Uses of Agiparofen

Agiparofen is often used to treat pain, anti-inflammatory and antipyretic for conditions such as back pain, menstrual pain or flu,... In order to achieve early therapeutic effect, patients need to take the drug. Agiparofen exactly as prescribed by your doctor.

Agiparofen belongs to the group of pain relievers, helping to improve mild to moderate pain for back pain, headache, toothache, menstrual pain or osteoarthritis pain. Agiparofen is a product of Agimexpharm Pharmaceutical Joint Stock Company, prepared in the form of 2-layer tablets, in which one layer is white and the other is orange.
Each box of Agiparofen includes 5 blisters x 10 tablets, containing 2 main active ingredients for anti-inflammatory and pain relief:
Paracetamol: 325mg content. Ibuprofen: 200mg.

Agiparofen is a combination of Paracetamol and Ibuprofen, helping to create an effective pain reliever and anti-inflammatory formula. Not only that, the use of Agiparofen at low therapeutic doses also reduces the risk of adverse events more than treatment with 2 separate active ingredients.
Usually, the drug Agiparofen will be prescribed by the doctor to reduce pain and inflammation for the following cases:
Arthritis, bursitis, back pain, rheumatism, muscle pain and sports injuries. Relieve fever, sore throat or flu. Reducing pain and inflammation in obstetrics, dentistry or orthopedics. Relieves toothache, headache, cancer pain and dysmenorrhea in women.

Although Agiparofen has very effective pain-relieving and anti-inflammatory properties, it is not suitable for all cases to use this drug. The following patients should avoid treatment with Agiparofen without a doctor's prescription:
Patients with a history of allergy or hypersensitivity to Ibuprofen, Paracetamol or any of the excipients in the drug Agiparofen . Patients with a history of hypersensitivity to NSAIDs, such as urticaria, bronchospasm, bronchial asthma, red rash,... Do not use Agiparofen for people with a history of related gastrointestinal bleeding. related to NSAIDs. Agiparofen is contraindicated in patients taking concomitant medications containing NSAIDs (including selective COX2 inhibitors) or drugs containing paracetamol. The patient has a progressive peptic ulcer. Patients with asthma, frequent bronchospasm or bleeding disorders. The patient is being treated with the anticoagulant Coumarin. People with congestive heart failure, liver failure, renal failure, renal dysfunction or volume reduction due to diuretics. Women who are pregnant in the first/last 3 months. Do not use Agiparofen in children under 12 years of age.

4.1. Recommended dosage of Agiparofen The following is the usual dose of Agiparofen for adults according to the general recommendation of a doctor:
Pain relief and anti-inflammatory treatment:
Dose for acute cases: Use from 1 to 2 tablet / time, use 3-4 times a day. Maintenance dose: Take 1 tablet / time x 3 times / day. The maximum recommended dose of Agiparofen is 12 tablets per day. Treatment of colds and fever:
Usual dose: Take 1-2 tablets / time x 3 times / day. The maximum recommended dose of Agiparofen is 6 tablets per day. Treatment of dysmenorrhea:
Usual dose: Take 1 tablet / time x 3-4 times / day. Patients need to take medication as soon as pain occurs. In case of necessity, the dose can be increased to 2 tablets / time, however, it is not allowed to exceed 6 tablets / day. The interval between doses of medication for menstrual cramps should be at least 4 hours. In the absence of a doctor's prescription, patients should avoid self-administering Agiparofen for pain relief for more than 10 days or for fever reduction for more than 3 days. 4.2. Instructions for effective use of the drug Agiparofen Agiparofen is made in the form of tablets, so patients need to take it orally. The most suitable time to take Agiparofen is after meals to avoid the effects of the drug on the stomach.
Before and during pain relief treatment with Agiparofen, patients need to strictly follow the dosage recommended by the doctor. Absolutely do not arbitrarily use, change the dose or stop the drug midway without the approval of the doctor.

When taking an overdose of Agiparofen, patients may encounter one of the following two cases:
Symptoms of Paracetamol overdose in Agiparofen: Liver damage, liver failure (if taken over 10g). About 24 hours after taking an overdose of Paracetamol, patients may experience initial symptoms such as nausea, vomiting, pallor, abdominal pain and loss of appetite. Within the next 12 - 48 hours, symptoms of liver damage will appear obvious. For patients with severe poisoning Paracetamol can progress to liver failure to encephalopathy - coma - death. Occasionally, patients may also experience other overdose symptoms such as tubular necrosis, acute renal failure, and arrhythmia. Symptoms of Ibuprofen overdose in Agiparofen: Nausea, abdominal pain, vomiting, lethargy, headache, somnolence, muscle spasms, central nervous system depression, hypotension, convulsions, tachypnea, tachycardia rapid or atrial fibrillation. Some cases may also experience other symptoms such as metabolic acidosis, acute renal failure, coma, apnea, hyperkalemia, respiratory failure or respiratory depression. If any symptoms of overdose appear after using Agiparofen, the patient should stop treatment and notify the doctor as soon as possible. Usually, symptomatic and supportive measures will be applied to patients who have taken an overdose of Agiparofen. To increase elimination as well as inactivate the drug, the doctor may suggest that the patient take measures such as inducing vomiting, gastric lavage, taking activated charcoal, salt bleach or diuretic.
Oral/intravenous N-Acetylcysteine ​​can be used as a specific antidote for Paracetamol overdose. Ideally, the patient should immediately take N-Acetylcysteine ​​within less than 36 hours of taking an overdose of Paracetamol.

When used at the right dose and for the recommended time, Agiparofen rarely causes unwanted side effects for patients. In certain cases, the treatment of pain, anti-inflammatory and antipyretic with Agiparofen can cause patients to experience some of the following side effects:
Common side effects: Abdominal pain, diarrhea, vomiting vomiting, nausea, abdominal discomfort, indigestion, rash, skin rash. Uncommon side effects: Urticaria, hypersensitivity, itching, headache, dizziness, gastrointestinal bleeding, peptic ulcer, gastrointestinal tract, mouth ulcer, vomiting blood, Crohn's disease gastritis , exacerbation of colitis, flatulence, pancreatitis, constipation, prolonged bleeding time. Very rare side effects: lethargy, fatigue, anemia, pancytopenia, neutropenia, leukopenia, swelling of face/throat/tongue, hypotension, tachycardia, angioedema, severe shock, anaphylaxis, hallucinations, depression, confusion, aseptic meningitis, somnolence, optic neuritis, tinnitus, dizziness, hearing loss, edema, heart failure, hypertension , asthma, dyspnea, exacerbation of asthma, bronchospasm, hepatitis, abnormal liver function, jaundice, Stevens-Johnson syndrome, toxic epidermal necrolysis, erythema multiforme, purpura blood, exfoliative skin, photosensitivity, nephrotic syndrome, acute/chronic renal failure, interstitial nephritis. If you notice any unusual symptoms during treatment with Agiparofen, you should stop taking the drug and immediately go to a medical center for specific treatment.

According to experts' recommendations, patients should avoid using Agiparofen at the same time as the following other drugs:
Drugs containing Paracetamol, Ibuprofen or drugs of the non-Steroid anti-inflammatory group. Anticonvulsants. Alcohol. Coumarin/Indandion derivatives anticoagulant. Metoclopramide or Domperidone. Isoniazid drug. Cholestyramine. Chloramphenicol drug. Quinolone antibiotic. Methotrexate drug. Digoxin drug. Diuretics / Furosemide. Above is information about uses, dosage and precautions when using Agiparofen. To ensure safety for your health and maximize the effectiveness of your treatment, you need to take Agiparofen exactly as directed by your doctor.