Uses of Antipylo

Antipylo drug is indicated in the treatment of chronic stomach ulcers caused by HP bacteria, stomach ulcers when conventional anti-ulcer therapy is not effective... Let's learn about the uses, the precautions Note when using Antipylo through the article below.

“What is Antipylo?”. Antipylo drug contains active ingredients including 500mg of Clarithromtcin in the form of film-coated tablets, 500mg of Metronidazole in the form of film-coated tablets and 20mg of Omeprazole in the form of capsules. One box contains 7 blisters, each blister contains 6 pills including 2 Metronidazole tablets, 2 Clarithromycin tablets and 2 Omeprazol tablets.
The uses of each ingredient in Antipylo are as follows:
Omeprazole belongs to the group of drugs that inhibit the proton pump H + / K + ATPase of gastric parietal cells, thereby helping to limit the secretion of gastric acid. After stopping the drug, the gastric acid secretion returned to normal and there was no increased acid secretion; Tinidazole is an antibacterial antibiotic of the 5-nitroimidazole group. Acts against anaerobic bacteria, protozoa through the mechanism of entering microbial cells and causing damage on the DNA chain or inhibiting bacterial DNA synthesis; Clarythromycin is a new generation macrolide antibiotic, acting by binding to a specific site on the 50S ribosomal subunit of bacteria and inhibiting bacterial protein synthesis. The drug is indicated in the treatment of gastric ulcers caused by H. pylori bacteria, gastric ulcers when other methods of treating stomach ulcers are not effective.

Antipylo used to treat gastritis belongs to the group of prescription drugs, the dose used is prescribed by the doctor based on the patient's condition.
Some recommendations on Antipylo dosage are as follows:
Take 1 Omeprazole capsule before meals, 1 Clarithromycin tablet and 1 Tinidazole tablet after meals. Take the drug in the morning and evening; The usual duration of Antipylo treatment is 1 week;

Antipylo may cause some side effects as follows:
Gastrointestinal disorders: Vomiting, nausea, upset stomach, loss of appetite, taste abnormalities, flatulence, constipation, increased liver enzymes glimpse; Hypersensitivity reactions, urticaria, rash, pruritus; Headache, dizziness, and confusion may occur in some patients. Patients need to stop using the drug and notify the doctor if they experience any unwanted effects while taking Antipylo.

4.1. Contraindications Contraindicated to use Antipylo drug in the following cases:
Patients are sensitive to any component of Antipylo; Pregnant women; Patients with hematopoietic disorders. 4.2. Patients should be excluded the risk of malignancy before treatment with Antipylo, because the drug can mask the symptoms of the disease, delaying the diagnosis.
Caution should be exercised when using Antipylo in patients with renal impairment (creatinine clearance less than 30ml/min requires halving the therapeutic dose).
Do not use alcohol during treatment with Antipylo, because of the risk of causing a reaction of Disulfiram with the active ingredient Tinidazole in the drug
Long-term treatment with Atipylo can lead to overgrowth of fungi and bacteria bacteria are not sensitive to the drug. In case of superinfection, treatment should be discontinued and more appropriate therapy instituted.
In a small number of sick people, H. Pylori bacteria can become resistant to the antibiotics in the medicine.
For women who are breastfeeding: Antipylo treatment in this population should be prescribed and supervised by the treating physician based on the benefits and risks.
For drivers, operating machines: Antipylo does not affect the ability to drive or operate machines.
Store Antipylo at room temperature, away from sunlight and high humidity.

Drug interactions caused by Clarithromycin ingredients:
Clarythromycin increases the concentration of drugs that are metabolized via cytochrome P450 such as Triazolam, Warfarin, Disopyramid, Lovastatin, Cyclosporin, Phenytoin...; Clarythromycin increases the concentration of Theophylline in the blood plasma, so it is necessary to monitor the concentration of Theophylline in case of simultaneous use of two drugs; The potency of Digoxin is increased when used concomitantly with Clarithromycin, so it is necessary to monitor the concentration of Digoxin in the blood when used in combination; Clarithromycin reduces the rate of excretion of Carbamazepine, thereby increasing toxicity and increasing the risk of side effects; Clarithromycin has been shown to increase terfenadine concentrations; Concomitant use of clarithromycin and zidovudine in HIV-infected patients may decrease steady-state zidovudine concentrations. Drug interactions caused by Omeprazole:
The anticoagulant effect of Dicoumarol is increased when used with Omeprazole; Omeprazole reduces the elimination of Diazepam, Warfarin, Phenytoin. Drug Interactions Caused by Tinidazole: Alcohol increases the risk of disulfiram-like reactions during treatment with Tinidazole, so do not use alcohol during treatment with this medicine.
Drug interactions occur that increase the risk of having an effect and reduce the therapeutic effect of Antipylo, so to ensure safety and effectiveness in treating patients, it is necessary to inform the doctor about drugs and foods. were using before taking Antipylo.