What is Bicarfen 200 used for?

Bicarfen 200 is the main ingredient of Ibuprofen 200 mg, belongs to the group of non-steroidal anti-inflammatory drugs (NSAIDs). Bicarfen 200 is used in the treatment of mild to moderate pain, anti-inflammatory and antipyretic. Thoroughly understanding the necessary information such as ingredients, uses, doses and side effects of Bicarfen 200 will bring patients the best treatment effect.

Bicarfen 200 is prepared under effervescent tablets, with the main ingredients including:
Active ingredient: Ibuprofen 200mg. Excipients: citric acid, sodium carbonate, sodium bicarbonate, sodium citrate, Acesulfam K, Tween 80, HPMC, Simethicone, PEG 6000, Lemon scent just enough for 1 effervescent tablet 200mg. Pharmacodynamics
Ibuprofen is a derivative of propionic acid, which belongs to the group of non-steroidal anti-inflammatory drugs (NSAIDs). The mechanism of Ibuprofen's antipyretic, analgesic and anti-inflammatory effects is to prevent the production of Thromboxane, Prostaglandin and other products of Cyclooxygenase through inhibition of Prostaglandin synthetase.

Bicarfen 200 is indicated for the treatment of the following cases:
Pain relief, mild to moderate inflammation in headache, migraine, dysmenorrhea, dysmenorrhea, dental procedures, procedures genital tract,... Pain relief after major surgery for cancer treatment. Pain relief, anti-inflammatory common in juvenile rheumatoid arthritis, osteoarthritis. Reduce fever in children.

Allergy to any ingredient in Bicarfen 200. History of allergy to other drugs containing Ibuprofen. History of allergy to other non-steroidal anti-inflammatory drugs (NSAIDs). People with active peptic ulcer disease. People who have a history of or are suffering from asthma or other bronchospasm conditions. People with a history of or are suffering from a bleeding disorder. People with congestive heart failure, complications of decreased blood volume due to diuretics. People with gum disease (autoimmune disease). People with severe renal impairment. People who are being treated with Coumarin. Pregnant women in the last 3 months of pregnancy. Children < 7 years old.

Note: Take the drug after eating and the interval between 2 doses is at least 4 hours.

Pain relief:
Usual dose: Take 2-3 tablets (400 - 600mg)/time x 3 times/day. Maintenance dose: Take 1-2 tablets (200-400mg)/time x 3 times/day. Take no more than 16 tablets (3200mg)/day per day. Antipyretic:
Usual dose: Take 1-2 tablets (200-400mg)/time every 4-6 hours. Take no more than 6 tablets (1200mg) a day. Dysmenorrhea:
Usual dose: Take 1 tablet (200mg)/time every 4-6 hours. Increase dose: Take 2 tablets (400 mg) / time every 4-6 hours if symptoms increase or do not decrease. Take no more than 6 tablets (1200mg) a day.

Pain relief and fever reduction:
Children 7 - 10 years old: Take 1 tablet (200mg)/time or 30mg/kg/day x 3 times/day. Take no more than 12 tablets (2400mg) a day. Children 10-12 years old: Take 1.5 tablets (300mg)/time or 30mg/kg/day x 3 times/day. Take no more than 12 tablets (2400mg) a day. Children 12-18 years old: Initial dose: Take 1-2 tablets (200-400mg)/time x 3-4 times/day. Take no more than 12 tablets (2400mg) a day. Maintenance dose: Take 1-2 tablets (200-400mg)/time x 3 times/day. Pain relief and fever reduction:
Usual dose: Take 10mg/kg x 3-4 times/day. Increase dose: 60mg/kg/day in divided doses 3-4 times/day if symptoms increase or do not decrease. Take no more than 12 tablets (2400mg) a day.

Treatment with Bicarfen 200 with high doses or for a long time can cause side effects such as:
Common: Systemic symptoms such as fatigue, fever. Gastrointestinal symptoms such as nausea, vomiting, abdominal distension. Central nervous system symptoms such as headache, dizziness, vertigo, restlessness. Uncommon: Systemic symptoms such as allergies, bronchospasm in patients with asthma, rhinitis, urticaria. Gastrointestinal symptoms such as abdominal pain, gastrointestinal bleeding, progressive peptic ulcer. Central nervous system symptoms such as drowsiness, insomnia, tinnitus, visual disturbances, hearing loss. Bleeding time is prolonged. Rare: Systemic symptoms such as edema, skin rash, Stevens-Johnson syndrome, alopecia, hyponatremia. Central nervous system symptoms such as depression, blurred vision, color vision disorders, decreased visual acuity due to drug poisoning, aseptic and severe meningitis may cause coma. Hematological abnormalities such as anemia, leukopenia, neutropenia, eosinophilia, granulocytopenia, and thrombocytopenia. Gastrointestinal symptoms such as gallbladder contractility, abnormal liver function tests, hepatotoxicity, necrotizing enterocolitis, pancreatitis, Crohn's syndrome. Symptoms on the urinary system such as hematuria, acute renal failure, interstitial nephritis, nephrotic syndrome, cystitis. Should stop using the drug when detecting the above side effects after taking Bicarfen 200 and promptly notify the treating doctor or go to the nearest medical facility for timely treatment.

Care should be taken while using Bicarfen 200 in people with renal failure, heart failure, liver failure and diseases with disorders of plasma volume, because Ibuprofen can inhibit the synthesis of prostacyclin in the kidney, increasing the risk of stasis. water due to decreased blood flow to the kidneys. Bicarfen 200 should be used with caution in patients with elevated total bilirubin because of the risk that the active ingredient Ibuprofen competes with Bilirubin for binding to Albumin. Bicarfen 200 should be used with caution in patients with cardiovascular disease or risk factors for cardiovascular disease because ibuprofen increases blood pressure or worsens hypertension, increasing the risk of blood-related cardiovascular events. Masses such as myocardial infarction and stroke, severe can lead to death. Pregnant women: According to the US Food and Drug Administration (FDA), the active ingredient Ibuprofen in Bicarfen 200 is classified as safe in Group C, a group with evidence of risk in pregnant women. Therefore, Bicarfen 200 is contraindicated for use in pregnant women, especially in the last 3 months of pregnancy. Lactation: There is currently some research indicating that the active ingredient Ibuprofen in Bicarfen 200 can be excreted in breast milk, but at low concentrations it is unlikely to harm the infant at usual doses. However, it is currently recommended that the use of Bicarfen 200 in this population should be limited because of the potential risk of prostaglandin inhibition in the neonate. Drivers or machine operators should not use Bicarfen 200 because of possible side effects such as headache, dizziness, dizziness or visual disturbances.

The drug increases the risk of gastrointestinal complications when used with Bicarfen 200: Warfarin. Aspirin, Bicarfen 200 should be used 8 hours before or at least 30 minutes after aspirin. Corticosteroids. Other non-steroidal anti-inflammatory drugs (NSAIDs). The drug has increased blood levels when used with Bicarfen 200: Lithium. Digoxin . Bicarfen 200 reduces the urinary sodium excretion of furosemide and thiazide diuretics. Bicarfen 200 increases methotrexate toxicity. Magnesium hydroxide increases the absorption of Bicarfen 200. Bicarfen 200 reduces the antihypertensive effect of Angiotensin II receptor antagonists or ACE inhibitors. The above is general information and notes when using Bicarfen 200. In order to bring the best treatment results for themselves and their families, users should carefully read the instructions for use of Bicarfen 200, at the same time. Follow the instructions given by your doctor or pharmacist.