Uses of Suppains

Suppains is a pain reliever and antipyretic drug containing the main ingredient Aceclofenac 100mg, along with other pharmaceutical substances and excipients. The drug is used in painful inflammatory arthritis. So what is Suppains and how does it work?

The main ingredient of Suppains is Aceclofenac. The drug is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory and analgesic effects. The pharmacological mechanism shows that aceclofenac effectively inhibits the enzyme cyclooxygenase, thereby inhibiting the synthesis of prostaglandins - chemical mediators of inflammation and pain.
After oral administration, aceclofenac is well absorbed in the intestinal tract, the highest drug concentration in the blood after oral administration is from 1.25 to 3 hours. The percentage of drug bound to protein is over 99%, after 2 to 3 hours, the drug concentration is reduced by half in the blood. The drug is widely distributed into the joint tissues, and two thirds of the drug is excreted by the kidneys in the urine as metabolites. According to the study, there was no difference in the pharmacokinetics of Suppains in adults and the elderly.

Indications for use of Suppains for anti-inflammatory and pain relief in cases of arthritis after
Rheumatoid arthritis. Inflammation in the vertebrae causes stiffness and pain in the joints. Other cases of chronic arthritis. Do not use Suppains in the following cases:
Patients who are allergic to aceclofenac, ibuprofen, aspirin, other NSAID anti-inflammatory drugs and excipients contained in the drug. Children under 15 years of age are not indicated for the use of drugs. Have a history or history of diseases causing ulcers, gastrointestinal bleeding. Patients with severely impaired liver and heart function. Patients with moderate to severe renal function.

3.1. How to take Suppains are taken orally, during or after meals. Patients should take the drug with a little water just enough, do not chew or crush the tablet.
3.2. Dosage Usual dose: 02 tablets divided into 2 times, 1 tablet each time, divided into 2 times (morning and evening). Patients with liver and kidney failure: The starting dose of treatment is 01 tablet/time/day. Signs of overdose appear mild such as nausea, headache, vomiting, somnolence, dizziness ... At that time, it is necessary to stop the drug and the patient needs help, medical intervention such as taking activated charcoal, Gastric lavage is effective if an overdose is taken within 1 hour.

The harmful side effects when taking the drug can be encountered on the organ systems, manifest in clinical at different levels such as:
Digestive system: Common as signs of disorders (dyspepsia, functional dyspepsia, etc.) vomiting, nausea, diarrhea), can cause severe bleeding, ulceration, gastrointestinal bleeding. Central nervous system: Headache, dizziness, dizziness, restlessness, tinnitus, neurasthenia, sleep disorders such as insomnia. Systemic: Rash, angioedema, fever, hypersensitivity reactions, vasculitis due to leukocyte deposition, hemoptysis. Hematology: may change hematological indicators such as thrombocytopenia, neutropenia, agranulocytosis, anemia, eosinophilia. Other signs: Pancreatitis, alveolitis, Stevens-Johnson syndrome (SJS), eosinophilic lung disease, alveolitis, malignant epidermal necrolysis.

Inform your doctor about all the medicines you are taking, because there are some groups of drugs that can interact to affect the quality of taking them such as: Lithium, Digoxin, diuretics, anticoagulants such as warfarin, Methotrexate , Quinolone, antidiabetic drugs.... Do not overdose or take together with anti-inflammatory pain relievers of the same group or with corticosteroids for the purpose of shortening the duration and reducing pain. For the elderly, the dose of the drug does not change. However, it is necessary to monitor the oral process to prevent adverse complications occurring in the gastrointestinal tract such as: vomiting blood, black stools, stomach bleeding. Patients with severe liver failure, heart failure, hypertension must be monitored during drug administration. Because the drug can reduce fertility, the drug is not used for women who want to become pregnant, are interfering with infertility problems, and women who have difficulty getting pregnant. Be careful in using Suppains in patients with a history of asthma, as the side effect causes airway constriction in many patients. Avoid using the drug on women during pregnancy, mothers who are breastfeeding. Patients with dizziness, headache or central nervous system disorders while using the drug should stop directly driving, operating machinery and equipment. Hopefully, with the above information, you already know what Suppains is and how it works. Patients only use the drug when prescribed by the doctor's prescription. If you have any questions, please immediately contact your doctor, pharmacist or specialist for the most accurate examination, advice and opinion.