Uses of Zidocat

The Cefuroxime component in Zidocat is a broad-spectrum semi-synthetic antibiotic. The drug belongs to the group of cephalosporin antibiotics.
Cefuroxime axetil is a prodrug of cefuroxime, which has very little antibacterial activity when it is not hydrolyzed to cefuroxime in the body after absorption.
Cefuroxime has antibacterial activity by inhibiting bacterial cell wall synthesis by binding to essential target proteins (penicillin-binding proteins).
Therefore, Zidocat is indicated in mild to moderate infections such as:
Lower respiratory tract infections with manifestations of pneumonia, acute and chronic bronchitis. Upper respiratory tract infections such as ear, nose and throat infections such as otitis media, sinusitis, tonsillitis, pharyngitis. Urogenital infections: pyelonephritis, cystitis, urethritis, skin and soft tissue infections such as boils, pustules, impetigo. Gonorrhea Skin infections such as: boils, pyoderma, impetigo. On the other hand, this drug is not indicated for prescription in case the patient is sensitive to any ingredient of the drug.

Zidocat is recommended for oral administration. The usual course of treatment is 7 days, if after this time, the condition does not improve or shows signs of worsening, the patient should notify the doctor.
Dosage of the drug will vary based on the age, health status of the patient as well as the purpose of treatment. Patients can refer to the dosage below:
Dosage for adults:
Treatment of pharyngitis, tonsillitis or maxillary sinusitis caused by sensitive bacteria, the dose is 250mg/time. Drink 2 times a day. For the treatment of acute exacerbations of chronic bronchitis or acute bronchitis secondary to infections or in uncomplicated skin and soft tissue infections, 250mg or 500mg once. Drink 2 times a day. Treatment of uncomplicated urinary tract infections indicated a dose of 125mg or 250mg, twice a day. Dosage for children:
To treat pharyngitis, tonsillitis: 20mg/kg/day (maximum 500mg/day) divided into 2 small doses. Treatment of otitis media, impetigo: 30mg/kg/day (maximum 1g/day) divided into 2 small doses. If you forget to take a dose of Zidocat, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and take the next dose as scheduled.
There have been cases of overdose Zidocat with symptoms such as: nausea, diarrhea, abdominal pain ... Some cases occurred nerve stimulation reactions with convulsions. This condition often occurs in patients with kidney failure with bacterial infections.
When falling into this situation, the patient needs to stop using the drug, anticonvulsant therapy can be used if clinically indicated. Hemodialysis can remove drugs from the blood, but most treatment is supportive or symptomatic.

Before prescribing, the doctor has considered the benefits and risks that the drug brings to the patient, however, Zidocat still has the risk of causing side effects. The adverse reactions are:
Common: Diarrhea, Erythematous rash... Uncommon: Anaphylaxis, Candida infection, neutropenia, positive Coombs test, urticaria, pruritus ... Rare: Fever, anemia, hemolysis, pseudomembranous colitis, cholestatic jaundice, mild elevation of AST, ALT.... According to reports, common side effects tend to disappear on their own. after a few days or weeks. Meanwhile, serious reactions can develop and threaten the health of the user. With serious side effects, the doctor may order treatment to improve the situation.

There have been recorded drug interactions between Zidocat and some drugs such as Ranitidine, Sodium bicarbonate, Cefuroxim acetil, Probenecid, Aminoglycoside ...
This situation is understood as the interaction between this drug and other drugs. The result of this process will make the drug increase or decrease the therapeutic effect, or give rise to some unwanted effects that are detrimental to the patient.
To avoid this situation, the patient actively informs the doctor about the used drugs before prescribing. From there, the doctor will decide whether to prescribe Zidocat or not. In case of prescription, it is necessary to change the dose or time of taking these drugs.

Safe use of drugs helps to maximize the effectiveness of the drug during the treatment of infection symptoms. Therefore, the patient should "take to heart" the following notes:
Exploit, consider the patient's allergy to Cephalosporin, penicillin or other drugs. Because Zidocat has the ability to cross infection. During treatment with Zidocat, patients need to monitor and evaluate kidney function regularly, especially in the case of taking the maximum dose. At the same time, Zidocat should be used with caution with diuretics to reduce the risk of adverse effects on renal function. Zidocat should only be used for a period of 7 days. Long-term drug abuse will facilitate the overgrowth of non-susceptible strains. In case of severe superinfection during treatment, the drug must be discontinued. Use of the broad-spectrum antibiotic Cefuroxime increases the risk of pseudomembranous colitis. Increased nephrotoxicity has been reported with concomitant administration of Aminoglycoside and Cephalosporin antibiotics. Women who are in pregnancy can safely use Cefuroxime. Zidocat may pass into lactose at low concentrations. Women who are breastfeeding can still be treated with this medicine. However, it is necessary to monitor for diarrhea in young children. Always store the medicine properly so as not to reduce the effectiveness of the treatment. Accordingly, each drug will have different ways of preservation, so patients need to carefully read the instructions on the storage information of the medicine written on the box and read the instructions for use of the medicine. Avoid direct exposure to sunlight or high temperatures, which can convert the ingredients in Zidocat. In short, Zidocat is a prescription drug that should be used exactly as prescribed by a doctor. When there are any unusual signs that are suspected to be due to drug use, you also need to consult your doctor for answers to questions as well as timely treatment measures.
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