Uses of Tiphacipro 500


Tiphacipro 500 is a drug in the group of drugs to treat parasites, anti-infectives, antivirals and antifungals. Tipharipro 500 is manufactured by Tipharco Pharmaceutical Joint Stock Company with the main ingredient being Ciprofloxacin 500mg. For more detailed information about Tiphacipro 500, readers can refer to the article below:

1. What is Tiphacipro 500?


Tiphacipro 500 medicine has the main ingredient Ciprofloxacin 500mg (in the form of Ciprofloxacin hydrochloride 582mg) and other active ingredients and excipients. The drug is prepared in the form of film-coated tablets, packed in a Box of 2 blisters x 10 tablets; Box of 10 blisters x 10 tablets.
Tiphacipro medicine contains Ciprofloxacin which is an active ingredient of the quinolone group with broad bactericidal spectrum and strong activity; This substance has the effect of inhibiting the bacterial gyrase enzyme, thereby making the bacteria reduce their ability to reproduce quickly.
This drug is not concurrently resistant to other antibiotics not in the gyrase inhibitor class. Therefore, Tiphacipro drug is highly effective against bacteria that are resistant to other antibiotics such as aminoglycosides, tetracyclines, penicillins, cephalosporins and other antibiotics.
Tiphacipro is easily and rapidly absorbed from the gastrointestinal tract. When used concurrently with food and antacids, the absorption of Tiphacipro drug is slowed but this does not significantly affect the drug's effects. The bioavailability of Tiphacipro is about 70-80%.
Tiphacipro drug, after being taken into the body, the time for the drug to reach the maximum concentration in the blood is 60 -90 minutes. Tiphacipro is present in sites of infection with high concentrations of the drug, such as in body tissues and fluids.
The time that the drug Tiphacipro has half its concentration in the blood is almost 4 hours (3-5 hours), so you only need to use the drug twice a day in the morning and evening. After entering the body, this drug is metabolized by the liver.
After intravenous infusion, 2⁄3 doses of Tiphacipro used will be excreted in the urine through glomerular filtration and tubular secretion; Approximately 14% is excreted in the feces. Most of the active substance will be excreted within the first day of taking the drug.

2. What are the effects of Tiphacipro 500?


Tiphacipro is used in the following cases:
Complicated and uncomplicated infections caused by pathogens sensitive to ciprofloxacin include:
Respiratory tract infections such as pneumonia, bronchitis . Infections of the skin and soft tissues; bones and joints such as boils, abs. Otitis media, sinusitis Infections of the genital organs, including gonorrhea, adnexitis, prostatitis. Infection of the eye, kidney or urinary tract infection. Intra-abdominal infections (eg, gastrointestinal or biliary tract infections, peritonitis). Sepsis . Infection or risk of infection (prophylaxis) in immunocompromised patients (eg, immunocompromised or neutropenic patients). Indicated for selective intestinal decontamination in immunocompromised patients (oral tiphacipro).

3. Contraindications of Tiphacipro 500


Do not use Tiphacipro in case of hypersensitivity to the components contained in this medicine or the quinolone group. The drug Tiphacipro should not be used in pregnant and lactating women; children and adolescents, because no safety studies have been performed in these subjects and because animal studies have concluded that the potential for cartilage damage in underdeveloped subjects. Do not use this medicine if you have ever had a tendon rupture and tendinitis because Tiphacipro medicine can make it worse.

4. Dosage - how to use Tiphacipro 500


How to use: Tiphacipro 500 is prepared in the form of film-coated tablets, you should take the drug with a full glass of water, food, although it does not affect absorption, the manufacturer still recommends that you use it. Take the medicine about 1 hour away from meals.
Dosage:
Tiphacipro is used as prescribed by a doctor, you can also refer to the following recommended dose:
Dosage for adults with mild and moderate infections: Tiphacipro 250mg - 500mg, taken 2 times / day. In case of severe infection, with complications, adults should take the dose of Tiphacipro 750mg, taken twice a day. The duration of use of the drug usually lasts 5-10 days. For renal failure, the dose is adjusted and the time between 2 doses is adjusted based on the patient's glomerular filtration rate. Avoid self-administering this medication without consulting your doctor. Patients with impaired liver function do not need to adjust the dose of Tiphacipro

5. Undesirable effects when using Tiphacipro 500


While using Tiphacipro you may experience some unwanted effects that may occur such as
Occasionally you may experience symptoms of digestive disorders such as abdominal pain, abdominal distention, vomiting, belching, confusion dyspepsia, loss of appetite, diarrhea. Headache. Laboratory abnormalities such as increased BUN, increased liver enzymes, increased blood creatinine. Rare symptoms such as myalgia, arthralgia, pseudomembranous colitis, stomatitis. Shock, photosensitivity, erythema, edema, acute renal failure, jaundice, hematologic changes are rare. The undesirable effects mentioned above have not been fully listed, so if you detect any abnormal signs, you should immediately notify your doctor for advice and timely treatment.

6. Notes when using Tiphacipro 500


Inform your doctor about your history of allergies, medications you are taking, medical history and current diseases so that the doctor can advise and make the right choice, avoiding the effects Undesirable and possible drug interactions during treatment may occur. Drugs known to interact with Tiphacipro include antacids, Theophylline, NSAIDs, cyclosporine sucrafate, metal ions. This drug should be used with caution in the elderly, patients with severe renal impairment, hemodynamic disturbances in the brain. In case you experience pain, tendonitis or tendon rupture while using the drug, you should immediately stop taking Tiphacipro and inform your doctor so that he or she can offer an alternative or appropriate treatment for you. Use this drug with caution in patients with epilepsy or central nervous system damage such as seizures, strokes; Consider using this drug after the benefits outweigh the risks because of its undesirable CNS effects. Do not use the drug for women who are breastfeeding and pregnant women because there are not enough studies on the effects of the drug on these subjects. Do not use the drug when you are operating equipment and driving because the drug has undesirable effects on the central nervous system such as headache, dizziness. In summary, Tiphacipro is a broad-spectrum bactericidal antibiotic, used in the treatment of infections, although the use of the drug has been specified by the manufacturer, but to avoid drug resistance in patients, you should consult Consult your doctor before taking the medicine.
Above is information about the drug Tiphacipro, in case readers have any questions that need to be answered, please contact your doctor / pharmacist to get an accurate and quick answer.

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