Uses of Masak

With the main ingredient is Calcitriol, Masak medicine is used to treat and prevent osteoporosis, rickets, osteomalacia and osteodystrophy in some special groups.

Masak belongs to the group of vitamins and minerals, with the main ingredient being Calcitriol with a content of 0.25mcg. Calcitriol creates an environment for intestinal calcium absorption and regulates bone mineralization. Calcitriol also has the effect of regulating calcium homeostasis and stimulating bone formation.
Masak medicine is made in the form of soft capsules and is indicated for use in the following cases:
Treatment and prevention of osteoporosis in women after menopause. Treatment of rickets and osteomalacia (rickets responsive or resistant to vitamin D, rickets with decreased blood phosphate levels). Treatment of hypothyroidism (primary, postoperative, or pseudohypothyroidism). Treatment of osteodystrophy in patients with chronic renal failure (especially patients on hemodialysis).

Masak medicine is taken orally. The patient should take the tablet whole with water. Depending on the patient's response, the doctor will adjust the dose accordingly to avoid hypercalcemia. Therefore, patients need to consult a doctor to be prescribed a dose to achieve effective treatment. At the same time, the patient needs to take Masak medicine fully and regularly every day, and at the same time, it is necessary to change the diet and strengthen the preparation in case of need.
Dosage is carefully determined depending on the serum calcium concentration of the patient. During the course of taking Masak, patients should have their serum calcium levels checked at least twice a week. Stop taking the drug if you see an increase in serum calcium and wait until this value returns to normal.
Dosage of Masak for each specific treatment purpose is as follows:
Osteoporosis: 1 tablet/time, 2 times/day. Increase dose to 2 tablets / time and take 2 times / day for 1 month if the previous dose is not effective. Rickets, osteomalacia, hypothyroidism: The initial dose is 1 tablet/time/day in the morning. After that, if the patient does not test positive and is clinically asymptomatic, the dose can be increased and used for 2-4 weeks. Bone dystrophy in people with kidney disease: The recommended initial dose of Masak is 1 tablet / time / day. Patients with slightly decreased or normal calcium levels take 1 tablet/ 2 days. After that, if the patient does not test positive and is clinically asymptomatic, the dose can be increased and used for 2-4 weeks. An overdose of Masak causes symptoms similar to those of a vitamin D overdose because Calcitriol is a metabolite of vitamin D. Or concomitant use of the drug with preparations containing calcium and phosphate can also cause symptoms of overdose. similar.
Manifestations of acute Masak overdose are headache, anorexia, constipation, nausea, and chronic disorders of the senses, dystrophy, accompanied by fever, dehydration, thirst, polyuria, infection urinary tract, emotionless. Chronic Calcitriol poisoning can cause secondary hypercalcemia, calcification of the renal cortex, lungs, myocardium and pancreas.
When an overdose of Masak drug, the patient should be induced vomiting or gastric lavage immediately to prevent the drug from being absorbed into the blood. Paraffin oil can be used to increase the fecal elimination of the drug. At the same time, the patient also needs to be checked for blood calcium levels many times, if it is still high, corticosteroids, phosphates or other appropriate diuretic measures can be used.

Masak medicine can cause some unwanted side effects with the frequency of occurrence as follows:
Common: Headache, fatigue, dizziness, weakness, somnolence; dry mouth, metallic taste, loss of appetite, nausea, vomiting, constipation, diarrhea, abdominal cramps; bone pain, myalgia, hypotonia, ataxia, tinnitus, excitability and rash. Uncommon: The drug Masak rarely causes side effects such as kidney dysfunction, kidney calcium infection, sexual impairment, itching, runny nose, itching, underdeveloped children, osteoporosis in adults, anemia, weight loss, pancreatitis, convulsions, photophobia, conjunctival and vascular calcifications. Rarely: Masak medicine rarely causes side effects such as arrhythmia, increased blood pressure; increased calcium, urine, urinary albumin, increased blood urea nitrogen, increased serum cholesterol, increased AST and ALT, decreased serum alkaline phosphatase levels, serum electrolyte disturbances, mild acidosis and psychosis God. If you see any strange symptoms after taking Masak, the patient should immediately report it to a doctor or go to a medical facility for a health check.

Do not use Masak in people with hypersensitivity to the ingredients of the drug, people with disorders related to increased serum calcium levels, people with manifestations of vitamin D toxicity. Pregnant women, children under 3 Age or pediatric patients undergoing hemodialysis should be cautious when using Masak because information on the safety of the drug in this group of subjects is limited. Breastfeeding women who take the drug must stop breastfeeding, the drug may be excreted in breast milk. Concomitant use of Masak with colestipol hydrochloride or cholestyramine may reduce the absorption of the drug in the intestine, therefore, these drugs should not be used together. Concomitant use of Masak with high doses of mineral oil may interfere with intestinal absorption of the drug. Therefore, it is necessary to reduce the dose or stop taking Masak. Concomitant administration of Masak with phenobarbital or phenytoin may decrease plasma concentrations of these two drugs and increase the metabolism of the Calcitriol component. Therefore, do not take these drugs together. Co-administration of Masak with corticosteroids may reduce the effect of Masak; with cardiac glycosides can cause arrhythmias. Above is all information about Masak medicine, patients need to carefully read the instructions for use, consult a doctor / pharmacist before using. Absolutely do not arbitrarily buy Masak medicine at home because there may be unwanted side effects.