Uses of Anatin 300mg

Anatin 300mg is a psychotropic drug, commonly used in the treatment of epilepsy and neuropathic pain. To use the drug effectively, patients need to learn some information about the uses, dosage and note when using Anatin 300mg in the article below.

Anatin medicine 300mg is made in the form of hard capsules with the main ingredient is 300mg Gabapentin.
Gabapentin is an antiepileptic drug, the mechanism of action of which is currently unknown. In experimental animals, Gabapentin has an anti-extension effect after electric shock and it also inhibits seizures induced by Pentylenetetrazol.
The effectiveness of Gabapentin in the above experiment was similar to valproic acid but different from Phenytoin and Carbamazepine. Gabapentin's chemical structure is similar to that of a neurotransmitter inhibitor in our body, gamma-aminobutyric acid (GABA), but Gabapentin does not act directly on GABA receptors, nor does it act on GABA receptors. structural changes, levels of GABA release, metabolism, and withdrawal.
Anatin 300mg is indicated in the following cases:
Postherpetic neuralgia in adults. Partial seizures with or without secondary generalization in patients over 12 years of age with epilepsy. Anatin is also indicated for the adjuvant treatment of partial seizures in pediatric patients 3-12 years of age. Anatin 300mg drug is contraindicated in the following cases:
People who are sensitive to Gabapentin or to any component of Anatin. Caution when using Anatin 300mg:
If Anatin 300mg is discontinued and/or another antiepileptic drug is added, it should be done gradually over at least 1 week. Anatin 300mg should be used in nursing women only when the potential benefits outweigh the potential risks. There are not enough studies on the effectiveness of Anatin 300mg when used in pregnant women. Therefore, Anatin 300mg should only be used during pregnancy when absolutely necessary. Anatin 300mg may cause dizziness or drowsiness, so it may reduce your ability to drive or operate machinery safely. Therefore, you should not drive or operate machinery while taking Anatin 300mg. Caution when using Anatin 300mg drug with people with a history of mental disorders, people with impaired kidney function and hemodialysis. Anatin 300mg may cause a false positive in protein tests.

Anatin 300mg is used orally. The dosage of Anatin 300mg drug should be according to the prescription of a specialist, the reference dose in specific cases is as follows:
Anatin 300mg dose for epilepsy treatment in adults and children over 12 years old:
Dosage Anatin 300mg is effective 900mg/day, divided into 3 times. Dose adjustments to find an effective dose of Anatin 300mg can be done over 3 days as follows:

Anatin 300mg dose to treat epilepsy in children from 3 to 12 years old:
The effective dose of Anatin 300mg is 30mg/kg/day divided into 3 times, adjust the dose to find an effective dose of Anatin. can be carried out in 3 days as follows: Day 1: Take Gabapentin 10mg/kg/day. Day 2: Gabapentin dose 20mg/kg/day. Day 3: Gabapentin dose 30mg/kg/day. In a long-term clinical study, doses up to 40-50 mg/kg/day were also well tolerated. Anatin 300mg dose in the treatment of neuropathic pain in adults (from 18 years old):
The effective dose of Anatin 300mg is 900mg/day divided into 3 times. Dose adjustment to find an effective dose of Anatin can be done in 3 days, as follows.

Depending on the response, the dose of Anatin can be increased to 1800mg/day in 3 divided doses. Clinically, the therapeutic effect increased when using Anatin dose from 1800mg/day to 3600mg/day. Anatin 300mg dose for patients with impaired renal function: Due to the reduced clearance of Gabapentin in patients with impaired renal function, it is necessary to adjust the dose of Anatin based on creatinine clearance according to the following table:

Acute oral overdose of Anatin using the drug up to 49 grams has been reported. Anatin overdose symptoms include: Double vision, lethargy, slurred speech, coma and diarrhea. All patients with an overdose of Anatin recovered with supportive measures.
Gabapentin can be eliminated by hemodialysis, there are also some cases of overdose that do not require hemodialysis. Indications for color dialysis depend on the clinical condition or the patient's signs of severe renal impairment.

During the use of Anatin 300mg, you may encounter some side effects of the drug.
Common side effects of Anatin 300mg include:
Asthenia; Tired; Face covering; Hypertension; Anorexic; Flatulence; Gingivitis ; Purpura; Muscle pain; Dizzy ; Increased activity; Paresthesias; Decreased or lost reflexes; Jitter; Hostile behavior; Pneumonia; Epistaxis ; Shortness of breath; Stop breathing; Visual abnormalities. Rare side effects of Anatin 300mg include:
Allergies; Generalized edema; Weight loss; Chills; Anemia; Thrombocytopenia; Lymph node disease; Tendonitis ; Arthritis; Stiffness; Joint swelling; positive Romberg test; Use hair; Eczema; Dry skin; Increased sweating; Urticaria; Excessive hair growth; Excessive sebum secretion; Cysts; Herpes simplex; Blood in urine ; Difficulty urinating; Frequent urination; Cystitis; urinary retention; Urinary incontinence; Vaginal bleeding; amenorrhea; Menstrual disorders; Menorrhagia; Breast cancer; Inability to orgasm; Abnormal ejaculation; Cataract ; Conjunctivitis; Dry eyes ; Eyesore; Reduced eyesight. Rare side effects of Anatin 300mg include:
Dizziness; Tired; Alcohol intolerance; Unpleasant aftertaste; Hyperthyroidism ; Hypothyroidism; goiter; Reduce estrogen; Ovarian failure; Epididymitis ; testicle swelling; Manifestations similar to Cushing's syndrome; Increased white blood cells; Increased lymphocytes; Non-Hodgkin lymphoma ; Prolong bleeding time; Cartilaginitis - ribs; Osteoporosis; Inflammation of the synovial sac ; Muscle spasticity; Shingles; Skin discoloration; Skin rash; Sensitivity to light; Foot ulcers; Increased sebum secretion of the scalp; Psoriasis ; scaly; Caustic water; Skin nodules; Subcutaneous nodules; Melanoma; Skin gangrene; Local swelling; Kidney pain; White blood ; Itching of the genital area; Kidney stones; Acute renal failure; Anuria; Urinary tract; Kidney disease ; Nocturia; Pusuria; Urgent urination; Vaginal pain; Chest pain; Testicle pain. If you experience any side effects of Anatin, you need to immediately notify your doctor or go to a medical facility for timely support from medical staff.

Concomitant administration of Anatin with aluminum and magnesium-containing antacids may reduce the bioavailability of Gabapentin and decrease blood concentrations by 20%. If you need to use these two drugs, you should take Anatin at least 2 hours after the antacid. Anatin may increase the concentration of some oral contraceptives. Alcohol can make Anatin's side effects worse. When Anatin and Cimetidine are used together, it will change the renal excretion of both Gabapentin and Creatinine. However, the slight reduction in Gabapentin excretion by cimetidine is not clinically significant. Above is the basic information about Anatin 300mg for those who are interested in this drug. Please note, use Anatin 300mg medicine exactly as prescribed with the dose and time according to the doctor's notes to achieve the best effect.