Uses of Tiecarbin Powder For I.V. Injection

Tiecarbin Powder is a prescription drug used in the treatment of many different infectious diseases such as respiratory tract infections, gynecological infections,... So what is the use of Tiecarbin Powder and how to use it? How to use this medicine?

Tiecarbin Powder is an antibiotic, made in the form of a powder for injection, with the main ingredients in each powdered vial including:
Imipenem (as Imipenem monohydrate) 500mg; Cilastatin (as Cilastatin sodium) 500mg Imipenem is a very broad spectrum antibiotic of the beta-lactam group. Imipenem has a rapid bactericidal action because it interacts with several penicillin-binding proteins (PBPs) located on the outer membrane of bacteria. Thereby, inhibiting the synthesis of bacterial cell wall by the same mechanism as other beta-lactam antibiotics.
Imipenem is often combined with Cilastatin for the treatment of serious hospital-acquired infections caused by gram-negative and gram-positive aerobic and anaerobic bacteria (not indicated for central nervous system infections). diseases), infections caused by drug-resistant Pseudomonas and Acinetobacter species.
Tiecarbin Powder is indicated in the following cases:
Abdominal infections Lower respiratory tract infections Gynecological infections Genitourinary tract infections Bone and joint infections Skin and soft tissue infections. Endocarditis Sepsis. Tiecarbin Powder is contraindicated in cases where people are hypersensitive to the drug.
Notes and precautions when using Tiecarbin Powder:
Partial cross-allergy with other beta-lactam antibiotics. People with a history of digestive disorders. If there are CNS symptoms, it is necessary to reduce the dose or stop taking Tiecarbin Powder. Use with caution in pregnant and lactating women. Children < 3 months.

Tiecarbin Powder is used by injection. Preparation and use should follow the manufacturer's instructions. Solution for intramuscular injection is not intended for intravenous use. Solution for intravenous infusion should not be used for intramuscular injection.
Dosage is calculated according to the imipenem in the compound. Dosage of Tiecarbin Powder should be according to the doctor's prescription, the reference dose for specific cases is as follows:
Infections caused by susceptible bacteria in adults, using intravenous infusion, dose 1 - 2 g/day (divided into 3-4 times). In infections caused by desensitized bacteria in adults, doses up to 50 mg/kg/day, up to a maximum of 4 g/day, can be used. Children over 3 months old: Use a dose of 60mg/kg/day, the maximum dose is 2g/day, divided into 4 times. Children weighing over 40kg use the drug according to the adult dose. Infection prevention in adults: Administer 1000 mg intravenously at the start of anesthesia and 1000 mg 3 hours later. Renal impairment: Use a maximum dose of 2g/day.

During the use of Tiecarbin Powder, you may encounter some side effects of the drug, including:
Thrombophlebitis Pain, stiffness, erythema and tenderness at the injection site. Nausea, Vomiting Diarrhea Fever Fever Lowering Blood Pressure Convulsions Dizziness Itching Urticaria Drowsiness Oral candidiasis Tachycardia Oliguria/anuria If you notice any unusual symptoms during use When using Tiecarbin Powder, you need to immediately notify your doctor or go to a medical facility for timely support.

Tiecarbin Powder may interact when used together with Ganciclovir medicine.