Uses of Viprazo

Viprazo is a gastrointestinal drug, the main ingredient is Omeprazol, 40mg content, prepared in the form of lyophilized powder for injection, packed in a box of 1 vial and 1 ampoule of 10 ml solvent. Drugs used in gastrointestinal diseases such as duodenal ulcer, gastric ulcer, Zollinger-Ellison syndrome...

The use of Viprazo is used to treat diseases of the digestive tract, when other methods are not effective or in an emergency. The drug contains 40mg of the main active ingredient Omeprazole.
Pharmaceutical substance Omeprazole participates in specific inhibition of the effect through blocking the proton pump system H + K + ATPase of the parietal cells of the gastrointestinal tract. The drug acts on the last stage of acid secretion, a single dose of Omeprazole 20mg per day rapidly inhibits gastric secretion due to any stimulus. Omeprazole has no effect on acetylcholine or histamine receptors and has no significant pharmacokinetic effects other than those on acid secretion. The drug causes a long-term decrease in gastric juice, but is reversible. After 5 days of discontinuation of the drug, gastric secretion returned to normal, but no increase in acid secretion appeared. According to endoscopic examination results, the scar wall rate of duodenal ulcers reached 65% after 2 weeks of treatment and reached 95% after 4 weeks of treatment. The drug is destroyed in an acidic environment. After injection, drug levels appear in the blood. Concomitant food absorption with Omeprazole injection has no effect on bioavailability. Approximately 95% of the drug concentration of Omeprazole is bound to plasma proteins, mainly to albumin. Viprazo is subject to changes in the liver. The inactive metabolites present in plasma are sulfides, sulfones and hydroxy omeprazole. 80% of the metabolites (hydroxy-omeprazole and corresponding carboxylic acid) are excreted in the urine. 20% of the metabolites of Viprazo drug are excreted in the feces.

2.1. Indications for Viprazo Drugs Viprazo drugs are used in the following diseases:
Duodenal ulcer; Stomach ulcers ; esophagitis with ulceration; Used to treat Zollinger-Ellison syndrome. 2.2. Contraindications to the drug Viprazo Do not use Viprazo in cases where the patient is allergic to the drug Omeprazole contained in the drug and other excipients.

How to use: Viprazo is used intravenously slowly, injection time is not less than 2.5 minutes, injection rate is not more than 4mL/min.
Dilute Viprazo lyophilized vial with 10mL of solvent available in vial.
Dosage: Patients need to adhere to the dose of Viprazo drug from the treating doctor or refer to the following drug dosage:
40mg injection dose per day, taking a single dose. When additional intravenous administration of the drug is required for 3 days, the dose should be reduced to 10 mg to 20 mg per day. Dosage in Zollinger-Ellison syndrome: patients need to be adjusted according to individual patient response. Note that there is no need to adjust the dose of Viprazo in patients with liver failure, kidney failure, elderly subjects. Overdose: It is necessary to immediately notify the doctor, medical staff when the patient uses the drug in excess of the prescribed dose and shows unusual signs.

Patients may experience undesirable effects after injecting Viprazo such as: Headache, diarrhea or constipation, abdominal pain, nausea or vomiting, upper respiratory tract infection, dizziness face, urticaria, cough, whole body weakness, back pain.
When experiencing the above undesirable effects or the patient sees any other unusual symptoms during the use of Viprazo, please inform the treating doctor.

When patients are prescribed Viprazo drug, it is necessary to note the following issues:
Drug interactions: When used with Viprazo, it may increase the concentration of Diazepam, Phenytoin and Warfarin anticoagulants in the blood plasma. . The possibility that the patient has a gastrointestinal malignancy should be excluded before being treated with other laboratory tests. The drug is administered by injection directly into the vein for subjects with severe disease, people with many ulcers or when they do not respond to oral tablets. The patient needs to be injected with Viprazo slowly intravenously. The dose of 40mg drug after intravenous injection will immediately reduce the amount of hydrochloric acid (HCl) in the stomach within 1 day. For patients with severe liver disease, it is necessary to reduce the dose of Viprazo 20mg per day. Consider Viprazo in pregnant women. Viprazo should not be used during breastfeeding because it may cause adverse effects on the neonate. The effects of Viprazo do not affect the ability to drive, use machines or when people are sick. traffic disease. Above is information about the use of Viprazo drug. This is a prescription drug for intravenous use, to treat diseases with increased acid secretion. The drug is not used for a long time, the patient needs to follow the instructions from the doctor. If the patient has any questions about Viprazo, please consult with experienced doctors, pharmacists and medical staff.