Uses of Agirisdon

Agirisdon has the main ingredient is Risperidone 2mg, belongs to the group of antipsychotics. The drug is prepared in the form of film-coated tablets, box of 2 blisters, 10 blisters x 10 tablets. Understanding the effects as well as strictly complying with the indications and doses of Agirisdon will help patients improve treatment effectiveness and prevent unwanted side effects.

The active ingredient Risperidone in Agirisdon is a second-generation antipsychotic drug that has antipsychotic effects by selectively antagonizing serotonin type 2 (5-HT2) and dopamine type 2 receptors. (D2). Risperidone has both 5-HT2 affinity like Clozapine and dopamine D2 affinity like Haloperidol.
According to traditional hypotheses, the antipsychotic effect is through inhibition of dopamine D2 receptors. The effect of Risperidone may be due to an action on the D2 receptor or another site and a number of other effects to produce atypical properties of the drug. While the ability to inhibit dopamine D2 causes psychotic depression, the effect on serotonin enhances the effect of negative symptoms of schizophrenia and reduces extrapyramidal symptoms. Risperidone has antipsychotic activity even at low doses and is more effective than Haloperidol in preventing disease recurrence. In particular, Risperidone is useful in patients with severe extrapyramidal reactions when taking antipsychotics because Risperidone is less likely to cause this reaction.

Agirisdon is indicated in the following cases:
Mental disorders; Acute and chronic schizophrenia; Moderate to severe acute mania. The drug Agirisdon is not used in the following cases:
The patient has a history of hypersensitivity to Risperidone or any of its ingredients; People who overdose on barbiturates, alcohol or opiate preparations.

Usage: The drug Agirisdon is used orally. Patients should swallow Agirisdon 2mg tablets whole, do not chew, break, or crush as this can reduce the effectiveness of the drug. The drug can be taken with or without food.
Dosage:
Acute and chronic schizophrenia:
Adults:
First dose on the first day: 2 mg/day, orally once or divided into 2 times/day. Second day: 4 mg/day, orally once or divided into 2 times/day. The third day: 6 mg/day, orally once or divided into 2 times/day. Fourth day onwards: Maintain the same dose, adjust the dose if necessary. Maximum dose: 4 - 8 mg/day, orally once or divided into 2 times/day. Children or first time users:
First dose should be lower: 1 mg/day. Adjust the dose more slowly, depending on the clinical response of the patient, the first target dose should be 2 mg/day. The optimal dose in this subject is 1-3mg/day. Note:
Some patients may experience extrapyramidal symptoms when the dose is increased above 2 mg/day. When extrapyramidal symptoms are present, the dose must be reduced. Usually, doses above 6mg/day not only do not increase the effectiveness but also cause many side effects. The optimal duration of treatment with risperidone for patients with schizophrenia is currently unknown. However, according to studies, the drug can be effective for up to 2 years Bipolar disorder:
Adults: Manic episodes or mixed episodes of bipolar disease:
First dose: 2 - 3 mg/day, orally 1 times. May increase or decrease by 1 mg/day after at least 24 hours. Risperidone has a short-term (less than 3 weeks) antimanic effect at doses ranging from 1 to 6 mg/day, with doses above 6 mg whose safety has not been determined. If treatment is longer than 3 weeks, the benefits and risks should be reassessed. Elderly, liver failure, renal failure, orthostatic hypotension:
Start with 0.5mg/day. The dose can be increased as needed, but the patient should be able to tolerate the dose in increments of no more than 0.5 mg at a time. Doses above 3 mg/day should not be maintained.

Symptoms of overdose: Drowsiness, tachycardia, sedation, hypotension, convulsions, prolonged QT interval and respiratory arrest. Treatment:
When using Agirisdon overdose, the patient should stop the drug immediately and go to the medical facility for timely treatment. First, the patient must be ventilated and maintain an adequate oxygen supply. Risperidone does not have a specific antidote, gastric lavage and activated charcoal should be done as soon as the patient takes an overdose. Clinical signs and ECG should be monitored to detect arrhythmias and antiarrhythmic drugs should be administered if necessary. In addition, symptoms of overdose such as hypotension, circulatory failure, and extrapyramidal symptoms should be treated and supportive therapy should be given.

When using Agirisdon, patients may experience some unwanted side effects such as:
Common: Dizziness, anxiety, somnolence, insomnia, extrapyramidal symptoms, Parkinson's syndrome, constipation, sadness vomiting, indigestion, abdominal pain, sinusitis, sore throat, shortness of breath, dry skin, joint pain, tachycardia, hypotension, blurred vision, back pain and fatigue Rare: Decreased concentration, memory loss, hypersexuality, hypertonia, stupor, paresthesia, flatulence, diarrhea, stomatitis, bronchospasm, pneumonia, increased or decreased sweating, acne, hypertension, atrioventricular block , eye accommodation disorders, hematuria, breast tenderness, epistaxis and purpura. If the patient experiences the above symptoms while using Agirisdon, it is necessary to stop taking the drug and consult a doctor or go to a medical facility for appropriate treatment.

Agirisdone may interact if used concurrently with the following drugs and substances:
Quinidine: Increases the atrioventricular block effect of Risperidone; Antihypertensives: Concomitant administration of risperidone increases the antihypertensive effect and increases the risk or worsening of orthostatic hypotension; Levodopa or dopamine agonists: Antagonistic effects; Carbamazepine, Clozapine : Increased effect of Risperidone; Drugs acting on the central nervous system, alcohol: Increases the effect of risperidone.

Be careful in people who drive and operate machinery because it causes dizziness, drowsiness, reduced judgment and motor skills. Caution in the elderly, orthostatic hypotension, asthenia, impaired liver and kidney function. Caution in patients with heart failure, conduction disturbances, cerebrovascular disease should be initiated and maintained at a low dose. Caution should be exercised in patients with a history of epilepsy, Parkinson's syndrome, and spasticity. Diabetic patients while using Risperidone need to closely monitor blood glucose levels. Do not use the drug Agirisdon for pregnant women; The drug Agirisdon should not be used by women who are breastfeeding; Do not drink alcohol during treatment with Agirisdon. Above is all information about the drug Agirisdon, uses and notes when using. Agirisdon is a prescription drug, patients or family members need to carefully read the instructions for use, strictly follow the doctor's instructions first to be effective when using and reduce side effects.