Uses of Lusazyme

Lusazym drug has the main active ingredient is Trimetazidine Dihydrochloride with the corresponding concentration of 20mg and other excipients in sufficient quantities. This is a drug that is used in the prevention of angina, treatment of retinal vascular lesions,...

What is Lusazym? Lusazym drug has the main active ingredient is Trimetazidine Dihydrochloride with the corresponding strength of 20mg and other excipients in sufficient quantities. This is a drug used in the prevention of angina, treatment of retinal vascular lesions,...
Lusazym drug is prepared in the form of film-coated tablets, suitable for direct oral use. . Packing is a medicine box with 2 blisters and each blister contains 10 tablets.
1.1. Pharmacokinetics of the main active ingredient Trimetazidine Main active ingredient Trimetazidine is the only antianginal and anti-ischemic agent in the new class of compounds with anti-ischemic action without causing any blood changes action, and improve myocardial ischemia. The drug works to treat angina through a direct cytoprotective action on the myocardium, thereby avoiding undesirable effects such as left ventricular insufficiency, excessive peripheral vasodilation and other adverse effects. when treated with antianginal drugs. 1.2. Pharmacokinetics of the active substance Trimetazidine The main active ingredient Trimetazidine is rapidly absorbed, with a peak in plasma occurring about 2 hours after dosing. Absolute bioavailability is more than 85%. Maximum plasma concentrations are approximately 85 ng/ml following a single oral dose of 40 mg trimetazidine. The main active ingredient Trimetazidine is eliminated mainly in the urine; mean half-life is 5.5 hours. 1.3. Effects of the active ingredient Trimetazidine Main active ingredient Trimetazidine stabilizes the energy of cells in the state of systemic hypoxia or ischemia. The drug suppresses the electrophysiological manifestations of ischemia.
In the presence of the active ingredient trimetazidine, the intracellular acidosis caused by ischemia is greatly reduced and rapidly returns to near normal.
Pharmacokinetics Trimetazidine reduces the toxicity of oxidized free radicals in cellular ischemia. Therefore, Lusazym has a protective effect on cells against tissue hypoxia.
These properties are proportional to the degree of tissue hypoxia and are independent of sympathetic activation.

Lusazym drug is used in the treatment of specific diseases as follows:
For the cardiovascular system, prophylactic treatment of angina. For the eyes: treatment of damage to blood vessels in the retina. For otolaryngology treatment of vasomotor vertigo, Ménière's syndrome, tinnitus.

3.1. How to use Lusazym Lusazym drug is prepared in the form of film-coated tablets, suitable for direct oral use. Time to take medicine at the beginning of meals. 3.2. Dosage of Lusazym Dosage for treatment of eye and ear diseases: Daily dose of 40 mg - 60 mg tablets, divided into 2 to 3 times orally. Dosage for treatment of coronary insufficiency, angina: The dose is 20 mg x 3 times a day, then it can be reduced to 20 mg x 2 times/day.

During the use of Lusazym, patients may experience some side effects as follows:
Besides the therapeutic effects of the drug, during treatment with Lusazym, there may also be some problems. Undesirable effects, specifically as follows: Headache, skin rash, nausea, upset stomach, loss of appetite, increased liver enzyme index. However, side effects are usually mild and nonspecific. The above does not include all the unwanted effects and other side effects that may also occur during use. You need to pay attention to actively notify the treating doctor for medical advice about adverse effects when using Lusazym.

Interactions of Lusazym drugs that may occur during use are as follows:
According to current studies, there have been no interactions with any drugs. Trimetazidine is not an inducer, nor is it an inhibitor of hepatic drug-metabolizing enzymes, and as such it is unlikely that Trimetazidine will interact with many drugs metabolized in the liver. Patients still need to be carefully monitored when combining Lusazym with another drug. You need to take the initiative in telling your treating doctors or clinical pharmacists about the herbal products or health foods, prescription and over-the-counter medicines you are taking. used to minimize adverse drug interactions that may cause unwanted effects on the health of the user. Interactions of Lusazym with food and drink: When using this drug with foods or alcohol, beer, tobacco... because in foods and beverages containing other active ingredients, May cause antagonism or synergistic effects with the drug. You need to actively read the instructions for use of Lusazym carefully or consult your treating doctor about how to use Lusazym with foods, drinks containing alcohol or smoking.

6.1. Contraindications of the drug Lusazym: People with sensitive or hypersensitivity to drug components, heart failure, cardiovascular collapse. Contraindications of the drug Lusazym are absolute contraindications, that is, in any case, these contraindications cannot be flexible in the use of the drug. To ensure the effectiveness of treatment, it is best for the user of the drug to strictly follow the instructions of the treating doctor about the dose and how to use it. 6.2. Notes and precautions of the drug Lusazym Caution when using Lusazym drug with the elderly. Do not use Lusazym drug with pregnant and lactating women. Effects of Lusazym on the ability to drive and use machines: No significant effects. Store Lusazym in a dry place, at a temperature of 15 - 30 degrees Celsius in tightly closed packages, away from moisture and away from direct light. Besides, it is necessary to store Lusazym medicine out of the reach of children and family pets. Absolutely do not use the drug Lusazym when it has expired, is watery, distorted, or has signs of chemical change. Consult with environmental protection companies for how to dispose of drugs. Never throw away or flush the medicine down the toilet or plumbing. Lusazym drug has the main active ingredient Trimetazidine Dihydrochloride with the corresponding concentration of 20mg and other excipients in sufficient quantities. This is a drug that is used in the prevention of angina, treatment of retinal vascular damage, ... When prescribed by a doctor, patients should carefully read the instructions for use on the leaflet. drug information, consult the treating doctor/clinical pharmacist before using the drug. Absolutely do not arbitrarily buy Lusazym to treat the disease at home, because there may be unwanted side effects to health.
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