitus. Cardiovascular: chest pain, hypertension, palpitations (uncommon).

5. Overdose or forgotten dose of Bicapain and treatment

Overdose: Bicapain is a drug prescribed by a doctor, patients do not arbitrarily take the drug without being examined. During use, if you accidentally overdose on Bicapain, you need to stop taking it, immediately notify your doctor or pharmacist when you have unusual symptoms. Family members need to bring medical records, all prescriptions/potions that have been used and are being used so that doctors can quickly diagnose and treat promptly.
Missed dose: Usually Bicapain can be taken 1-2 hours apart from the intended prescription. Unless there are strict regulations on the time of use, the medicine can be taken a few hours after forgetting. So if you have missed a dose, take it as soon as you remember. Do not make up for the missed dose as it can be dangerous for the body. You need to strictly follow the instructions or consult your doctor before deciding to take the drug.

6. Contraindications to the use of Bicapain

The following cases should not use Bicapain:
Patients with hypersensitivity to Bicapain's ingredients: Meloxicam or other non-steroidal anti-inflammatory drugs. Contraindicated in patients who have experienced symptoms of asthma, nasal polyps, angioedema or urticaria after taking aspirin or other non-steroidal anti-inflammatory drugs. The patient is suffering from progressive peptic ulcer, gastrointestinal bleeding, severe liver dysfunction. Bicapain is contraindicated in children under 15 years of age. Not for use by pregnant or lactating women. Normally, patients who are sensitive or allergic to any of the ingredients in Bicapain should not use the drug. Tell your doctor about all drug allergies you have.

7. Bicapain drug interactions with other drugs

Lithium, methotrexate. Birth control pills. Diuretic. Antihypertensive drugs, cyclosporin. Bicapain drug is a medicine to treat cases of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, pain caused by inflammation. However, to ensure the safe use of the drug, the correct indications and dosage of Bicapain should be used as prescribed by the doctor. If you have any questions about Bicapain drugs or side effects, please consult your doctor / pharmacist for advice.

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