Uses of Sutra

Sutra medicine has the main ingredient is Sucralfate and the same excipients are just enough. Prepared in the form of an oral suspension.
Sucralfate is a salt complex of Aluminum Hydroxyd and Sucrose Octasulfate. It dissociates in the acidic environment of the stomach into an anionic form, which binds to the base of the ulcer. This binding helps create a barrier to protect the stomach lining from the attack of factors such as Pepsin, bile salts or gastric acid. Sucralfate also increases the secretion of gastric mucus.
Sucralfate is also an acid buffer and inhibits the action of Pepsin, which contributes to the absorption of bile salts. These properties of sucralfate enable the drug to act as a barrier against attack by acids, pepsin, and bile salts.
Sucralfate can also bind to intact mucosa. Helps create a barrier to protect the healthy mucosa from attacking factors. In addition, Sucralfate increases the levels of fibroblast growth factors and epidermal growth factors which help to rapidly heal the gastrointestinal mucosa.

Sutra medicine is indicated in the following cases:
Treatment and prevention of recurrence of diseases such as acute and chronic gastric and duodenal ulcers, ulcers caused by benign causes, gastroesophageal reflux disease, ... Prevention of ulcer recurrence due to stress. Prophylaxis of peptic ulcers caused by the use of drugs that damage the gastrointestinal tract such as non-steroidal anti-inflammatory drugs (NSAIDs). Do not use Sutra for patients who are sensitive to any of the ingredients of the drug. Children under 18 years of age are not recommended to take Sutra.

3.1 Sutra dosage 1g For duodenal ulcer, use 2 packets of Sutra/time and 2 times/day, in the morning and before going to bed at night, use continuously for 4 - 8 weeks. For the prevention of duodenal ulcer recurrence, the dose should be reduced to 1 sachet of Sutra twice a day for no more than 24 weeks. Benign stomach ulcers are used at a dose of 1 sachet of Sutra x 4 times/day, used until the patient is completely cured of the ulcer. Patients with gastroesophageal reflux disease: Should take 1 packet of Sutra / time and 4 times / day, at the time before eating and going to bed at night for 1 hour. If the patient is infected with Helicobacter pylori , it is necessary to combine the use of antibiotics or other suitable HP drugs in addition to treatment with Sutra . 3.2 How to use Sutra Sutra is prepared in the form of an oral suspension, not for injection only. Mix Sutra with a little boiled water to cool, stir well to mix together and must be used immediately after mixing. Do not take Sutra with food but should be taken on an empty stomach, preferably 1 hour before or 2 hours after a meal.

Common is constipation when taking Sutra. In addition, the drug may also experience some other side effects such as diarrhea, bloating, indigestion, dizziness, trouble sleeping, insomnia, headache, back pain, erythema,... Unexpected effects More rarely, it causes shortness of breath, Quincke's edema, laryngospasm or a feeling of a foreign body in the stomach, ...

Sutra has Phosphate binding property. A decrease in blood phosphate may occur in some patients taking Sutra, even those without renal impairment. Treatment with Sutra should be used with caution in patients with pre-existing hypophosphataemia and, if used, should be monitored regularly for phosphate levels. Patients with chronic renal failure or those on dialysis often have impaired excretion of aluminum compounds. In addition, aluminum also does not pass through the dialysis membrane because it binds to plasma proteins such as Albumin and Transferrin. May lead to aluminum accumulation. The problem of aluminum accumulation and aluminum toxicity can cause osteodystrophy, osteopathy, and encephalopathy in patients with renal failure. Therefore, Sutra must be used with caution in patients with chronic renal failure. The risk of aluminum toxicity may also be increased if Sutra is taken with Vitamin D or with vitamin D analogues such as paricalcitol. When treating Sutra drugs should only be used short-term and should prevent the risk of recurrence by changing diet and living. There have been no reports of adverse effects in pregnant women. Check with your doctor before taking this medicine to make sure it's safe for your unborn baby. Breastfeeding mothers can be used Sutra medicine. Drug Interactions: Combination of antacids with Sutra may be indicated to relieve pain symptoms caused by ulcers, but the concomitant use of these drugs makes it difficult for Sutra to bind to the gastrointestinal mucosa. , has a great influence on the effectiveness of treatment, so antacids should be used at least half an hour before taking Sutra; Sutra reduces the absorption of drugs such as Theophyllin, Warfarin, Phenytoin, Digoxin, Ranitidine, Ciprofloxacin,... Sutra should be stored at a temperature of 25 - 30 degrees Celsius, in a cool place, away from light. light, moisture. Do not let children come into direct contact with the Sutra. Above is the information about the uses, dosage and usage of Sutra, if you have any questions, you should consult your doctor or pharmacist before using.