Uses of Usamuc

Each 1.5g pack of Usamuc contains Acetylcysteine ​​200mg and excipients just enough. Acetylcysteine ​​is a mucolytic agent. Acetylcysteine ​​(N - acetylcysteine) is an N - acetyl derivative of L - cysteine, a natural amino - acid. Acetylcysteine ​​is used as a mucolytic and antidote for paracetamol overdose. The drug is used to reduce the viscosity of sputum in the lungs by cleaving the disulfide bridge in the mucoprotein and to facilitate the removal of sputum by coughing, orthostatic drainage or by mechanical means.
Acetylcysteine ​​is also used topically for tear-free treatment. Acetylcysteine ​​is used to protect against hepatotoxicity caused by paracetamol overdose by restoring or maintaining hepatic glutathione concentrations, which are important for inactivation of the hepatotoxic intermediate metabolite of paracetamol. In the case of paracetamol overdose, this metabolite is produced in large quantities, as the main metabolite (glucuronide and sulfate conjugates) becomes saturated. Acetylcysteine ​​is converted to cysteine, which stimulates the liver to synthesize glutathione to protect the liver if treatment is started within 12 hours of paracetamol overdose. Therefore, starting treatment with Usamuc as soon as possible is highly effective.
Indications : Usamuc is used to clear mucus in acute and chronic bronchial - lung diseases accompanied by increased mucus secretion; Contraindications: Do not use Usamuc for people who are hypersensitive to Acetylcysteine ​​or any of the ingredients in the drug.

How to use: Use Usamuc orally, dissolve the drug in water and then drink.
Dosage : Without other instructions from a qualified doctor, the usual dose of Usamuc is as follows:
Adults and children from 7 years of age and older: 200mg x 2 - 3 times/day; Children from 2 to 7 years old: 200mg x 2 times/day; Children under 02 years old: 100mg x 2 times/day; As an antidote in the treatment of overdose Paracetamol: The starting dose is 140 mg/kg, followed by a dose of 70 mg/kg every 4 hours and a total of 17 more times; Note: Acetylcysteine ​​is most effective when taken within 8 hours of a paracetamol overdose. After this time, the effect will gradually decrease. However, if treatment is started more than 24 hours later, it may still be effective.

Some undesirable effects when using the drug Usamuc are:
Very rare: stomatitis, tinnitus, digestive disorders; Hypersensitivity reactions: Angioedema, hypotension, rash and pruritus, bronchospasm, sometimes with a risk of hypertension; Some other undesirable effects: Nausea, vomiting, flushing, fever, sweating, fainting, blurred vision, joint pain, liver dysfunction, convulsions, acidosis, respiratory arrest.

Some things patients need to keep in mind before and while using Usamuc:
During pregnancy: Treatment of paracetamol overdose with acetylcysteine ​​in pregnant women is effective, safe and has the ability to prevent toxic effects. calculated for the liver in the fetus and also in the mother; Lactation: Usamuc can be used during breast-feeding.

Some drug interactions Usamuc patients should note are:
Should take tetracyclines away from the time of taking Acetylcysteine ​​at least 2 hours; Usamuc should not be used concurrently with cough medicines, because it can cause severe mucus congestion due to the cough reflex, so consult a medical professional before combining use; Acetylcysteine ​​may potentiate the vasodilator and platelet aggregation inhibitory effects of nitroglycerin; Acetylcysteine ​​is a reducing agent, so it should not be combined with oxidizing agents to ensure safe and effective use. Users should pay attention to listen and follow the instructions of the doctor when using Usamuc to be able to achieve high treatment efficiency and limit unwanted side effects.
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