Uses of Clarividi 250

Clarividi is an antibiotic that fights infections. The drug is used in pathologies caused by bacterial infections. Let's learn about the uses, usage and things to keep in mind when using Clarividi through the article below.

Clarividi 250 contains the antibiotic Clarithromycin 250mg as the main ingredient. It is available in the form of long film coated tablets.
Clarithromycin is a semi-synthetic antibiotic from erythromycin, belonging to a new generation of macrolides. The structural change of this drug compared to erythromycin allows clarithromycin to extend the antibacterial spectrum, increase drug concentrations in tissues, improve stability in acidic media, increase bioavailability, and help reduce its effects. side effects on the digestive system.
The antibacterial mechanism of clarithromycin is due to binding to a specific site on the 50s ribosomal subunit of susceptible bacteria, thereby inhibiting bacterial protein synthesis. Clarithromycin is highly effective against gram-positive and gram-negative, aerobic and anaerobic bacteria including: Staphylococcus aureus (staphylococci); Streptococcus pyogenes (group A hemolytic streptococcus); Streptococcus pneumoniae (pneumococcal); Streptococcus agalactiae; Listeria monocytogenes, Hemophilus influenzea; Hemophilus para influenzea; Moraxella (Branhamella) catarrhalis; Neisseria gonorrhaee; Helicobacterpylori...
After taking the drug Clarithromycin is rapidly and extensively absorbed from the gastrointestinal tract. Distributed in many organ tissues at high concentrations, the half-life of clarithromycin is approximately 3-4 hours after 250 mg twice daily dosing and about 5-7 hours in patients receiving 500 mg twice daily. /day.

Thanks to the antibacterial effect of the drug, it is indicated in the following cases:
Tonsillitis, otitis media, acute sinusitis, acute bronchitis, exacerbation of chronic bronchitis, inflammation of the skin and soft tissues. Pneumonia caused by Mycoplasma pneumoniae and Legionella, diphtheria, the first stage of patients infected with pertussis, opportunistic infections caused by Mycobacterium. Combination in monotherapy for eradication of Helicobacter pylori in peptic ulcer.

Usage: The drug is taken orally and taken after meals.
Dosage:
Adults:
The usual dose is 250mg/time and twice daily for 7 days, or 500mg once/day. In severe infections the dose may be increased to 500 mg twice daily, or 1000 mg once daily for 14 days. Children over 12 years: Use the same drug as adults.
Children under 12 years old:
Daily dose for children under 12 years old is 7.5 mg/kg, 2 times a day, maximum dose is 500 mg/day. The duration of treatment is usually 7-10 days depending on the strain and severity of the disease. Treatment of pharyngitis caused by group A streptococcus requires at least 10 days. In combination in H. pylori eradication regimens in patients with duodenal ulcer: Adults: The usual dose of clarithromycin is 500 mg twice daily for 7 days, accompanied by antibiotics Amoxicillin 1000 mg once and twice daily, omeprazole 20 mg orally 2 times daily.
Elderly: Use the same dose as adults.
Renal impairment:
No dosage adjustment is usually required unless the patient has severe renal impairment (creatinine clearance less than 30ml/min). If dose adjustment is required, the total daily dose should be halved.

Clarividi is contraindicated in the following patients:
People with a history of increased hypersensitivity to macrolide antibiotics. Clarithromycin should not be used with ergot derivatives. Concomitant use of clarithromycin with any of the following drugs is contraindicated: cisapride, pimozide and terfenadine. Increased concentrations of cisapride, pimozide and terfenadine have been reported in patients receiving these drugs and clarithromycin concomitantly. This can cause QT prolongation and arrhythmias, including ventricular tachycardia, ventricular fibrillation, and torsades de pointes. Pregnant and lactating women

In general, the antibiotic clarithromycin is well tolerated, with few side effects. However, for some people there is still a risk of side effects:
Commonly reported side effects include: nausea, vomiting, dyspepsia, diarrhea and abdominal pain. Stomatitis , glomerulitis and abnormal granulation of the mouth Other side effects: headache, allergic reactions ranging from urticaria, mild skin rash to more severe anaphylaxis and, rarely, syndrome Stevens-Johnson. Taste disturbances may occur. Reversible loss of color in the tongue, and a decrease or loss of hearing may be reversible upon discontinuation of the drug. Pseudomembranous colitis has been reported with the drug but is rare and can range from mild to life-threatening. Liver dysfunction is usually reversible, but liver dysfunction can be severe and fatal liver failure has been reported very rarely. There have been reports of some transient central nervous system side effects: anxiety, dizziness, insomnia, hallucinations, psychosis, nightmares and confusion. When experiencing side effects of the drug, you should notify or go to a medical facility immediately for advice and treatment.

Antibiotics are used under the doctor's prescription, you should avoid taking them unless prescribed and there is no infection. Inform your doctor about your medical and allergy history before use.
To limit the risk of antibiotic resistance, you should take this medicine exactly as prescribed, do not arbitrarily stop the drug when it is not enough time.
Prolonged and repeated use of clarithromycin can also cause the growth of fungi or bacteria that are no longer susceptible to the drug. If superinfection occurs during administration, clarithromycin should be discontinued and appropriate therapy instituted. Clarithromycin is excreted mainly by the liver and kidneys, so caution should be exercised when using this antibiotic in patients with impaired hepatic or renal function.
Drug interactions: Due to the simultaneous use of drugs can lead to increased effects, decreased effects or increased risk of toxicity to the body. So before taking it, tell your doctor about all the medicines you are taking. Especially drugs such as drugs that are metabolized by the cytochrome P450 system (anticoagulants warfarin, ergot alkaloids, blovastatin, triazolam, disopyramide, phenytoin and cyclosporin); carbamazepine; zidovudine...
Storage:
Keep the medicine in a closed container, in a cool dry place, away from direct light. Keep medicine out of reach of children. Do not use if the medicine has expired or shows signs of deterioration.
Above is the information about the drug Clarividi 250mg, this is an antibiotic that only works on bacterial infections and has no effect on viruses. So that you do not abuse drugs, avoid causing drug resistance and affecting the body.