What does Acnotin 10 do?

Acnotin 10mg is a brand name drug specifically indicated for severe acne and has not responded to other conventional therapies. In this article, more specific information such as what acnotin 10 does and how to take it will be provided to readers.

Acnotin 10 is an acne medicine from the manufacturer Mega Lifesciences - a famous pharmaceutical company in Thailand. Currently, this pharmaceutical company and their products have appeared in nearly 40 countries around the world. In Vietnam, Mega Lifesciences has been operating since 1995 with a series of quality healthcare solutions such as Eugica, Ferrovit, Nac C...
The main ingredient of Acnotin in general is Isotretinoin and this substance accounts for the function. Very high amount in one capsule. Thus, each Acnotin 10 mg tablet will contain 10 mg of the active ingredient Isotretinoin, while each Acnotin 20 mg tablet will contain 20 mg of the active ingredient Isotretinoin. In addition, each tablet is also added some other excipients such as white beeswax, butylated hydroxyanisole, soybean oil, brilliant blue, disodium edetat, sorbitol 76%... Currently, Acnotin has only two forms. The main ingredients are Acnotin 10 and Acnotin 20.
Regarding the effect of the active ingredient Isotretinoin, this is an active ingredient known for its ability to reduce the size as well as inhibit the activity of the sebaceous glands on the skin, thereby reducing possibility of acne. Besides, the active ingredient isotretinoin also has strong anti-inflammatory properties.
Currently, the market price of each box of Acnotin 10 is 280,000 VND, each box is designed into 3 blisters, 10 tablets each, for a total of 30 tablets.

Drugs Acnotin 10 or Acnotin 20 are often prescribed when patients need to treat problems such as:
Generalized acne. Severe acne that has not responded well to other conventional treatments. Acne causes facial disfigurement and leaves deep scars, Acne lasts for many years, negatively affects psychology, communication, daily life and hinders opportunities at work . Besides, the drug also has a number of other approved effects but not mentioned on the drug label. In this case, the doctor will prescribe a more specific use.

3.1. Instructions on how to take the drug Acnotin 10 Acnotin 10 should be taken with a meal and taken as a whole tablet, absolutely do not chew or crush the tablet, because it can reduce the content of Isotretinoin, making the effectiveness of the drug not reach the level. maximum. In addition, during the period of acne treatment with Acnotin, you should limit exposure to the sun and do not use Acnotin 10 simultaneously with acne medications that have the ability to peel off the skin. or keratolytic of the skin, whether oral or topical.
The effectiveness of treatment with Acnotin 10 can vary depending on the individual patient's condition, usually lasting about 16 weeks. At the beginning of using the drug, the number of acne may be more than the current condition but quickly improve. Sometimes, to increase the effect, you need to combine with adrenocorticoids. The effectiveness of Acnotin 10 will be evaluated when the acne condition still improves after stopping using the drug for a while. Therefore, a discontinuation period is usually required for at least 8 weeks before repeated use of Acnotin 10 to observe efficacy.
3.2. What is the usual dose of Acnotin 10? In adults and adolescents, the general dose of Acnotin is 0.5 to 1 mg per kg of body weight daily. For example, your weight is 50kg, you need to take from 25mg to 50mg of Acnotin / day, equivalent to 2 - 3 10mg Acnotin tablets. The number of pills will not be taken at the same time, but divided into 2 times per day and used continuously for 15 to 20 weeks.
In the case of severe acne or acne appearing on the back, chest... the doctor may prescribe a higher dose of Acnotin 10 mg, but the maximum is 2mg per kg of body weight. It should be noted that Acnotin is a drug that should not be used in children under 12 years of age.

When taking an overdose of Acnotin indicated, your body will go into a state of excess vitamin A with common manifestations of dizziness, abdominal pain, headache, nausea and vomiting, increased pressure in the internal organs. skull, especially the outer skin will be irritated, red, itchy. When symptoms of Acnotin overdose occur, you need to stop taking the drug immediately and notify your doctor.

Acnotin 10 side effects are generally tolerable when used in usual doses. However, if you arbitrarily increase the dosage, the bigger side effects that can occur besides the problem of excess vitamin A are:
Painful itching and dermatitis, inflammation around the nails, hair loss, appearance of many acne acne and hyperpigmentation, more sensitive to light. Musculoskeletal pain, tendonitis, bone proliferation. There are behavioral disturbances, headaches, epilepsy and depression. Hearing impairment, visual field disturbance and shadow adaptation disorder, keratitis, cataract. Inflammation of the colon, colon and ileum, gastrointestinal bleeding. Hepatitis , transient elevation of liver enzymes, bronchospasm. Decreased white blood cells and red blood cells, possibly increased or decreased platelet count. Increased likelihood of local or systemic infections associated with Staphylococcus aureus...

Although it is an acne medicine, Acnotin 10 still has important contraindications (not to be used) such as:
People who are allergic to the ingredients in Acnotin, especially isotretinoin. People with impaired liver or kidney function, hyperlipidemia, signs of vitamin A toxicity. Women who are pregnant, breastfeeding, or planning to become pregnant...

Not only Acnotin 10, but for Acnotin drugs in general, to ensure safety, you need to pay attention to the following issues:
If acne is caused by Androgen hormone, you should not use the drug simultaneously with oral contraceptives containing the androgen progesterone. While using Acnotin 10 and within 5 to 6 months after stopping the drug, facial treatments (non-metallic, peels, etc.) should not be performed as this will increase the risk of keloid formation. Hair removal waxes should also be avoided during acne treatment with Acnotin, as this can increase the risk of skin inflammation. Absolutely do not use Acnotin 10 or Acnotin in general for pregnant women as well as planning to become pregnant, because the drug ingredients can cause malformations and abnormalities for the fetus. Besides, isotretinoin is also easily excreted into breast milk, so nursing mothers should also avoid using this drug.

First of all, the effectiveness of Acnotin 10 may be reduced by drinking alcohol. Therefore, you should abstain or completely stop consuming alcohol during treatment with the drug. In addition, the concomitant use of Acnotin with the following substances should be avoided:
Vitamin A: increases the likelihood of the patient having an excess of vitamin A. The drugs of the tetracycline and minocycline groups can lead to increased intracellular pressure. skull and causes headache, vomiting, and angioedema. Low-dose progesterone and phenytoin also reduce the effect of acnotin. Ketoconazole increases blood corticosteroid concentrations when used together with Acnotin. In addition, before using Acnotin 10, it is necessary to stop topical products containing benzoyl peroxide, tretinoin, sulfur...
It can be said that Acnotin 10 is a type of acne treatment that is usually indicated for the condition. severe acne or generalized acne when no other treatment can be used. You absolutely should not arbitrarily use the drug to avoid unwanted risks.
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