Uses of Sunbakant

Each Sunbakant tablet contains 10mg of Rosuvastatin as Rosuvastatin calcium as the main ingredient. Rosuvastatin is a selective and competitive inhibitor of HMG-CoA reductase, which catalyzes the conversion of 3-hydroxy-3-methylglutaryl coenzyme A to mevalonate, a cholesterol precursor. The main site of action of rosuvastatin is the liver, the target organ of cholesterol lowering.
Rosuvastatin increases the number of LDL receptors on the surface of cells in the liver, thereby increasing the absorption and catabolism of LDL, and inhibits the synthesis of VLDL in the liver, thereby reducing the components. LDL and VLDL.
Indications: Use Sunbakant in the following cases:
Treatment of hyperlipidemia, including: Primary hypercholesterolemia (type IIa), hypertriglyceridemia (type IV) and mixed disorders (type IIb); Treatment of hypercholesterolemia in homozygous familial. Contraindications : Do not use Sunbakant in the following cases:
People with hypersensitivity to any of the ingredients in Sunbakant; Patients with advanced liver disease including elevations in serum transaminases more than 3 times the upper limit of normal and unexplained persistent elevations in serum transaminases; Patients with severe renal failure (ClCr < 30ml/min); People with muscle diseases; Pregnant and lactating women, women of childbearing potential but not using appropriate contraceptive methods; People who are using cyclosporin.

How to use : Take Sunbakant orally in a single dose at any time of the day, with or without food.
Dosage:
Maintain diet: Use starting dose 5 - 10mg/time/day, increase dose every 4 weeks if needed and maximum 20mg/time/day; People with severe high blood cholesterol: Use a dose of 40mg/time/day; Elderly patients, patients at risk of myopathy, Asian patients: Initial dose of 5mg; Patients using cyclosporin: Use a maximum dose of 5mg/time/day; Patients using gemfibrozil or ritonavir - boosted lopinavir: Use a maximum dose of 10mg/time/day; People with marked hypercholesterolemia such as patients with homozygous familial hypercholesterolemia: Use a dose of 20mg/time/day; People with renal failure (ClCr 30 - 60ml/min): Use dose 5mg/time/day, maximum use 20mg/time/day; Using combination atazanavir, atazanavir/ritonavir and lopinavir/ritonavir: Maximum dose 10mg/time/day. Overdose: If you take an overdose of Sunbakant or have unusual symptoms, the patient should notify the doctor and be hospitalized immediately to avoid the risk of dangerous complications.
Missed dose: In case of missing dose of Sunbakant, the patient absolutely should not take a double dose on the next use because this can be dangerous. Patients should contact a specialist for advice on missed doses of Sunbakant and appropriate adjustment.

During the use of Sunbakant, patients may experience some undesirable effects such as:
Diabetes, increased HbA1c, increased blood sugar; Dizziness, headache, muscle pain, constipation, abdominal pain, nausea; Cognitive decline, weakness. When experiencing side effects of the drug Sunbakant, the patient should notify the doctor about the symptoms encountered for timely advice and treatment.

Some things patients need to keep in mind before and while using Sunbakant are:
Caution when using Sunbakant for patients: Hypothyroidism, impaired kidney function, personal or family history of disorders hereditary muscular dystrophy; history of liver disease or heavy alcohol consumption, history of myotoxicity from previous fibrate/statin use, patients 70 years of age or older with risk factors for rhabdomyolysis (conditions that cause elevated drug levels in the blood, concomitant use with fibrates); If serum creatine kinase is significantly elevated, myopathy is diagnosed or suspected, Sunbakant should be discontinued; Patients should reduce the dose of Sunbakant when using a dose of 40mg/day and have prolonged proteinuria without an obvious cause; Use caution when using Sunbakant in patients with total lactase deficiency, galactose intolerance or glucose - galactose malabsorption; Drivers and machine operators when using Sunbakant should be cautious; Discontinue Sunbakant if the patient has a CK > 5 x ULN or severe muscle symptoms; Sunbakant should not be used in patients with sepsis, hypotension, trauma, major surgery, endocrinology, electrolyte disorders, severe metabolism such as uncontrolled convulsions; In order to avoid Sunbakant drug interactions, patients should inform their doctor about the drugs they are currently or recently using, so that the doctor can consider and adjust accordingly. In the process of using Sunbakant, patients and family members need to pay attention to the instructions and strictly follow the doctor's instructions. At the same time, the patient must not arbitrarily stop taking the drug, change the time of use or dose of the drug, ... This is to bring the best effect during the treatment process, minimizing the risks of occurrence. unpredictable incidents.
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