Uses of Todexe

Todexe belongs to the group of drugs for the treatment of eye, ear, nose and throat diseases with ingredients Tobramycin and Dexamethasone. So what is the use of Todexe and how should it be used to get the best effect?

Todexe drug, a group of drugs used to treat diseases of the eyes, ears, nose and throat, contains Tobramycin in the form of Tobramycin sulfate with the content of 15mg/5ml and Dexamethasone phosphate with the content of 5mg/5ml. The drug is prepared in the form of a solution for direct eye drops. Packing is a medicine box containing 1 vial of 5ml
Todexe drug is a combination of antibiotics and multi-dose steroids to fight local infections of the eyes. Tobramycin is an antibiotic that inhibits protein synthesis in susceptible bacteria by irreversibly binding to the 30S ribosomal subunit. The active ingredient Dexamethasone sodium phosphate has the main use of anti-inflammatory, anti-allergic and immunosuppressive to reduce swelling, inflammation and edema caused by inflammatory agents. Active ingredient Tobramycin: The pharmacokinetic properties of the eye drops have not yet been found. Active ingredient Dexamethasone: when used topically, it can penetrate into the synovial, conjunctiva, and through the skin. This active substance is metabolized in the liver, excreted by the kidneys.

Topical treatment of inflammatory ocular conditions that have responded to steroids and where corticosteroids are indicated in the presence of superficial bacterial infections of the eye or risk of ocular infections.
Types of steroid eye drops are indicated in the conditions of conjunctivitis of the eyelids, conjunctiva of the eyeball, keratitis. This is due to the use of steroids to reduce swelling and inflammation.
Treatment of chronic anterior uveitis and corneal damage caused by chemicals, radiation or thermal burns or foreign bodies.
Concomitant or combined use of a mixed drug with an anti-infective component is indicated when there is a high risk of infection.

Todexe is prepared in the form of an eye drop solution. How to use eye drops 1-2 drops in a period of 4 to 6 hours. During the first 24 to 48 hours, the dose can be increased to 1-2 drops every 2 hours.

Undesirable effects of Todexe include local toxicity in the eyes (including: itching and swelling of the eyelids, redness of the conjunctiva) and toxicity to the vestibule and cochlea (especially for patients with kidney disease).
Similar reactions may occur with treatment with other antibiotics of the Aminoglycoside group.
If Todexe ophthalmic solution is used concurrently with other systemic antibiotics of the Aminoglycoside group, attention should be paid to monitoring serum drug concentrations.
The most common adverse effects of Todexe eye drops containing Dexamethasone are increased intraocular pressure, posterior subcapsular cataracts and delayed wound healing. You need to proactively notify the treating doctor of unwanted effects.

5.1. Contraindications of the drug Todexe People with keratitis caused by epithelial herpes simplex (dendritic keratitis), cowpox, chickenpox, viral infections of the cornea and conjunctiva. Fungal infections of the eye; People with fungal eye disease, corneal ulcer. People with sensitive or hypersensitivity to the ingredients of the preparation. 5.2. Notes and precautions when using Todexe When using Todexe for a long time, there may be a risk of fungal infection of the cornea. Pregnant women and those who are breastfeeding. Subjects are children. 5.3. Use for pregnant and lactating women Pregnant and lactating women use under the direction of the treating physician.
5.4. Effects on Driving and Using Machines Todexe is unlikely to have a significant effect on driving, operating machinery and performing other tasks.
In short, Todexe is an eye drop, used in the treatment of many eye problems. In order for the drug to be used effectively and safely, patients should understand the above information and, if necessary, can consult with doctors and pharmacists.