Uses of medicine Kagawas 300


Kagawas 300 medicine has the main active ingredient is Nizatidine with a content of 300mg and other excipients in a sufficient amount. This is a medicine to treat diseases of the digestive tract, specifically treating stomach ulcers, gastroesophageal reflux disease.

1. What is Kagawas 300?


Kagawas 300 medicine has the main active ingredient is Nizatidine with a content of 300mg and other excipients in a sufficient amount. This is a medicine for the treatment of diseases of the gastrointestinal tract, namely the treatment of stomach ulcers, gastroesophageal reflux disease,...
Kagawas 300 is made in the form of hard capsules, suitable for use. by direct oral route. The box contains 3 blisters and each pack contains 10 pills.

2. What diseases does Kagawas 300 treat?


Kagawas 300 medicine has the main active ingredient Nizatidine, belongs to the group of drugs that inhibit gastric acid secretion, antihistamine H2, selected in the treatment:
Treatment of gastric ulcer - duodenal ulcer. Especially the drug for good use in cases of acute ulcers. Treatment of gastroesophageal reflux disease. Treatment of Zollinger - Ellison syndrome: is a syndrome caused by the appearance of one or more gastrin tumors in the digestive system that increase gastrin secretion. Thus, leading to an increase in gastric acid secretion. Treatment of symptoms of burning, heartburn, indigestion caused by excess gastric acid.

3. Usage and dosage of the drug Kagawas 300


3.1. Dosage of the drug Kagawas 300: Dosage for treatment of duodenal ulcer and progressive benign gastric ulcer: Take 300 mg once a day in the evening or 150 mg each time, 2 times a day in the morning and evening, in period from 4 to 8 weeks. The duration of treatment beyond 8 weeks has not been determined. Maintenance dose to prevent recurrent duodenal ulcer: 150 mg once daily in the evening. Treatment can last up to 1 year. Dosage for treatment of gastric and duodenal ulcers with Helicobacter pylori bacteria: Combination of Nizatidine (currently, a proton pump inhibitor is preferred for 1 week) with two of the antibiotics: Amoxicillin, Tetracycline, clarithromycin or antibiotics of the Imidazol group (Metronidazole). Dosage for treatment of gastroesophageal reflux disease: 150mg each time, 2 times a day for up to 12 weeks. You can take 300mg once at bedtime, but it is better to take it twice. Dosage to treat symptoms of dyspepsia: 75mg each time, can be repeated if necessary, up to 150mg/day, for a period of 14 days. Prophylaxis of symptoms of heartburn, indigestion, heartburn: Take 75mg 30-60 minutes before eating or drink once or twice a day (not more than 150mg/24 hours), use the drug during not more than 2 weeks. Dosage in the elderly: No dose adjustment is normally required for the elderly, except in cases of moderate to severe renal impairment with Clcr < 50 mL/min. Dosage in children: Currently, the safety and effectiveness of using nizatidine in children have not been established. 3.2. How to use Kagawas 300: Kagawas 300 is made in the form of hard capsules, suitable for direct oral use.

4. Undesirable effects of the drug Kagawas 300


In the process of using Kagawas 300, you may experience some unwanted effects, specifically as follows:
Anemia, skin urticaria, liver cell damage. For the central nervous system: transient mental confusion (rare). For endocrine system: Active ingredient Nizatidine has no anti-androgen effect. Impotence and decreased sex drive may also occur. Rare cases of gynecomastia in men. Hematology: Anemia was more common in patients with nizatidine-containing drugs than in patients with placebo. Fatal thrombocytopenia was observed in a patient receiving nizatidine in combination with another Histamine H2 antagonist; This patient also had a history of thrombocytopenia while being treated with other drugs. There have also been rare cases of thrombocytopenic purpura after taking drugs containing the active ingredient nizatidine. Skin: Sweating and urticaria are common in people using medicines containing Nizatidine. A number of other undesirable effects such as skin redness and exfoliative dermatitis have also been reported. Hypersensitivity Reactions: Specific rare hypersensitivity reactions such as bronchospasm, laryngeal edema, skin redness, increased eosinophil counts have also been reported. Other adverse reactions: Hyperuricemia/hyperuricemia not due to gout or nephrolithiasis, eosinophilia, fever and nausea have been associated with the use of drugs containing nizatidine as well. is recognized.

5. Interactions of drugs Kagawas 300


Because Kagawas 300 drug inhibits gastric acid secretion, gastric pH increases when using this drug. This reduces the absorption of some acidic drugs when used concurrently, specifically: Penicillin V, ketoconazole, itraconazole....
Because Antacid creates a protective film on the gastric mucosa - duodenum. will reduce the absorption of the drug Kagawas 300 . Therefore, if taking the drug with Antacid, it is necessary to take Kagawas 300 at least 2 hours before taking Antacid.

6. Some notes when using the drug Kagawas 300


6.1. Contraindications of the drug Kagawas 300: Do not use Kagawas 300 for people who are sensitive to any of its ingredients. If the user of Kagawas 300 has ever had a hypersensitivity reaction to any drug of the H2 antihistamine class, absolutely do not use this medicine. The reason is due to cross-sensitization between compounds belonging to the group of histamine antagonists with H2 receptors, including the active substance Nizatidine. Therefore, do not use the drug for people with a history of hypersensitivity to other substances that also antagonize histamine with H2 receptors. 6.2. Caution when using Kagawas 300: Caution should be taken when using Kagawas 300 for people with severe liver failure, because the drug is partially metabolized by the liver. Care should be taken when using Kagawas 300 in patients with renal failure because the drug is excreted by the kidneys in its active form. Caution when using Kagawas 300 for people with stomach cancer: Because when the stomach pH decreases, some bacteria can grow, creating nitrosamines from food, aggravating the cancer. You need to proactively inform your prescribing doctor if you are taking other medications. Limit drug interactions that adversely affect the patient's condition. If you are pregnant or breast-feeding or planning to become pregnant or suspect that you may be pregnant, consult your doctor before using this medicine. Do not use this medicine in people younger than 18 years old. Kagawas 300 medicine can cause some unwanted effects such as drowsiness, dizziness, headache, fatigue, so people who drive or operate machinery are advised to be careful when using the drug. 6.3. Notes on pregnancy and lactation For women during pregnancy: Caution should be exercised in pregnant women because Kagawas 300 can be transported across the placenta into the fetal circulation and harm the fetus. pediatric. Therefore, it is necessary to carefully weigh the benefits and harms for both mother and fetus before deciding to prescribe this object. For women in lactation: Women in lactation because the drug is excreted in breast milk. Therefore, the risks and benefits must be weighed in order to choose whether to discontinue Kagawas 300 or discontinue breast-feeding to ensure safety for both the mother and the nursing infant. Do not arbitrarily use this type of thuyoosc without carefully reading the instructions for use and instructions of the doctor to protect the mother and baby. In addition to treatment with Kagawas 300, people with peptic ulcer disease also need to avoid exposure to agents that can cause or aggravate symptoms or cause recurrence of the disease. include: Do not smoke (including passive smoking), do not drink alcohol, reduce psychological stress, do not arbitrarily use antipyretic, analgesic, non-steroidal anti-inflammatory drugs or NSAIDs.
Above is all information about Kagawas 300, patients need to carefully read the instructions for use, consult a doctor / pharmacist before using. Absolutely do not arbitrarily buy Kagawas 300 to treat diseases at home, because there may be unwanted side effects on health.

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