Uses of Metophage

Metophage drug with the main ingredient is Metformin hydrochloride 850mg, which is indicated for the treatment of diabetes patients. Here is some information about Metophage drug to help patients learn and use the drug safely and effectively.

1. What is Metophage?

Metophage is a drug belonging to the group of hormonal drugs. Metophage is prepared in the form of film-coated tablets, packaged in boxes of 3 blisters x 10 tablets.
Metophage drug has the main ingredient Metformin and some other excipients in the drug, just enough for 1 tablet.

2. What are the uses of Metophage?

Metophage 850 is indicated for the treatment of patients with diabetes. Components Metformin hydrochloride is a hypoglycemic biguanide used for the treatment of non-insulin dependent diabetes mellitus when glycemic control cannot be achieved with diet alone, but has no appreciable hypoglycemic effect in non-insulin dependent subjects. diabetes.
In obese patients, the drug can induce beneficial weight loss, sometimes this effect is the rationale for the combination of Metformin and Insulin in insulin-dependent diabetes.
As with many drugs, the specific mode of action of Metformin is unknown. There have been a number of theories explaining the mode of action, which are:
Inhibition of glucose absorption in the intestine. Increases glucose utilization in cells. Inhibits gluconeogenesis in the liver.

3. Dosage - how to take Metophage

3.1. How to use Metophage Metophage drug is manufactured in the form of film-coated tablets, which are tolerated in the body by mouth, according to tablets. Patients can use pure filtered water or cooled boiled water to take the medicine. Metophage should be taken after eating.
3.2. Dosage Dosage Metophage drug depends on each subject and the course of the disease will have the appropriate dose. The following is a reference dose of Metophage as follows:
Patients with non-insulin dependent diabetes: Using the drug at the starting dose should be 500mg of Metophage per day, it should be taken after meals to minimize the risk of complications. adverse drug effects on the gastrointestinal tract. In case, the patient's blood sugar is not controlled, the dose can be gradually increased to the maximum daily dose of 5 tablets of 500mg Metophage or 3 tablets of 850mg Metophage per day, divided into 2 to 3 times orally. during the day.

4. In which cases is Metophage not used?

Metophage drug is not used for patients with hypersensitivity or history of allergy to Metformin hydrochloride ingredients and excipients in the drug.
Do not use Metformin hydrochloride for patients with diseases such as: Kidney, liver, thyroid and respiratory failure.
Metformin should not be used in patients with dehydration, acute alcoholics, heart failure or any condition that could lead to lactic acidosis. Metformin is contraindicated in pregnant and lactating women.

5. Metophage drug interactions

Interactions between drugs can change the ability of the drug to work or increase the effects of side effects.
The only notable interaction is the interaction between the drug Metformin and alcohol: Drinking large amounts of alcohol during treatment with Metophage increases the risk of lactic acidosis.
In addition, patients need to remember to gradually increase the dose of Metophage as well as Sulfonylurea in patients receiving combination therapy to prevent possible hypoglycemic events.
Note: Before deciding to treat with Metophage, please tell your doctor or pharmacist about all prescription and non-prescription drugs, minerals & vitamins, herbal products other to be considered by the doctor and prescribe the drug with the appropriate dose.

6. What side effects does Metophage cause?

During the use of Metophage, patients may experience some unwanted side effects such as:
There is an increase in lactic acid causing acidosis. Gastrointestinal disorders such as nausea, abdominal pain, and diarrhea occur in about 10 to 15% of patients. Gastrointestinal disturbances can be significantly reduced if the patient takes Metformin after meals and gradually increases the dose. Long-term use of Metformin has been reported because the drug's effect on the absorption of Vitamin B12 in the small intestine can cause Vitamin B12 deficiency, but this side effect is very rare. In case of prolonged use of Metophage, it will cause some symptoms such as: Bitter mouth, loss of appetite, weight loss in patients.

7. What to do when using Metophage drug overdose?

If the patient uses an overdose of Metformin as directed by the doctor, it will lead to lactic acidosis.
Patients need to stop taking the drug and notify the doctor, take it to the nearest medical facility for timely treatment, to avoid unwanted harm.
The patient should be corrected for acidosis by intravenous injection of 7.5% sodium bicarbonate solution. In patients with severe acidosis, peritoneal dialysis or hemodialysis should be performed.

8. How to store Metophage

Patients need to store Metophage at room temperature, in the shade and avoid heat and moisture.
Metophage drug with the main ingredient is Metformin hydrochloride 850mg, which is indicated for the treatment of diabetes patients. To ensure the effectiveness of treatment and avoid unwanted side effects, patients need to strictly follow the instructions of the doctor, professional pharmacist.
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