Uses of Vipanzole

Vipanzol drug is a drug used in gastrointestinal diseases such as peptic ulcer disease, diseases that cause increased secretion of gastric juice... The main ingredient is Pantoprazole salt form Pantoprazole sodium sesquihydrate. For more information about Vipanzol, please read the following article.

Vipanzol contains 1 vial of Pantoprazole lyophilized powder, a proton pump inhibitor, and 1 tube of 0.9% NaCl solvent 10ml. The drug works to treat diseases related to acidic gastric juices of the gastrointestinal tract thanks to the mechanism of the drug pantoprazole contained in the drug.

2.1. Indications Vipanzol is indicated in gastrointestinal diseases such as:
Gastroesophageal reflux disease, which causes increased secretion of gastric juice. Prophylaxis and treatment of gastric ulcer, duodenal ulcer caused by taking anti-inflammatory drugs or treating diseases. Zollinger - Ellison syndrome has symptoms of increased gastric acid secretion. 2.2. Contraindications Do not use Vipanzol in patients with a history of allergy or hypersensitivity to Pantoprazole.

3.1. How to use Vipanzol by intravenous injection or intravenous infusion.
How to make intravenous solution: Mix vial of Vipanzol lyophilized 40ml with 10ml of 0.9% NaCl in the accompanying tube. How to prepare solution for intravenous infusion: Dissolve vial of Vipanzol lyophilized in 100ml of solution for infusion. Vipanzol infusion solution can be 0.9% NaCl, 5% dextran solution or Ringer Lactate isotonic solution. Note: When diluting the solution, a precipitate may be found, this does not change the amount of drug in the solution, the solution must be passed through the filter of the infusion line, must be administered separately, not with the infusion. other infusion solutions. The diluted solution should be used within 6 hours. The solution should be administered intravenously slowly, over at least 2 minutes. The intravenous line is preferred in cases of severe disease such as active gastric bleeding and is given over a minimum of 15 minutes.
3.2. Dosage Depending on the clinical situation, Vipanzol is indicated with different doses and duration. The following are the therapeutic dose recommendations from the manufacturer, you can refer to:
In gastroesophageal reflux disease, gastric ulcer, duodenal ulcer: Once a day, 40mg of pantoprazol each time. Diseases causing increased gastric juice, Zollinger - Ellison syndrome: Initial daily starting dose of 80mg, in case of need to control acid quickly, can use up to 160mg. Divide 2 times a day. After dose reduction according to patient response, maintain daily dose of 80mg.
The maximum dose of the drug in 1 day is 240mg.
Patients with severe liver failure: Reduce the dose of pantoprazole or use it every other day. The maximum daily dose is 20mg or 1 dose of 40mg in two days.
People with impaired renal function: No dose adjustment is required. Children: The safety and efficacy of pantoprazole have not been established.

The drug is well tolerated in both short-term and long-term treatment. Side effects when using Vipanzol may be as follows:
The drug reduces the acidity in the stomach, which may increase the risk of gastrointestinal infections. Common side effects include systemic symptoms such as fatigue, headache, and dizziness. Red rash on the skin, urticaria. Musculoskeletal pain with muscle fatigue. On the digestive tract causes anorexia, bloating, vomiting. digestive disorders constipation diarrhea, dry mouth. Uncommon: Systemic symptoms causing insomnia, dizziness, weakness, dizziness. On the skin with symptoms of itching, the test has increased liver enzymes. Rarely systemic with: Anaphylaxis, sweating, malaise, peripheral edema. Skin: Acne, maculopapular rash, alopecia, erythema multiforme, angioedema, exfoliative dermatitis. On the digestive system: belching, stomatitis due to less saliva, digestive disorders... The above are some common, uncommon and rare side effects when using Vipanzol. If the patient has any of the above signs or other uncomfortable signs, please contact the treating doctor immediately to notify in time, to avoid complications when taking the drug.

It is necessary to tell the name of the drugs and functional foods you are taking to the treating doctor, because the drug interacts with certain drug groups. Like the drugs Ketoconazole, Itraconazole, Methotrexate when used together with pantoprazol cause undesirable effects. There were no clinically significant interactions between Vipanzol and commonly used drugs such as nifedipine, diazepam, phenytoin, theophylline, digoxin, oral contraceptives, warfarin anticoagulants.
Before taking pantoprazol, the patient should be excluded the possibility of stomach cancer, because drugs that increase the pH of the stomach can increase the possibility of cancer.
For patients with liver disease (acute, chronic, history) should be cautious when using pantoprazol. The drug concentration in the blood may increase slightly and reduce the elimination slightly, no dose adjustment is required. Using the drug when having cirrhosis, severe liver failure, it is necessary to reduce the dose or use it once a day and monitor the liver function tests regularly.
Use Vipanzol with caution in the elderly and people with kidney failure.
After using the drug effectively, the doctor may consider switching to oral tablet form while still maximizing the therapeutic effect.
Cases of overdose: uncommon and underreported. Signs of overdose may be drowsiness, slightly tachycardia, headache, vasodilatation, confusion, nausea, blurred vision, abdominal pain, vomiting. Treatment: gastric lavage, use activated charcoal to detoxify, treat symptoms, monitor heart activity, regularly measure blood pressure. In case of prolonged vomiting, the condition must be monitored and rehydrated, electrolytes should be rehydrated.
There are no adequate studies when using Vipanzol in humans during pregnancy. Animal studies have shown that the drug crosses the placental barrier, but no teratogenic effects have been observed in the fetus. Using a dose of 15 mg/kg slows fetal bone growth. Vipanzol should only be used when clearly needed in humans during pregnancy.
It is not known whether the drug is excreted in human milk. According to the study of pantoprazol and its metabolites in the milk of rats. Based on the drug's carcinogenic potential in rats, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the benefit of pantoprazole to the mother.
Be careful when patients drive and operate machinery because side effects of the drug can cause dizziness, headache, blurred vision.
Vipanzol is a prescription drug used by the doctor's prescription, the patient should not take it on his own. If you still have questions about drug use, unwanted effects, indications of Vipanzol, you should directly visit and listen to advice from a specialist doctor or pharmacist.