Uses of Tubenarin

Tubenarine is a drug belonging to the group of antiparasitic, anti-infective, antiviral, anti-fungal indicated for the treatment of drug-resistant tuberculosis. To use the drug safely and achieve the best treatment effect, the patient needs to know the information about the drug below.

Tubenarine is a pharmaceutical product manufactured and registered by Dong-A Pharm Co., Ltd, Korea. Tubenarine belongs to the group of antiparasitic, anti-infective, antiviral and antifungal drugs with the main active ingredient being Cycloserine 250mg. The drug is indicated for the treatment of patients with drug-resistant pulmonary tuberculosis.
Tubenarine is in the form of hard capsules and is packaged in a box of 3 blisters x 10 tablets, each containing 205mg of cycloserin and excipients just enough.

2.1. What does Tubenarine do? Tubenarine medicine contains the main ingredient is the antibiotic Cycloserine, an antibiotic synthesized by chemical method from Streptomyces orchidaceus. The drug has the effect of inhibiting the growth of some bacteria such as Enterococcus, Escherichia coli (E.coli), Nocardia...
Tubenarine is prescribed by medical experts and doctors to be used concurrently with other drugs. other TB treatment in order to increase the effectiveness of TB treatment and limit the status of drug-resistant TB bacteria.
2.2. Indications for Tubenarine Drugs Tubenarine is indicated in the following cases:
Used in combination with other anti-tuberculosis drugs to treat drug-resistant tuberculosis. Besides, the drug is also indicated in cases of urinary tract infections. 2.3. Tubenarine is contraindicated in one of the following cases:
Patients with allergies, hypersensitivity to the Cycloserine component of the drug or other excipients included in the formula. The patient has severe renal failure. The patient has a history of epilepsy, psychosis, depression, severe anxiety. Do not use the drug in patients with alcohol dependence.

When using Tubenarine, the patient needs to follow the way of use, the dose as prescribed and the instructions of the doctor, medical professional and the manufacturer.
Usage:
The drug is taken orally along with other TB medicines. Tablets should be taken whole with boiled or purified water. Do not take the medicine together with alcohol, beer, coffee, carbonated drinks, soft drinks, bottled fruit juices... And when drinking, the patient should not chew, break, crush or disperse the medicine because it will cause harm. change the composition of Tubenarine affecting the treatment process. Dosage:
The dose of the drug depends on the purpose of treatment, the progression of the disease, the response of the patient, which is different, namely:
Treatment of tuberculosis in adults and children from 12 years of age and older. Up: The starting dose is 250mg/time x 2 times/day and maintained for the first 2 weeks. Time after dose adjustment so that the drug concentration in the blood when there is a response, up to a maximum of 500mg every 12 hours (highest daily dose 15-20mg/kg). Treatment of tuberculosis in children under 12 years of age: The starting dose is 10mg/kg body weight/day and the dose is adjusted according to the drug concentration in the blood, as well as the response of the drug. Treatment of urinary tract infections: Use 250mg/time x 2 times/day and maintain continuously for 2 weeks. Note: It is necessary to monitor drug levels in the blood, especially for people with kidney failure or when the dose exceeds 500mg/day or there are signs of drug poisoning. Note that the drug concentration in the blood should not exceed 30 micrograms/ml.

When using Tubenarine medicine can cause some side effects from mild to dangerous such as:
Headache, dizziness, dizziness, tremor, excitement, panic, paranoia, anger. Loss of vision, lightheadedness, anxiety, depression, anxiety, fear, convulsions. Irritation, erythema, decreased absorption of calcium, magnesium, decreased protein synthesis Folic acid and vitamin B12 deficiency, arrhythmia. More seriously, you can go into a coma or have a stroke. Attention: If you experience the above undesirable effects or have other unusual signs not mentioned. Patients should notify their doctor or healthcare professional immediately for advice on safe and effective management.

Tubenarine can interact with some other drugs when taken at the same time. This drug interaction can be synergistic or antagonistic, but both affect the action of the drug or increase the severity of the side effects.
Therefore, the patient should list and show the treating doctor the list of drugs, functional foods and herbs being used. This helps the doctor adjust the dose or prescribe an alternative medicine suitable for the patient to avoid drug interactions.
Some drugs and food drug interactions with Tubenarine include:
When used concurrently with Isoniazid or Ethionamide will increase the risk of toxicity to the nervous system. Drinking alcohol while taking the drug increases the risk of seizures and seizures.

In order to use Tubenarine drug to achieve the best effect and safety when using, the patient should also note and be careful:
Be careful for patients taking more than 500mg Cycloserin/day Adjust the dose of drug concentration in the blood Less than 30 micrograms/ml It is necessary to strictly follow the instructions of the doctor and medical professional in the process of taking the drug, not to increase or decrease the dose of the drug to be effective quickly. Before being prescribed medication, the patient needs to inform the doctor about his current condition, history of chronic diseases such as heart disease, allergies... so that the doctor can advise and change the dose if necessary, needs. Patients should minimize foods, beverages containing alcohol or stimulants during drug treatment. Use extreme caution in pregnant or lactating women. It is best for these subjects not to take the drug, if necessary, it is necessary to weigh the risks and benefits, as well as strictly follow the doctor's instructions. The drug can cause drowsiness, so do not use while driving or operating machinery.

Missed dose: If you forget to take a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next dose as directed. Absolutely do not take 2 doses together to avoid overdose and increase side effects.
Overdose: When taking an overdose of the drug, the patient may experience some symptoms such as headache, dizziness, somnolence, confusion, excitability, paresthesia and psychosis, even with higher doses. convulsions or coma may occur.
Overdose treatment: When there are signs of overdose, it is necessary to contact a doctor or take the patient to the nearest medical center for emergency treatment and timely treatment.

Medicines should be stored in a dry place with a temperature of 15-30 degrees Celsius, avoid storing the medicine in humid places or in direct sunlight. Keep medicine out of sight and reach of small children and pets. For expired medicines, which cannot be used anymore, collect and dispose of waste according to the instructions of your doctor or local waste disposal company to ensure safe disposal of the medicine. Do not throw the medicine into the toilet or flush it under the household tap. Above is information about the uses, how to use Tubenarine and the notes and cautions when using it. This information is for informational purposes only and is not intended for professional medical treatment. Therefore, before using the drug, the patient should contact the doctor, medical professional for advice and appropriate indications and safe use of the drug.