Uses of Rmekol Extra

Rmekol Extra is a multi-component tablet used to treat colds and flu symptoms, relieve pain, and reduce fever effectively. To help you better understand the uses of Rmekol extra, as well as ensure the effectiveness of using Rmekol extra, users need to follow the doctor's instructions, and refer to the information content in the article about the product. Use the following drug Rmekol extra.

1. What are the uses of Rmekol Extra?

1.1. What is Rmekol Extra?

Rmekol extra is an antiallergic drug and is used in cases of hypersensitivity. Drugs manufactured by Sao Kim Pharmaceutical Joint Stock Company circulated in Vietnam and are registered with VDK VD-28013-17. Rmekol extra ingredients Paracetamol 500mg; Loratadine 5mg; Dextromethorphan HBr 15mg. The drug has a dosage form: Film-coated tablets.

1.2. What are the uses of Rmekol Extra?

The drug works in the following cases:
Pain relief and fever reduction in colds, body aches, coughs, runny noses, chills. Treatment of flu symptoms: Fever, cough, headache, muscle aches, joints, stuffy nose, runny nose, watery eyes, itchy eyes, sinusitis, seasonal runny nose, rash, rhinitis allergy .

2. How to use the drug Rmekol extra

2.1. How to take Rmekol Extra?

Use orally.

2.2. Dosage of the drug Rmekol extra

Adults and children over 12: Take 1 capsule/time, 2 times a day. Children 6-12 years old: take 1/2 tablet/time, 2 times a day. It is necessary to apply the exact dose of Rmekol extra indicated on the package, the drug leaflet or the instructions of the doctor or pharmacist. Do not arbitrarily calculate, apply or change the dose. Dealing with missed doses:
Usually drugs can be taken within 1-2 hours compared to prescribed in the prescription. Unless there is a strict rule about the time of use, the medicine can be taken a few hours after forgetting. However, if the time is too far from the time you need to drink, you should not take it, which can be dangerous for the body. It is necessary to strictly adhere to or consult a doctor before making a decision. Overdose treatment:
Unusual symptoms of overdose should be reported to the doctor or medical person in charge. In case of an overdose of Rmekol extra, there are symptoms that require emergency: Call 911 immediately for guidance and help. Family members should bring medical records, all prescriptions / bottles of medicine that have been and are being used so that doctors can quickly diagnose and treat.

3. Contraindications of the drug Rmekol extra

Children under 12 years old. Hypersensitivity to drug components. Not for use by pregnant and lactating women.

4. Notes when using Rmekol extra

4.1. Use on pregnant women and lactating mothers

Pregnancy: Paracetamol and Loratadine have no adverse effects on the fetus at the recommended doses for pregnant women. There are no data on the use of Dextromethorphan in pregnant women. Use with caution during pregnancy, use only when clearly needed. Lactation: Paracetamol, Loratadine are excreted in breast milk but are of no clinical significance. There are no data on whether Dextromethorphan and its metabolites are excreted in human milk. Therefore, it should not be used by women who are breastfeeding.

4.2. Drivers and machine operators

Side effects: dizziness, drowsiness affect the ability to drive and use machines. Be careful in this case.

4.3. Another special note

Paracetamol:
Should not be combined with other drugs containing Paracetamol to avoid overdose or drug poisoning. When symptoms persist for more than 5 days or fever persists for more than 3 days, consult a doctor. With caution in liver and kidney disease, in cirrhotic patients there is a higher risk of overdose. Warning some serious but rare skin reactions Steven-Johnson syndrome, toxic skin necrosis, Lyell's syndrome, acute generalized exanthematous pustulosis. Loratadine:
Liver failure. Discontinue use 48 hours before performing skin tests for allergies because it may interfere with the results of positive test reactions. Dextromethorphan hydrobromide, with caution in the following people:
Cough with excessive phlegm, chronic cough in smokers, asthma or emphysema. At risk or experiencing respiratory failure. Are taking drugs that inhibit the enzyme CYP2D6.

5. Side effects of the drug Rmekol extra

Fatigue, headache, dizziness, urinary retention, dry mouth, digestive disorders, gastritis, constipation, pancreatitis, hematological changes.

6. Drug interactions

Some interactions that have been reported include:
Paracetamol: Metoclopramide and Domperidone: Accelerates the absorption of Paracetamol. Cholestyramine: Decreased absorption of Paracetamol. Anticoagulants: Increased effectiveness with long-term use of Paracetamol because of the increased risk of bleeding. However, at usual doses the effect is not significant. Loratadine: Inhibitors of CYP3P4, CYP2D6: Increased concentrations of Loratadine, thereby increasing side effects. Ketoconazole, Erythromycin, Cimetidine: Increases plasma concentrations of Loratadine. Dextromethorphan HBr: Alcohol: Increases the sedative effect of this drug. MAOs, antidepressants, SSRIs: Risk of Serotonin syndrome resulting in altered mental status, tremors, tremors, increased blood pressure, myoclonic tremor, hyperreflexia, restlessness, sweat. CYP2D6 inhibitors such as Fluoxetin, Methadon, Paroxetin, Quinidine,... increase the concentration of Dextromethorphan, increasing the unwanted effects of the drug (such as insomnia, agitation, tremor, diarrhea, confusion, respiratory failure) and develop Serotonin syndrome. Quinidine: Increased dextromethorphan plasma concentrations up to 20-fold increases the CNS disturbance side effects of this drug. To ensure safety and effectiveness, tell your doctor about all medications, health foods you are taking, and other illnesses you have.

7. How to store Rmekol extra

Store the medicine below 40 degrees Celsius, preferably 15-30 degrees Celsius, avoid freezing the solution or suspension.

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