Uses of Januvia

Januvia medicine is made in the form of tablets, with the main ingredient being Sitagliptin monohydrate phosphate. The drug is indicated as monotherapy, in combination with other drugs, to control blood sugar in patients with type 2 diabetes.

Januvia medicine has the following strengths: Januvia 100mg, Januvia 50mg, Januvia 25mg. The article mainly refers to the drug form Januvia 100mg content.

Januvia medicine contains the active ingredient Sitagliptin - a component of the DPP-4 enzyme group, which helps reduce blood sugar levels in patients with type 2 diabetes. The drug helps increase insulin levels produced after a meal, while reducing the amount of sugar produced by the body. Januvia can be used alone or in combination with certain other medications (insulin, metformin, sulphonylurea or gitazone) to lower blood sugar levels, in conjunction with an exercise and diet plan. science.
Do not use Januvia if the patient is allergic to sitagliptin or other ingredients in the medicine.

Usage : Oral. Patients can take Januvia 100mg with or without food.
Dosage : Exactly as prescribed by the doctor:
Usual recommended dose: 1 tablet of 100mg/time/day; Patients can take the drug alone or in combination with some drugs that lower blood sugar (as prescribed by the doctor). Dosage in patients with renal impairment: Renal function should be assessed before treatment and then periodically checked:
Mild renal impairment: CrCl ≥ 50mL/min: No dose adjustment is required; Moderate renal failure: CrCl 30 - 50mL/min: Use the drug at a dose of 50mg/day/time; Severe renal failure: CrCl < 30 mL/min or end stage requiring peritoneal dialysis, hemodialysis: 25mg/day/time. It is important that during the course of taking the drug, the patient needs to maintain a suitable diet and exercise.
Overdose: In case of emergency or overdose, the patient should call 911 immediately or go to the nearest hospital for timely treatment.
Missed dose: When forgetting to take a dose of Januvia, the patient should take it as soon as he remembers. If it is almost time for your next dose, skip the missed dose and continue with your usual dosing schedule.

When using Januvia 100mg, patients may experience some side effects such as:
Severe, persistent pain in the abdomen (stomach), which may spread to the back, with or without nausea. and vomiting. This is a sign of pancreatitis; Serious allergic reactions: Rash, hives, skin abrasions, blisters on the skin, swelling of the face, throat, lips, tongue causing difficulty breathing, swallowing. In this case, the patient should stop taking the drug immediately and notify the doctor immediately. The doctor may prescribe an allergy medication and an alternative medicine to treat diabetes; Side effects when combining sitagliptin (a component of the drug Januvia) with metformin: Low blood sugar (hypoglycemia), flatulence, nausea, vomiting, stomach pain, drowsiness, diarrhea, constipation, feeling upset stomach; Side effects when combining sitagliptin with sulphonylurea and metformin: Low blood sugar (hypoglycemia), constipation; Side effects when combining sitagliptin with pioglitazone: Bloating, swelling of the hands or feet; Side effects when combining sitagliptin with pioglitazone and metformin: Swelling of the hands or feet; Side effects when combining sitagliptin with insulin (with or without metformin): Flu, dry mouth; Side effects when using sitagliptin alone or in combination with other diabetes medications: Low blood sugar (hypoglycemia), upper respiratory tract infection, nasal congestion, runny nose, headache, sore throat, osteoarthritis, arm or leg pain, itchy skin, constipation, kidney problems (requiring dialysis), vomiting, muscle pain, joint pain, back pain, etc.

Before and while taking Januvia 100mg, patients should note:
There is a risk of pancreatitis when using Januvia. Pancreatitis is a serious medical condition that can be life-threatening. Patients should stop taking the medicine and tell their doctor right away if they have severe and persistent stomach pain, with or without vomiting because it is possible that you have pancreatitis; Patients taking Januvia may experience a skin reaction called bullous pemphigus . Should tell your doctor if you develop blisters or cracked skin (slippery skin) for appropriate advice; People under 18 years of age should not use Januvia because the effectiveness and safety of the drug has not been evaluated in children and adolescents; No dose adjustment of Januvia is required in the elderly because in studies, Januvia was effective and well tolerated by the elderly; Januvia should be used with caution in pregnant women and nursing mothers, and should consult a doctor; Symptoms of dizziness and drowsiness or low blood sugar may be experienced in people taking Januvia. Therefore, patients taking the drug should be careful when driving or operating machinery. Januvia 100mg is used as an adjunct to diet and exercise to better control blood sugar in patients with type 2 diabetes. Before using Januvia, patients should inform their doctor about any medical conditions. The patient is not allowed to increase or decrease the dose of the drug to avoid unpredictable side effects.