Uses of Axoplatin


Axoplatin medicine has the main active ingredient is Oxaliplatin with the strength of 50mg and other excipients in sufficient quantity. This is a drug that treats cancer and affects the immune system.

1. What is Axoplatin?


What is Axoplatin? Axoplatin medicine has the main active ingredient is Oxaliplatin with a strength of 50mg and other excipients in sufficient quantities. This is a drug that treats cancer and affects the immune system.
Axoplatin is prepared in the form of lyophilized powder mixed with solution for intravenous infusion. Packing is a medicine box containing 1 bottle of 50mg
Effects of active ingredient Oxaliplatin:
Stopping agent (L: cancer treatment drug- immunosuppressant drug-platinium). Main active ingredient Oxaliplatin is an anti-neoplastic agent belonging to the new class of platinum compounds. In it, atomic platinum forms a complex with 1,2-diaminocyclohexane (“DACH”) and an Oxalate group.
Oxaliplatin has a broad spectrum of action in vitro causing cytotoxicity and in vivo has antitumor activity against a variety of tumors including colorectal tumors. The synergistic phenomenon of cytotoxic activity between Oxaliplatin and 5-fluorouracil in both in vitro and in vivo. Oxaliplatin has also shown its in vitro and in vivo activity against cisplatin-resistant cancers.

2. Effects of Axoplatin


Axoplatin is used in the treatment of gastrointestinal cancers such as colon cancer (in combination with 5-fluorouracil and folinic acid drugs).

3. Usage and dosage of Axoplatin


Usage and dosage of Axoplatin as follows:
3.1. Usage of Axoplatin Drug Axoplatin is prepared in the form of lyophilized powder for infusion, suitable for intravenous use. Drug preparation and intravenous administration should be performed by qualified medical personnel. 3.2. Dosage of the drug Axoplatin Dosage for adults: 85 mg/m2 body, intravenous infusion over a period of 2 to 6 hours in 250-500 mL of 5% glucose, every 2 weeks; The adjustment of the therapeutic dose should be prescribed by the doctor, according to tolerability; always infuse the drug containing the active ingredient Oxaliplatin before using 5-fluorouracil.

4. Undesirable effects of the drug Axoplatin


During the use of Axoplatin, users may experience some unwanted effects, specifically as follows: gastrointestinal disorders, hematopoietic disorders, sensory neuropathy, sensory disturbances oropharyngeal region, allergic reactions, causing increased toxicity to the ears and kidneys.
Usually the side effects or unwanted effects of Axoplatin will go away when the drug is stopped. In the event that your body appears more rare side effects that are not mentioned in the instruction sheet, you need to take the initiative to notify your doctor immediately.

5. Some notes when using Axoplatin drug


During the use of Axoplatin, patients should pay attention to the following issues:
5.1. Axoplatin is contraindicated in the following cases:
People with hypersensitivity or hypersensitivity to the active ingredient Oxaliplatin or any of the excipients contained in the drug's ingredients. Women who are breastfeeding. People with myelosuppression: neutrophils Other cases are not allowed to use drugs as prescribed in the drug leaflet or prescription of the treating doctor. Contraindications of Axoplatin must be understood as absolute contraindications, that is, not for any reason that contraindications can flexibly use this drug.
5.2. Notes and precautions when using Axoplatin Take precautions when using Axoplatin in the following cases:
Only use Axoplatin in oncology. Before using the drug, you should have a neurological examination before and after each use. At the same time, drug users need to perform a blood count test before treatment. The subjects to note before taking Axoplatin: the elderly, pregnant women, lactating women, children under 15 years old, people with liver failure, kidney failure, people with myasthenia gravis, hepatic coma or inflammation stomach ulcers . Using Axoplatin during pregnancy: You need to carefully consider and consult your doctor before taking the drug. Drugs including Axoplatin, even though they have been tested, still have risks when used. Use of Axoplatin during lactation: Mothers need to carefully weigh the benefits and risks for mother and baby. Do not arbitrarily use this drug without carefully reading the instructions for use and instructions of the doctor to protect the health of both mother and baby Above is all information about Axoplatin medicine, patients need Read the instructions for use carefully, consult your doctor/pharmacist before use. Absolutely do not arbitrarily buy Axoplatin to treat the disease at home, because there may be unwanted side effects to health.
Follow Vinmec International General Hospital website to get more health, nutrition and beauty information to protect the health of yourself and your loved ones in your family.

9 lượt đọc

Dịch vụ từ Vinmec

Bài viết liên quan