Uses of Zinextra

Zinextra drug belongs to the group of parasitic, anti-infective, antibacterial, antifungal drugs, used to treat urinary tract infections, respiratory tract infections and skin and soft tissue infections. Zinextra is a drug that is used under the direction of a treating doctor.

Zinextra medicine has the main active ingredient Cefadroxil Monohydrate and other excipients just enough. Zinextra drug is prepared in the form of powder for suspension, packed in boxes, each box includes 1 vial containing powder for mixing 100ml of suspension and a measuring cup of 10ml.

Zinextra is used to treat the following cases:
People with urinary tract infections: urethritis, cystitis, acute and chronic pyelonephritis People with respiratory tract infections: Inflammation pharyngitis, tonsillitis, bronchopneumonia and lobar pneumonia, lung abscess, acute and chronic bronchitis, pleurisy, empyema, otitis media, laryngitis. People with skin and soft tissue infections: Abscess, cellulitis, ulcers, lymphadenitis People with osteomyelitis, arthritis and bacterial infections.

Zinextra is contraindicated for use in people who are allergic or hypersensitive to Cephalosporin antibiotics.
Note: Cases of contraindications to the use of Zinextra are absolute contraindications, ie not for any reason that the above cases are flexible to use the drug.

How to use: Zinextra drug is prepared as a powder for suspension, so it should be used orally. The user dissolves 100ml of drug suspension with 10ml of water in the measuring cup provided in the medicine box. Should be taken when the suspension is completely dissolved and should be used immediately after mixing, avoid leaving too long in the air to affect the ingredients in the medicine.
Dosage: Patients can refer to the dose of Zinextra below:
For adults: Take a dose of 500 - 1000mg / time, can be used from 1 to 2 times a day depending on the level of infection of the patient. . For children under 6 years of age: 500mg x 2 times/day For children aged 1 to 6 years: 250mg x 2 times/day For the elderly and patients with renal failure: Need to be Dosage adjustment when using Zinextra In case of renal failure: Using a starting dose of 500 - 1000mg Cefadroxil, the next dose can be adjusted as follows: People with renal impairment have a creatinine clearance of 0-1000mg. 10ml/min: 500-1000mg for the starting dose and 500mg for the maintenance dose, each dose taken 36 hours apart. Patients with renal impairment with creatinine clearance between 10-25ml/min: 500-1000mg for the starting dose and 500mg for the maintenance dose, each dose taken 24 hours apart. People with renal failure have creatinine clearance from 25 - 50ml/min: Use 500 - 1000mg for the starting dose and 500mg for the maintenance dose, each dose taken 12 hours apart. In case of missed dose of Zinextra: Users should use Zinextra regularly to get the best effect. However, if you miss a dose, skip the missed dose and continue with the next dose exactly as directed by your doctor. Patients should absolutely not use double the dose to make up for the forgotten dose, to avoid leading to overdose.
In case of overdose: If the patient uses an overdose of Zinextra for a long time, it can lead to convulsions. When detecting an overdose, the user should immediately inform the doctor about the amount of Zinextra he has taken and his current health so that the doctor can quickly handle it.

During the use of Zinextra, in addition to the main use that the drug brings, the patient may also experience some unwanted symptoms as follows:
Common symptoms: Effects on the digestive system: Nausea, Vomiting, diarrhea, abdominal pain Uncommon symptoms: Effects on blood: Elevated eosinophils Skin effects: Skin rash, urticaria, pruritus, maculopapular rash Effects on liver: Increases Transaminase Reversible Genitourinary tract effects: Vaginitis, testicular pain, genital itching, candidiasis Rare symptoms: Systemic effects: anaphylactic reactions, fever , serum sickness Effects on blood: Thrombocytopenia, neutropenia, hemolytic anemia, positive Coombs test Gastrointestinal system effects: Gastrointestinal disturbances, pseudomembranous colitis Affects Skin: Stevens-Johnson syndrome, common pemphigus, erythema multiforme, toxic epidermal necrolysis (Lyell's syndrome), angioedema. Effects on the liver: Hepatitis, cholestatic jaundice, slight increase in AST, ALT indexes. Effects on the kidneys: Reversible interstitial nephritis, nephrotoxicity with a temporary increase in blood urea and creatinine levels Central nervous system effects: Causes headaches, agitation or convulsions with high doses. and when renal function is impaired. Effects on other parts: Causes joint pain How to handle when strange symptoms appear during the use of Zinextra:
Users need to immediately inform their doctor about their current condition for advice. on how best to treat unwanted symptoms Stop taking Cefadroxil immediately. In case of severe allergic or hypersensitivity reaction, the patient should receive supportive treatment with the following methods: Maintain ventilation and use adrenaline, antihistamines, oxygen, intravenous corticosteroids. For people with mild pseudomembranous colitis: Usually just stopping the drug. For people with moderate to severe pseudomembranous colitis: Need to add fluids and electrolytes, supplement protein and take Metronidazol.

When using the drug, patients need to keep in mind some reactions that occur between Zinextra with other drugs as follows:
Simultaneously combine Zinextra with potassium-sparing diuretics or potassium supplements, substances Potassium-containing salt substitutes: may lead to increased serum potassium and increased serum creatinine in individuals with heart failure. Combination with Cholestyramine with Cefadroxil in the intestine: Slows down the absorption of the drug. Combined with probenecid: Can reduce the excretion of Cefadroxil Combined with furosemide, aminoglycoside: may cause synergistic increase of nephrotoxicity. Note: To minimize the unfortunate interactions that occur when using Zinextra, the patient needs to inform the doctor about the drugs, dietary supplements, vitamins and minerals that he is using or taking. intention to combine with the drug to get the best advice on the course of treatment.

Patients should note a few things when using Zinextra:
Care should be taken when using the drug for people who are allergic or hypersensitive to penicillin antibiotics, people with kidney failure, people with gastrointestinal diseases , women who are pregnant or in the process of breastfeeding. Limit long-term use of Cefadroxil because it may cause overgrowth of non-susceptible strains. This case should be carefully monitored, if superinfection occurs, Zinextra should be discontinued immediately. Zinextra is a prescription drug, so patients should not use it on their own, but need to contact a doctor / pharmacist directly to get a suitable prescription and ensure safety for health. Hopefully, the information shared above will help users have more useful knowledge to use Zinextra effectively in the treatment of urinary tract infections, respiratory infections and infections. skin and soft tissue bacteria.