Uses of Axorox

Axorox is often prescribed to treat common bacterial infections related to the respiratory tract, skin, soft tissues, urinary tract, ... To ensure early effective treatment and prevention. To maximize the risk of adverse side effects, the patient should strictly follow the regimen prescribed by the doctor.

Axorox belongs to the group of antifungal, antiparasitic and anti-infective drugs. The drug is often used for infections of the urinary tract, ear - nose - throat, mouth, skin or soft tissue. Axorox medicine originated from India, is made in the form of film-coated tablets and packed in boxes of 10 blisters x 10 tablets.
Each Axorox tablet contains the active ingredient Roxithromycin 150mg. In addition, the manufacturer also adds other excipients that play an auxiliary role and increase the use of the active ingredient Roxithromycin in the drug.

2.1 Uses of the active ingredient Roxithromycin Roxithromycin in Axorox acts as a semi-synthetic antibiotic belonging to the Macrolide family. In terms of pharmacokinetic properties, Roxithromycin has a good ability to penetrate into all compartments as well as cells in the body. Concentrations of Roxithromycin are particularly high in the tonsils, lungs, prostate, sinuses, and uterus. However, this active substance is not able to cross the blood-brain barrier. Most of Roxithromycin is eliminated and metabolised in the liver, then excreted in the bile and feces. Therefore, the drug can be used at the usual dose for patients with renal insufficiency.
According to research, the active ingredient Roxithromycin in Axorox has antibacterial effect against the following strains of bacteria:
Highly susceptible bacteria: Campylobacter coli, Campylobacter jejuni, Bordetella pertussis, Clostridium perfringens, Chlamydia trachomatis, Enterococcus, Gardnerella vaginalis, Mobiluncus, Mycoplasma pneumoniae, Porphyromonas and Propionibacterium acnes,... Medium sensitive bacteria: Ureaplasma urealyticum, Haemophilus influenzae or Vibrio cholerae. Drug-resistant bacteria: Bacteroides fragilis, Enterobacteriaceae, Acinetobacter spp. Fusobacterium, Nocardia, Pseudomonas spp, Mycoplasma hominis or Meti-R Staphylococcus. 2.2 Indications and contraindications to the use of Axorox At present, Axorox is prescribed by doctors to treat the following specific bacterial infections:
Treatment of ear, nose and throat infections, including tonsillitis , otitis media, pneumonia, esophagitis, chronic bronchitis, sinusitis or bronchitis. Treatment of urinary and genital tract infections, including prostatitis, urethritis, vaginitis, cervicitis, salpingitis, especially inflammatory conditions caused by Chlamydia strains. Treatment of oral infections. Treatment of skin-soft tissue infections, including boils, cystitis, toxic boils, pyoderma, impetigo, erysipelas, infectious dermatitis or ulcerative colitis. As recommended by the doctor, it is necessary to avoid self-administering Axorox for the following patients without indication:
Patients with a history of hypersensitivity or allergy to the active ingredient Roxithromycin or any auxiliary excipients included in drug formulations. Axorox is contraindicated in patients with hypersensitivity to macrolide antibiotics. Axorox should not be used in patients who are concurrently taking ergotamine-like vasoconstrictor compounds. Axorox and certain other macrolide antibiotics are contraindicated in patients being treated with Astemizol or Terfenadine because of the risk of serious life-threatening arrhythmias. Axorox is contraindicated in patients being treated with cisapride due to the risk of severe arrhythmias. Axorox should not be used in pediatric patients under 6 months of age. Relative contraindications to the use of Axorox for pregnant women or nursing mothers.

Axorox is made in the form of film-coated tablets, for oral use. Patients should take Axorox whole tablets with a glass of water about 250ml, avoid taking with carbonated drinks, beer, wine, coffee or other stimulants. During the treatment of infections with Axorox, patients need to adhere to the exact recommended dosages below:
Dosage for adults: Take a daily dose of 150mg x 2 times / day or 300mg / time / day before eating. Axorox should be taken for a minimum of 2 days after symptom relief and for at least 10 days for streptococcal infections, vaginitis, cervicitis or urinary tract infections. Treatment of bacterial infections with Axorox can last up to 4 weeks. Dose for children: Take a dose of 5-8mg/kg body weight/day, divided into 2 times/day. For children weighing from 6-11kg can take a dose of 25mg x 2 times/day, children weighing 12 - 23kg take a dose of 50mg x 2 times/day, children weighing from 24-40kg take a dose of 100mg x 2 times/day. Patients with severe hepatic impairment: It is necessary to reduce the dose of Axorox to half of the usual dose. Dosage for Patients with Renal Impairment: No dose modification of Axorox is required. Before treatment with Axorox, patients should carefully read the instructions for use or follow the instructions of the doctor. Absolutely do not arbitrarily apply, change the dose or extend the time of taking the drug beyond the prescribed time without discussing with the medical person in charge.

In certain cases, patients may experience adverse effects when treating infections with Axorox, specifically:
Common reactions: Vomiting, nausea, diarrhea or upper pain taste . Uncommon reactions: Rash, angioedema, urticaria, bronchospasm, purpura, anaphylaxis, headache, dizziness, vertigo, decreased sense of smell, paresthesia, decreased taste, multiple infection or proliferation of drug-resistant strains of bacteria. Rare reactions: Cholestatic hepatitis, elevated serum liver enzymes or symptoms of pancreatitis. Some adverse side effects may gradually disappear when the patient stops treatment. However, some rare symptoms have the risk of progressing to other complications and need to be treated promptly to avoid endangering the patient's life. Ideally, if any side effects occur during the use of Axorox, the patient should notify the doctor as soon as possible for support.

Before and during the use of Axorox, patients need to note some important things below:
Caution when treating patients with Axorox with severe liver or kidney failure. Caution should be exercised when prescribing Axorox to the elderly, people with hypersensitivity to drugs, suspected pregnancy, peptic ulcers, hepatic coma or myasthenia gravis. The use of Axorox with alkaloids should be avoided due to the risk of vasoconstriction of ergot (Dihydroergotamine or Ergotamine). Avoid combining Axorox with drugs such as Terfenadine, Midazolam, Disopyramide, Digoxin, Astemizol and Cisaprid due to the risk of serious arrhythmias. Axorox has little interaction with Carbamazepine, Warfarin, Ciclosporin or oral contraceptives. Taking Axorox with Ciclosporin and Theophylline may slightly increase plasma concentrations of these drugs. Axorox may increase serum concentrations of unbound Disopyramide. Axorox has the potential to increase plasma concentrations of Bromocriptine. There is currently no specific antidote for Axorox overdose. Therefore, if symptoms of overdose appear, the patient can be treated with gastric lavage and supportive treatment. Carefully check the expiry date of Axorox before use, and carefully check the medicine for strange signs such as discoloration, deformation or mold. Above is all information about Axorox drug, patients need to carefully read the instructions for use, consult a doctor / pharmacist before using. Note, Axorox is a prescription drug, patients absolutely must not buy and treat at home because they may experience unwanted side effects.