Uses of Polisnale

Polisnale is a vaginal tablet used to treat conditions such as white discharge, abnormal vaginal discharge, vaginal itching,... Patients need to use the drug according to the doctor's instructions, avoid self-indulgence. treatment or change the dose to reduce the risk of adverse events.

Polisnale belongs to the group of gynecological drugs, prepared in the form of vaginal soft capsules and manufactured by Prime Pharm Co., Ltd. - Korea. Currently, Polisnale is recommended by doctors to reverse symptoms such as abnormal discharge, white discharge or vaginal itching caused by vaginal infections.
Polisnale is packaged in a box of 2 blisters x 6 tablets, each soft capsule contains the following main active ingredients:
Neomycin sulfate 35000UI. Nystatin content 100000UI. Polymyxin B sulfate content 35000UI. Other auxiliary excipients are enough for 1 tablet.

Each of the active ingredients in Polisnale will hold different roles and tasks, specifically:
Neomycin sulfate: Often used for topical treatment, has the ability to kill very well aerobic bacteria. In general, this active substance is relatively poorly bound to plasma proteins and the main site of diffusion is in the extracellular fluid. In fact, Neomycin sulfate is an antibiotic belonging to the Aminoside group, providing bactericidal effects through binding to the 30S subunit, thereby affecting the protein synthesis of bacteria. Nystatin: An active ingredient with effective antibacterial properties, especially Candida strains. This effect of Nystatin is due to sterol binding of the fungal cell membrane, which significantly alters the permeability of the membrane to the lethal ion. In general, Nystatin is well tolerated after introduction. On the other hand, this active ingredient is less toxic, so it is suitable for all ages. In addition, Nystatin has antifungal activity and is largely eliminated in the feces as unchanged drug. Polymyxin B sulfate: Is a polypeptide antibiotic, with antibacterial activity against some strains of Gram-negative aerobic bacteria, such as Klebsiella, Enterobacter, Salmonella, E.Coli, Bordetella, Pseudomonas aeruginosa or Pasteurella,. .. Active ingredient Polymyxin B sulfate is often very toxic to the kidneys, so it should only be used topically. The bactericidal ability of Polymyxin B sulfate is due to the association with Phospholipids, causing the bacterial plasma membrane to change structure as well as permeability.

Polisnale is used by doctor's prescription to treat the following cases:
Treatment of abnormal white blood and discharge. Treatment of vaginal itching. Prevents vaginal candidiasis. Treatment of vulvovaginitis. Treatment of nonspecific bacterial vaginosis. Helps in the treatment of vaginal bleeding.

Do not use Polisnale for the following cases without a doctor's prescription:
Patients who are hypersensitive or allergic to antibiotics of the Polypeptide, Aminoside group or any of the excipients in the drug formula . Polisnale is contraindicated for people who are using rubber devices such as diaphragms or preservatives in birth control devices. Polisnale is relatively contraindicated for people who are using spermicide because it can affect the effectiveness of vaginitis treatment.

Patients should visit a specialist directly to receive expert advice on the most appropriate dose of Polisnale for their health condition. The following is the dose of Polisnale that responds to the most common infections:
Usual dose: Vaginal 1 tablet / time / day in the evening, use continuously for 6 days. Dosage for chronic or serious infections: Vaginal 1 tablet/time, used 1-2 times/day and maintained for 6-12 days. The duration of using Polisnale will be determined specifically based on the severity - mildness of the disease condition as well as the patient's response. In addition, patients should absolutely avoid changing the dose and frequency of using Polisnale without the consent of the doctor.

Before using Polisnale, you need to carefully read the instructions in the leaflet attached to the product or place the medicine according to the following instructions:
Before inserting the medicine into the vagina, you need to clean the intimate area with salt water. dilute, then gently dry with a soft cloth. Lie on your back with knees bent and legs apart. Use 2 fingers to grip the tablet and place as deep inside the vagina as possible. After placing the medicine, you should close your legs and lie down for at least 15-20 minutes. You should wash your hands before as well as after inserting the medicine into the vagina to ensure hygiene. In addition, you should also trim your fingernails to avoid hurting the vagina.

During the use of Polisnale, patients may accidentally experience some unwanted side effects, such as:
Burning pain, irritation or itching in the intimate area. Allergic eczema reactions due to exposure or long-term treatment. This condition can spread to sites far from the treatment site. Drug hypersensitivity reactions, including urticaria or anaphylaxis. Causes adverse effects on kidney or hearing (rare). Abdominal cramps or dizziness. If the above side effects are mild, not very obvious or only transient, you do not necessarily need to stop taking the medicine. In order to avoid unwanted risks, you should proactively notify your doctor immediately if your body shows any unusual reactions. In case of need, your doctor will advise you to adjust the dose of Polisnale to suit your medical condition.

The treatment of gynecological inflammatory conditions with Polisnale will be safe and soon effective if the patient adheres to the following recommendations:
It is necessary to limit the time of using Polisnale vaginal tablets because risk of superinfection with drug-resistant bacteria and microorganisms. Systemic effects of Polisnale treatment cannot be ruled out, especially in patients with renal impairment. If you notice an allergic reaction or intolerance, you should stop using the drug. In the event of hypersensitivity to topical administration, the patient should consider whether treatment should be continued but in a different dosage form. Polisnale is not recommended for use in pregnant women because the ingredients in the tablet can cause adverse risks to the fetus, especially in the first 3 months of pregnancy. If you belong to this special group, please actively share with your doctor to make the right decision. The potential benefits and risks should be carefully weighed before using Polisnale in a nursing woman. The ingredients in Polisnale can reduce the strength of condoms and diaphragms. This causes the effectiveness of mechanical contraceptives to be significantly reduced. Ideally, you should avoid sex during treatment with Polisnale to prevent reinfection and unwanted pregnancy. People who are using spermicides should avoid using Polisnale. Carefully check the expiry date and quality of Polisnale suppositories before using. If the medicine has expired or shows signs of mold, watery,... you need to dispose of them immediately as directed. Tell your doctor about other medications you are taking at this time to prevent an adverse reaction.