Uses of Ramasav 40


Ramasav 40 is indicated in the treatment of gastrointestinal spasms, irritable bowel syndrome, biliary colic, biliary spasm, renal colic and urogenital spasm, uterine spasms. ,... Let's find out the necessary information about the use of Ramasav 40 through the article below.

1. What is Ramasav 40?


Active ingredient: Drotaverine
Class: Non-anticholinergic smooth muscle antispasmodic.
Brand name: Ramasav
Manufacturer: SaVi Pharmaceutical Joint Stock Company.
Ingredients:
Drotaverine hydrochloride: 40 mg Excipients: just enough

2. Uses of Ramasav 40


2.1 Indications Indications for treatment in the following cases:
Gastrointestinal smooth muscle spasm and irritable bowel syndrome. Biliary colic and biliary smooth muscle spasm: Cholelithiasis, cholecystitis, cholangitis. Renal colic and spasm of urogenital smooth muscle: kidney stones, ureteral stones, pyelonephritis, cystitis. Uterine contractions: Dysmenorrhea, threatened miscarriage, uterine contractions. 2.2 Dosage – How to use How to use:
The drug is taken orally.
Dosage:
Adults and children over 12 years old:
Usual dose: Take 3 - 6 tablets/day; 1-2 tablets each time.
Children:
Children aged 1 - 6 years: Ramasav tablets are not suitable for children 1-6 years old. Children 6 - 12 years old: Take 2 - 5 tablets / day; 1 pill each time. Patients with mild and moderate renal and hepatic impairment: Dosage adjustment of drotaverin may be necessary. However, data on these patients are still lacking, so when drotaverin is used, patients should be carefully monitored.
2.3 Overdose and management There are no data on drotaverin overdose.
If an overdose of drotaverin is taken, monitor the patient carefully, treat symptomatically and provide supportive treatment when necessary.

3. Note when using the drug Ramasav 40


Contraindications:
Hypersensitivity to Drotaverin and/or other components of the drug. Severe kidney or liver failure. Severe heart failure (decreased cardiac output). Children under 1 year old. Breastfeeding women. Note:
Use with caution in case of hypotension. Use with caution in patients with renal or hepatic impairment. Evaluative clinical studies in children have not been performed. Due to the presence of lactose in the preparation, patients with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption should not take this medicine. Effects of the drug on people driving and operating machines:
Due to the effects of dizziness, hypotension, headache can occur although rare; Caution should be exercised when driving or operating machinery after taking the drug.
Use in pregnancy and lactation:
Warning rating
AU TGA pregnancy category: NA
US FDA pregnancy category: NA
Pregnancy:
Animal studies have shown that the drug does not teratogenic. However, as with most drugs, prolonged use should be avoided with caution during pregnancy or lactation.
Lactation:
Animal studies have shown that the drug is not teratogenic. However, as with most drugs, prolonged use should be avoided with caution during pregnancy or lactation.

4. Side effects of the drug Ramasav 40


Rare (≥ 0.01% and <0.1%): Palpitations, hypotension, headache, dizziness, insomnia, nausea, constipation, allergic reactions (angioedema, urticaria , rash, itching).
Inform the doctor about the unwanted effects encountered when using the drug.
Instructions on how to manage ADR:
Stop using the drug. With mild adverse reactions, usually only discontinuation of the drug is necessary. In case of severe hypersensitivity or allergic reaction, it is necessary to conduct supportive treatment (keep breathing and use epinephrine, breathe oxygen, use antihistamines, corticosteroids...).

5. Drug interactions


Levodopa: Reduces the anti-Parkinsonian effects of levodopa. Papaverin, other antispasmodics and bendazol: Increased antispasmodic effect. Morphine: Reduces the effect of morphine.

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