Uses of Panactol 325mg

Panactol 325mg medicine has the main active ingredient Paracetamol. The drug works to relieve headaches, migraines, sore throats, menstrual cramps, body aches due to colds or flu....

Panactol 325mg medicine has the main ingredient is Paracetamol with the content of 325mg. This is a non-steroidal anti-inflammatory drug. Panactol 325mg is available in the form of a long tablet. Packing specification is box of 10 blisters, each blister contains 10 tablets.

Panactol 325mg drug has antipyretic effect, relieves pain for children in cases of colds, infections, viral infections, dengue fever, fever when teething or after vaccination... Paracetamol is an analgesic and anti-inflammatory drug. Antipyretic with good effect. Panactol 325mg drug acts on the thermoregulatory center in the hypothalamus causing hypothermia, increased heat loss due to vasodilation and increased peripheral blood flow, reducing body temperature in patients with fever. However, Panactol 325mg rarely lowers the normal body temperature. Paracetamol relieves pain by raising the pain threshold. At therapeutic doses, the analgesic and antipyretic effect of Panactol 325mg is equivalent to Aspirin, but Paracetamol has little impact on the cardiovascular and respiratory systems. Panactol 325mg does not change the acid - base balance, does not cause irritation, scratch or bleeding in the stomach. Paracetamol is rapidly and almost completely absorbed from the gastrointestinal tract. The mean half-life is 1.25 - 3 hours. The drug is metabolized mainly in the liver and is eliminated by the kidneys.

Panactol 325mg is prepared in the form of tablets, suitable for oral use.
Dosage: Take the medicine 4 to 6 hours apart if needed.
Adults: Take 1 capsule. Do not use more than 6 tablets / 24 hours. Children from 7 to 12 years old: Take 1⁄2 tablets of Panactol 325mg and do not take more than 3 tablets / 24 hours. The minimum interval between therapeutic doses is 4 hours. Note: Do not use Panactol 325mg for self-treatment for pain relief for more than 10 days in adults and for more than 5 days in children or for high fever (39.5 degrees Celsius) for more than 3 days unless directed by a doctor. In patients with severe renal impairment with creatinine clearance < 10 ml/min, the interval between oral doses should be at least 8 hours. Overdose cases and treatment:
Paracetamol overdose occurs when using a single toxic dose, repeated large doses of Paracetamol (7.5 - 10 g per day, for 1-2 days) or by taking the drug. long days. Therapeutic dose-dependent hepatic necrosis is the most serious acute toxic effect of overdose and can be fatal. Manifestations of Paracetamol overdose include signs such as nausea, vomiting, abdominal pain accompanied by cyanosis of the skin, mucous membranes and nails. Manifestations of severe poisoning with Paracetamol include initially mild excitement, agitation and delirium. This is followed by central nervous system depression such as stupor, hypothermia, fatigue, rapid and shallow breathing; arrhythmia, low blood pressure and circulatory failure. Treatment: Early diagnosis plays a very important role in the treatment of Paracetamol overdose. When intoxication with Paracetamol is severe, the user needs active supportive treatment. The treating doctor will prescribe gastric lavage in all cases, preferably within 4 hours after taking. Detoxification therapy is mainly the use of Sulfhydryl compounds. N - acetylcysteine ​​is effective when administered orally or intravenously. In addition, doctors may prescribe treatment with methionine, activated charcoal and/or salt bleach.

Uncommon side effects: Appearance of skin rash; nausea, vomiting; high toxicity to the kidneys when abused for a long time; neutropenia, pancytopenia, anemia. Rare adverse effects such as hypersensitivity reactions.

Long-term intake of high doses of Panactol 325mg slightly increases the anticoagulant effect of Coumarin and Indandion derivatives. Attention should be paid to the potential for severe hypothermia in patients receiving concomitant phenothiazines and antipyretic therapy. Anticonvulsants (Phenytoin, Barbiturates, Carbamazepine), Isoniazid and anti-tuberculosis drugs may increase the hepatotoxicity of Panactol 325mg. Excessive and long-term alcohol consumption can increase the risk of Paracetamol causing high toxicity to the liver.

Contraindications when using the drug:
People with sensitive or hypersensitivity to the drug and liver cell failure. People with a history of repeated anemia, with underlying medical conditions related to the heart, lungs, kidneys or liver. People with G6PD deficiency. Notes and precautions when using the drug:
For people with phenylketonuria - urine and people who have to limit the amount of phenylalanine put into the body, they should avoid using preparations containing Paracetamol with drugs or foods containing Aspartame. For some people with hypersensitivity, in particular, people with asthma should avoid the use of Paracetamol-containing preparations with drugs or foods containing sulfites. Panactol 325mg should be used with caution in people with a history of pre-existing anemia, impaired liver and kidney function. Drinking a lot of alcohol can increase the hepatotoxicity of Paracetamol, so avoid or limit alcohol when taking the drug. Physicians should warn users about signs of serious skin reactions during treatment with Panactol 325mg, such as toxic skin necrosis syndrome (TEN), Steven-Johnson syndrome (SJS) or Lyell syndrome. or acute generalized exanthematous pustulosis (AGEP). Use of drugs in pregnant and lactating women: Currently, the safety of Panactol 325mg for the fetus has not been established when used in pregnant women. Therefore, you should treat with this drug in pregnancy only when clearly needed. Use of drugs for machine operators: Panactol 325mg drug does not affect the ability to drive and use machines. In summary, Panactol 325mg has the effect of reducing headaches, migraines, sore throats, menstrual cramps, body aches due to colds or flu... To ensure safety for health and maximize effectiveness As a result of treatment, you need to take Merugold exactly as directed by your doctor.