Uses of Novadril

Novadril drug is made in the form of capsules with the main ingredient in each tablet is Cefadroxil 500mg. So what is Novadril and how is it used?

1. What is Novadril?

Novadril is an antibiotic drug, with the main ingredient being Cefadroxil, this is a first generation cephalosporin antibiotic. Cefadroxil has a medium antibacterial spectrum, effective against gram-positive bacteria such as staphylococcus aureus. , streptococcus and pneumococcus (except methicillin-resistant streptococcus). This active ingredient is also active against some gram-negative bacteria such as Klebsiella pneumoniae, E.coli, Proteus mirabilis and Shigella. The mechanism of action of Cefadroxil is to inhibit bacterial cell wall synthesis, the drug has a bactericidal effect, inhibits the final stage of bacterial cell wall synthesis, making bacteria no the protective wall will be destroyed.
Bacterial strains resistant to cefadroxil include: methicillin-resistant Staphylococcus, Proteus with positive indole reaction, Enterococcus, Enterobacter, Pseudomonas aeruginosa, Bacteroid.

2. Indications and contraindications of Novadril

Novadril drug is indicated in the following cases:
Urinary tract infections including: acute and chronic pyelonephritis, urethritis, cystitis. Respiratory tract infections including: pharyngitis, tonsillitis, bronchopneumonia and lobar pneumonia, lung abscess, acute and chronic bronchitis, pleurisy, empyema, laryngitis, inflammation middle ear. Skin and soft tissue infections include: Abscess, cellulitis, ulcers, lymphadenitis. Osteomyelitis, septic arthritis. Novadril is contraindicated in cases of hypersensitivity to Cephalosporin antibiotics.
Notes and precautions when using Novadril in the following cases:
The patient is allergic to penicillin antibiotics. Patients with renal failure Patients with gastrointestinal disease. Long-term use of Novadril may result in overgrowth of non-susceptible bacteria. The patient should be carefully monitored, if superinfection occurs, the drug should be discontinued and appropriate treatment instituted.

3. Dosage and how to use Novadril

Novadril is used orally. Dosage should follow the doctor's prescription, reference dose in specific cases as follows:
Adults: Use a dose of 500mg - 1g/time, 1-2 times a day, depending on the level of infection. bacteria. Children: Children 1-6 years old: Use a dose of 250mg / time, 2 times a day. Children over 6 years old: Use 500mg/time, 2 times daily. Dosage adjustment of Novadril is required in the elderly and in patients with renal impairment.

4. Novadril side effects

Most Novadril side effects are mild, including:
Nausea, vomiting Abdominal pain Diarrhea If you notice any unusual symptoms while using the drug, you need to tell your doctor right away. or go to a medical facility for timely treatment.

5. Interaction of Novadril with other drugs

Cholestyramine binds to Cefadroxil in Novadril in the intestine, slowing the absorption of the drug. When using Novadril together with Probenecid may reduce the excretion of Cefadroxil. Furocemide, aminoglycoside can synergistically increase the toxicity of Novadril on the kidneys.

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