Uses of Trimespa

Trimespa 100 is a drug that acts on the gastrointestinal tract, often indicated in spasmodic diseases of the gastrointestinal tract. So what disease does Trimespa cure and what should be noted to use the drug to get the best effect?

1. What is Trimespa?

Trimespa 100 has the main ingredient Trimebutine 100mg - a non-competitive antispasmodic agent of the nervous system, stomach - intestines (Meissner plexus, Auerbach); anti-serotonin effect and has affinity for peripheral opiate, kappa, delta receptors, reduces abnormal peristalsis of the gastrointestinal tract; does not change normal bowel movements. In addition, Trimebutine accelerates gastric emptying, stimulates gastro-intestinal peristalsis, regulates contractile activity of the colon; and no adverse effects such as increased sweating or pupil dilation. Trimespa 100 is rapidly absorbed after oral administration, reaching peak plasma concentrations after approximately 1 hour and in the form of minimum 5% plasma protein binding. Drugs metabolized mainly in the liver, rarely cross the placental barrier; The final elimination is mainly in the urine and a small part in the feces (5 - 12%) as metabolites.

2. Indications of Trimespa 100

Trimespa is indicated for the treatment of the following conditions
Irritable bowel syndrome (irritable colon syndrome), colon spasms. Intestinal obstructions, paralytic ileus after surgery, support recovery of intestinal motility after abdominal surgery. Gastrointestinal spasms due to; Gastroesophageal reflux syndrome, hernia fissure, peptic ulcer. Symptoms of gastritis; indigestion, nausea, vomiting. Nausea, vomiting, and non-infectious gastroenteritis cause constipation and diarrhea in children. Biliary spasms due to inflammation or stones.

3. Contraindications of Trimespa 100

Trimespa 100 should not be used in the following cases
Patients who are allergic to Trimebutine or any other ingredient of the drug. Pregnant women and infants are not indicated to use Trimespa. Note when using Trimespa 100:
The drug rarely crosses the placental barrier, but there are still unwanted effects such as miscarriage, birth defects, ... if pregnant women use special drugs especially during the first trimester of pregnancy. Trimespa may be excreted in human milk and safety in children has not been established. Therefore, the benefits should be weighed before using the drug in lactating women.

4. Drug interactions of Trimespa 100

Alcohol, tobacco, alcoholic foods can affect the bioavailability of the drug. Therefore, do not use while being treated with Trimespa 100. No other drug interactions of Trimespa have been detected, but before using in combination with any medicine, you should consult a specialist.

5. Dosage and usage

How to use:
Trimespa 100 is prepared in the form of 100mg film-coated tablets. Swallow the tablet whole with water, do not separate or crush the tablet. Take medicine before meals. Dosage:
Adults: Take 1-2 tablets (100mg)/time x 3 times/day, before meals. Children: Take 5mg/kg/day divided into 3 times. The doctor will prescribe the appropriate dose according to the condition and condition of the patient. If the drug overdose and appear abnormal signs, immediately stop the drug and take the patient to the nearest medical facility for timely treatment. If you miss a dose, take it again as soon as possible. However, if it is almost time for the next dose, skip the missed dose and take the next dose on time. Do not take a double dose of the missed dose.

6. Side effects of Trimespa 100

When using Trimespa 100, you may experience some of the following undesirable effects.
Allergic skin reactions, rash, urticaria. Digestive disorders, dry mouth, thirst, bad breath, indigestion, constipation. Fatigue, drowsiness, fatigue, headache, dizziness, feeling hot and cold. Tachycardia arrhythmia. Increased liver enzymes (SGOT, SGPT). In summary, Trimespa 100 is a drug that reduces spasms of the gastrointestinal tract indicated in diseases and syndromes in the gastrointestinal tract. The drug must be prescribed by a doctor and administered under the supervision of a medical professional.

XEM THÊM:

Bài viết này được viết cho người đọc tại Sài Gòn, Hà Nội, Hồ Chí Minh, Phú Quốc, Nha Trang, Hạ Long, Hải Phòng, Đà Nẵng.