Uses of Euzimnate


Euzimnat is a second generation cephalosporin antibiotic. The drug has the main ingredient is Cefuroxime, the content of 500mg has anti-infective effect, treating cases of nasopharyngitis, sinusitis, pneumonia, pyelonephritis, ... To understand the details of the drug use as well as instructions. How to prescribe and how to use Euzimnat? You can refer to the article below.

1. Euzimnate drug effect

The active ingredient Cefuroxime in the drug is a broad-spectrum semi-synthetic antibiotic, belonging to the cephalosporin group, with antibacterial activity due to inhibition of bacterial cell wall synthesis by binding to essential target proteins. The drug has effective antibacterial activity against many common pathogens, including beta-lactamase/cephalosporinase-producing strains of both gram-positive and gram-negative bacteria and is particularly resistant to many beta-lactamase enzymes of gram negative bacteria.
After oral administration, Euzimnat is absorbed from the gastrointestinal tract and rapidly hydrolyzed in the intestinal mucosa and in the blood to release the drug Cefuroxime into the systemic circulation.
Euzimnat is best absorbed when taken with a meal, or immediately after a meal, and has a serum half-life of 1 to 1.5 hours.
The drug is not metabolized and is eliminated by glomerular filtration and tubular secretion.
Euzimnat is indicated for use in the following cases:
Otitis media, sinusitis, tonsillitis, laryngitis, pharyngitis, pneumonia, acute bronchitis, exacerbation of chronic bronchitis. Pyelonephritis, cystitis Urethritis Boils Dermatitis, impetigo Typhoid fever Gonorrhea Acute gonorrhea urethritis Acute cervicitis Contraindicated using Euzimnat for patients who are allergic to cefuroxime components or group of Cephalosporins or other excipients contained in the drug.

2. Dosage - How to take Euzimnat


2.1. How to use Euzimnat should be used exactly as prescribed by a specialist. The drug is used in batches from 5-10 days, then re-evaluate the disease, if it does not improve or worsen, it is necessary to notify the doctor to adjust the drug.
Euzimnat should be taken with a meal or immediately after a meal.
2.2. Dosage Dosage for adults:
For most infections: oral dose of 250mg x 2 times/day. Typhoid fever: oral dose of 500 mg x 2 times/day. Infections of the urinary system - genitourinary: Oral dose of 125mg x 2 times/day. Mild to moderate lower respiratory tract infections: Oral dose of 250mg/time x 2 times/day. Severe respiratory infections or suspected pneumonia: Take 500mg/time x 2 times/day. Pyelonephritis: Oral dose of 250mg / time x 2 times / day. Uncomplicated gonorrhea: Take a single dose of 1g. Early stage Lyme disease: Oral dose of 500mg x 2 times / day, the course of use for 20 days. Dosage for children:
In case of infection: Oral dose of 125mg/time x 2 times/day, maximum dose of 250mg/time. Typhoid fever: Take 250mg/time x 2 times/day. Middle ear infection or serious infection: Take 250mg/time x 2 times/day. Dosage is for reference only, the specific dose depends on the patient's body condition, age, weight, and medical condition, the dose can be adjusted to suit the patient.

3. Side effects when taking Euzimnat


When taking Euzimnat, you may experience the following side effects:
Erythema, toxic skin necrosis, skin rash, papules, itching, urticaria, fever, diarrhea, nausea, vomiting Eosinophils Elevated liver enzymes Inflammation pseudomembranous bowel Decrease of white blood cells, platelets.

4. Overdose/forgotten dose of Euzimnat


When taking an overdose of Euzimnat you may experience the following symptoms: gastrointestinal disturbances, nausea, vomiting, and diarrhea, a stronger reaction causing increased neuromuscular excitability and the appearance of convulsions, especially in patients with renal failure.
Treatment of overdose: First of all, it is necessary to protect the patient's respiratory tract, support ventilation and infusion. If there is a risk of seizures, discontinue Euzimnat immediately and initiate anticonvulsant measures when clinically indicated. Finally, hemodialysis makes it possible to remove drugs from the blood, but most treatment for drug overdoses is supportive or symptomatic. Note: To the possibility of overdose of many drugs due to their interactions with each other.
When you forget a dose of Euzimnat you need to take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue taking it as scheduled. Note: Patients are not allowed to make up for the missed dose on their own.

5. Euzimnat drug interactions with other drugs


Need to pay attention to the following drug interactions with Euzimnat to avoid causing serious consequences:
Ranitidine, sodium bicarbonate when combined with Euzimnat reduces the bactericidal effect of the drug. Antacids or H2 blockers when used concurrently with Euzimnat will increase gastric acid. Therefore, doctors recommend taking Euzimnat after 2 hours. High-dose probenecid when combined with Euzimnat reduces renal clearance. Aminoglycosides interact with Euzimnat to increase the toxicity of the drug in the kidneys. Euzimnat is an antibiotic that works to treat bacterial infections: rhinosinusitis, pneumonia, urinary tract infections,... To ensure the safe use of Euzimnat, the correct indications and the right dose. You need to consult your doctor/pharmacist. Absolutely do not arbitrarily buy drugs to treat at home because of possible side effects, dangerous drug interactions.

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