Uses of Orolys

Orolys medicine is an antifungal medicine indicated for use in cases of gynecological infections. Orolys is available in the form of softgels. Once inserted into the vagina, the capsule dissolves to release the substance deep into the genital area. In the drug Orolys, there is a combination of antibiotics (neomycin, polymyxin B) with the antifungal drug nystatin, so the absorption through the mucosa of the drug is almost very little. Therefore, at therapeutic doses, the drug has very little absorption into the circulatory system, only having a local therapeutic effect.
Main ingredients of Orolys suppositories:
Neomycin: this is an antibiotic of the aminoglycoside group. This ingredient has a very good bactericidal effect by inhibiting the protein biosynthesis of bacteria. The drug works well with local infections of the eyes, skin and ears. Neomycin is best absorbed in the presence of mucosal lesions. Nystatin: An antifungal drug made from the fungus Streptomyces noursei. When nystatin is introduced into the body, the drug will bind to sterols at the cell membrane and change the permeability of the fungal cell membrane, inhibiting the growth of fungal spores. It is the best treatment for candida albicans and some other yeasts. Disadvantages: the drug has no effect on other types of bacteria. The drug is not absorbed through the mucous membranes and skin at topical doses. Polymyxin B sulfate: is a highly bactericidal active ingredient with the ability to change the structure and permeability of the cytoplasmic membrane of bacteria. Polymyxin B is poorly absorbed through the mucosa.

2.1. Orolys suppositories are indicated for use in the following cases:
Orolys suppositories are indicated for fungal infections of the genital area (cervical, vaginal) caused by bacteria or a mixture of fungi and bacteria. The drug is indicated for the treatment of infections caused by the fungus candida albicans. In addition, Orolys is also indicated for prophylactic use in cases such as before childbirth, before surgery on the genital area or after intrauterine exploration procedures.
2.2. Contraindications of using Orolys gynecological suppositories Contraindicated in cases of hypersensitivity to any component of the drug.
Pregnant and lactating women: There are many women who wonder if Orolys is good for pregnant women. In fact, up to now, there has not been a specific study that clearly demonstrates the safety or side effects of Orolys suppositories for pregnant or lactating women. As safety has not been established, it is still not recommended to use the drug during this time.

Orolys drug is a topical drug, used directly in the vagina, not an oral drug. Patients need to order 1 tablet daily for 12 consecutive days as prescribed by the doctor.
Best used in the evening before going to bed according to the following steps:
Clean the intimate area before placing the medicine. Note that you should use cleaning solutions with a suitable pH to avoid unbalanced vaginal pH, making the inflammation worse (can consult a specialist for advice on solutions). suitable hygiene).
Carrying out Orolys drug placement: The best position is to use the gynecological position, the person is lying on their back, with both legs bent at the knees. Place the tablet directly into the vagina, inserting as deep inside as possible. Note that can be placed directly with hands (need to ensure clean hands) or wear gloves. After placing the medicine, you should lie down for at least 15 minutes so that the tablet does not fall out.

If you miss a dose during treatment, take it again when you remember it that same evening. If you miss a dose too close to the time of the next dose, you should take the next dose as usual. Never take a double dose to make up for the missed dose. If you have an overdose, contact a specialist as soon as you see unusual symptoms in your body or go to the nearest medical facility for timely examination and treatment. The drug may lose its therapeutic effect if latex preparations or condoms are used during the injection. Birth control pills or spermicides can make them less effective or less effective. Orolys suppositories can be used during a normal menstrual period. Patients should use the drug exactly as prescribed by the doctor in terms of dosage and duration of use, because if enough amount is absorbed into the blood, Orolys gynecological suppositories can also cause systemic toxicity. Of particular note, hypersensitivity to topical antibiotics may affect current or systemic use in the future. Orolys is a topical medication commonly used to treat gynecological inflammatory problems, especially candida albicans infections. The drug is contraindicated in pregnant and lactating women. Therefore, consult your doctor before using the drug, especially in people with inflammation during pregnancy or breastfeeding.
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