Uses of Exjade 500

Exjade 500 contains the main ingredient Deferasirox with the effect of removing excess iron from the body to reduce iron excess. So how should Exjade 500 be used?

1. What is Exjade 500?

Exjade 500 is a medicine containing the active ingredient Deferasirox. This is also known as a chelation drug, which is used to remove excess iron from the body in patients with iron overload. The drug works by trapping and removing excess iron and then excreted mainly in the feces.

2. What are the effects of Exjade 500?

Exjade 500 is indicated for use in the following cases:
Patients in the process of blood transfusion many times may cause an excess of iron in the body. People with non-transfusion-dependent anemia may also experience a cumulative iron overload that increases over time. This is mainly due to the body's increased absorption of dietary iron in response to low blood cell counts. Treatment of chronic iron excess due to frequent blood transfusions in beta-hemolytic anemia patients with low red blood cell counts and counts aged 6 years and older. Treatment of chronically high iron levels where treatment with deferoxamine is not effective in people with beta-hemolytic anemia. Indicated for use are patients with other diseases and in children from 2 to 5 years old.

3. How to use Exjade 500

Excessive iron excess in adults and children over 2 years old
Initial dose is 20mg/kg body weight orally once a day Maintenance dose is about 20-40mg/kg body weight orally once a day Maximum use with 40 mg/kg body weight orally once a day. Adults and children over 2 years old with thalassemia anemia
Initial dose with 10mg/kg body weight orally once a day.

4. Contraindications to using Exjade 500

Some contraindications to using Exjade 500 include:
Allergy to deferasirox or any other ingredient of the drug. You need to report to your doctor about your allergy to get the appropriate treatment. Patients with moderate or severe kidney disease. The patient is taking any other iron-chelating drugs.

5. Some side effects when taking Exjade 500

Some unwanted side effects may be encountered when using the drug such as:
Shortness of breath, dizziness, swelling of the face and throat, vomiting blood or appearance of black stools. In addition, patients may develop drowsiness, abdominal pain, jaundice or yellow eyes with dark urine. Gastrointestinal disturbances occurring after eating or drinking When any of the above symptoms appear, the patient should stop using the drug and contact a doctor immediately.

6. Interactions between Exjade 500 and other drugs

Some medications can interact when used with Exjade 500, including:
Medicines that regulate high levels of iron in the body An antacid for heartburn that contains aluminum. Cephalosporin antibiotics Anticoagulants. The hormonal contraceptives Bepridil, ergotamine (used for heart problems and migraines). Repaglinide (used to treat diabetes). TB medicine Rifampicin Therefore, it is necessary to inform your doctor about all medicines that you are taking to avoid unfortunate reactions.
In addition to the above information, if in the process of taking Exjade 500, the patient has any problems, they can contact the prescribing doctor for the most specific advice.

Reference source: youmed.com

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